Adjuvant Endocrine Therapy
Adjuvant endocrine therapy is a mainstay of treatment for women with hormone-receptor (estrogen-receptor and/or progesterone-receptor) expressing breast cancers. Extensive clinical trials over decades have demonstrated compelling improvements in overall survival and disease-free survival with use of adjuvant endocrine therapy. Along with implementation of widespread screening mammography programs, use of adjuvant endocrine therapy has contributed substantially to the decline in breast cancer mortality seen in the US and other developed societies. Around the world, it is likely that adjuvant endocrine treatment has contributed more to the reduction in cancer mortality than any other therapy employed in medical oncology. This chapter provides an overview of current adjuvant endocrine approaches to breast cancer therapy.
KeywordsEstrogen Osteoporosis Assure Tamoxifen Androgen
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