Abstract
Medical practice based on information gleaned from molecular diagnostic testing is increasingly becoming the standard of care. Molecular information not only aids in diagnosis, but in prognostication and as a guide to targeted therapy. This chapter reviews current knowledge of relevant mutations in solid tumors in an organ-based approach. In addition, some technical aspects of molecular diagnostic testing are included, with emphasis on the advantages and disadvantages of different methods. Finally, the use of targeted therapies based on molecular findings is discussed where applicable.
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Moore, F.R., Press, R.D. (2011). Molecular Pathology of Solid Tumors. In: Cheng, L., Bostwick, D. (eds) Essentials of Anatomic Pathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-6043-6_12
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DOI: https://doi.org/10.1007/978-1-4419-6043-6_12
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