Atherectomy and Plaque Analysis
Atherosclerosis remains a dynamic disease in the vessel wall and understanding the genotypic and phenotypic biology has been significantly compromised by the inability to obtain tissue biopsies at relevant timepoints. Excision atherectomy allows for tissue to be removed during a therapeutic procedure for further analysis. Debulking of atherosclerotic lesions also facilitates expansion of the lumen without the bariatric pressure of balloons or the placement of a foreign body (i.e. metal stent). Sending debris downstream and creating distal occlusions in smaller vessels remains a critical issue in this technology.