Abstract
This chapter will discuss an approach to inflammatory skin disease. Recognition of inflammatory diseases of the skin is highly dependent on a group of histologic patterns: spongiotic, psoriasiform, interface, superficial perivascular, superficial and deep perivascular, interstitial, sclerosing, panniculitis, and alopecia. (Bullous disease is covered in Chapter 18.) The histologic patterns shape the differential diagnosis. The differential diagnosis is further refined by individual histologic features including specific epidermal (e.g., pattern of parakeratosis) or dermal (e.g., hemorrhage) findings and the nature of the inflammatory infiltrate. This chapter discusses common/important inflammatory dermatoses and their differential diagnosis. Immunodermatology is covered in Chapter 18.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
SUGGESTED READING
Almeyda J, Levantine A. Lichenoid drug eruptions. Br J Dermatol 1971;85:604–607.
Cooper PH, Innes DJ Jr, Greer KE. Acute febrile neutrophilic dermatosis (Sweet’s syndrome) and myeloproliferative disorders. Cancer 1983;51:1518–1526.
Cox AJ, Watson W. Histologic variations in lesions of psoriasis. Arch Dermatol 1972;106:503–506.
Crotty C, Pittelkow M, Muller SA. Eosinophilic spongiosis: A clinicopathological review of seventy-one cases. J Am Acad Dermatol 1983;8:337–343.
Doyle JA, Connolly SM, Hunziker, et al. Prurigo nodularis: A reappraisal of the clinical and histologic features. J Cutan Pathol 1979;6:392–403.
Farmer ER. The histopathology of graft-versus-host disease. Adv Dermatol 1986;1:173–188.
Farmer ER, Hood AF. Pathology of the Skin, 2nd ed. New York: McGraw-Hill, 2000.
Garcia de Silva L, Gardne PS. Pitryiasis rosea: A histologic and serologic study. Br J Dermatol 1968;80:514–515.
Hood AF, Mark EJ. Histopathologic diagnosis of pityriasis lichenoides et varioliformis acuta and its clinical correlation. Arch Dermatol 1982;118:478–482.
Huff JC, Weston WL, Tonnesen, MG. Erythema multiforme: A critical review of characteristics, diagnostic criteria, and causes. J Am Acad Dermatol 1983;8:763–775.
Hurwitz RM, DeTrana C. The cutaneous pathology of atopic dermatitis. Am J Dermpathol 1990;12:544–551.
Jerdan MS, Hood AF, Moore W, et al. Histopathologic comparisons of the subsets of lupus erythematosus. Arch Dermatol 1990;126:52.
Karp DL, Horn TD. Lymphomatoid papulosis. J Am Acad Dermatol 1994;30:379–395.
Kirsner RS, Pardes JB, Eaglstein WH, Falanga V. The clinical spectrum of lipodermatosclerosis. J Am Acad Dermatol 1993;28:623–627.
Krafchik BR. Localized cutaneous scleroderma. Semin Dermatol 1992;11:65–72.
Leinweber B, Colli C, Chott A, Kerl H, Cerroni L. Differential diagnosis of B lymphocytes with follicular growth pattern. Am J Dermatopathol 2004;26:4–13.
Longley J, Duffy TP, Kohn S. The mast cell and mast cell disease. J Am Acad Dermatol 1995;32:545–561; quiz 562–564.
Lowitt MH, Dover S. Necrobiosis lipoidica. J Am Acad Dermatol 1991;25:735–748.
Mali JWH, Kuiper JP, Hamers AA. Acro-angiodermatitis of the foot. Arch Dermatol 1965;92:515–518.
McKee PH, Calonje E, Granter SR. Pathology of the Skin with Clinical Correlation, 3rd ed. Philadelphia, PA: Elsevier Mosby, 2005.
Meffert JJ, Davis BM, Grimwood RE. Lichen sclerosus. J Am Acad Dermatol 1995;32:393–416; quiz 417–418.
Muhlbauer JE. Granuloma annulare. J Am Acad Dermatol 1980;3: 217–230.
Newton RC, Raimer SS. Pigmented pupuric eruption. Dermatol Clin 1985;3:165–169.
Paquet P, Pierard GE. Erythema multiforme and toxic epidermal necrolysis: a comparative study. Am J Dermatopathol 1997;19:127–132.
Ragaz A, Ackerman AB. Evolu tion, maturation, and regression of lesions of lichen planus: New observations and correlations of clinical and histologic findings. Am J Dermatopathol 1981;3:5–25.
Sanz Vico MD, De Diego V, Sanchez Yus E. Erythema nodosum versus nodular vasculitis. Int J Dermatol 1993;32:108–112.
Sellheyer K, Bergfeld WF. Histopathologic evaluation of alopecias. Am J Dermatopathol 2006;28:236–259. Review.
Solomon AR. The transversely sectioned scalp biopsy specimen: The technique and an algorithm for its use in the diagnosis of alopecia. Adv Dermatol 1994;9:127–157.
Soprano FF. Histologic criteria for the diagnosis of pityriasis rubra pilaris. Am J Dermatopathol 1986;8:277–283.
Weedon D. Skin Pathology, 2nd ed. New York: Churchill Livingstone; 2002.
Weedon D, ed. Skin Pathology, 3rd ed. New York: Churchill Livingstone; 2010.
Wells GC, Smith NP. Eosinophilic cellulites. Br J Dermatol 1979;100: 101–109.
Winkelmann RK. Panniculitis in connective tissue disease. Arch Dermatol 1983;119:336–344.
Immuodermatology is covered in Chapter 18
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2011 Springer Science+Business Media, LLC
About this chapter
Cite this chapter
Billings, S.D., Hood, A.F. (2011). Nonneoplastic Skin Diseases. In: Cheng, L., Bostwick, D. (eds) Essentials of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6043-6_19
Download citation
DOI: https://doi.org/10.1007/978-1-4419-6043-6_19
Published:
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4419-6042-9
Online ISBN: 978-1-4419-6043-6
eBook Packages: MedicineMedicine (R0)