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Human Oral Bacterial Biofilms: Composition, Dynamics, and Pathogenesis

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Biofilm Infections

Abstract

The oral cavity has a diverse and dynamic bacterial flora that is significantly more complex than other sites in and on the human body, with the exception of the gut. Bacterial communities differ in composition depending on location in the mouth. Spatial relationships within the communities seem to be important for their function. Composition of the communities varies temporally and spatially: Changes in composition drive oral disease such as caries and periodontitis. Host response is key in the latter disease.

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Acknowledgements

Robert J. Palmer Jr. is supported by the Intramural Research Program, National Institute of Dental and Craniofacial Research, National Institutes of Health.

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Authors and Affiliations

  1. Oral Infection and Immunity Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, MD, USA

    Robert J. Palmer Jr

  2. Department of Periodontics, University of Washington, Seattle, WA, USA

    Richard Darveau

  3. Department of Oral Biology, University of Florida College of Dentistry, Gainesville, FL, USA

    Richard J. Lamont

  4. School of Dentistry, Faculty of Health Sciences, University of Aarhus, Aarhus, Denmark

    Bente Nyvad

  5. Department of Periodontology, The Forsyth Institute, Boston, MA, USA

    Ricardo P. Teles

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  1. Robert J. Palmer Jr
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  2. Richard Darveau
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  3. Richard J. Lamont
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  4. Bente Nyvad
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  5. Ricardo P. Teles
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Correspondence to Robert J. Palmer Jr .

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Editors and Affiliations

  1. Faculty of Health Sciences, Department of International Health, Immu, University of Copenhagen, Blegdamsvej 3B, Copenhagen Ø, DK-2200, Denmark

    Thomas Bjarnsholt

  2. Afsnit 9301, Department Clinical Microbiology, H:S Rigshospitalet, Juliane Maries Vej 22, Copenhagen Ø, DK-2100, Denmark

    Peter Østrup Jensen

  3. Afsnit 9301, Department for Clinical Microbiology, H:S Rigshospitalet, Juliane Maries Vej 22, Copenhagen Ø, DK-2100, Denmark

    Claus Moser

  4. Faculty of Health Sciences, Department of International Health, Immu, University of Copenhagen, Blegdamsveg 3B, Copenhagen Ø, DK-2100, Denmark

    Niels Høiby

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Palmer, R.J., Darveau, R., Lamont, R.J., Nyvad, B., Teles, R.P. (2011). Human Oral Bacterial Biofilms: Composition, Dynamics, and Pathogenesis. In: Bjarnsholt, T., Jensen, P., Moser, C., Høiby, N. (eds) Biofilm Infections. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6084-9_4

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