Biomaterials in Cell Microencapsulation

  • Edorta Santos
  • Jon Zarate
  • Gorka Orive
  • Rosa Ma Hernández
  • José Luis Pedraz
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 670)

Abstract

The field of cell encapsulation is advancing rapidly. This cell-based technology permits the local and long-term delivery of a desired therapeutic product reducing or even avoiding the need of immunosuppressant drugs. The choice of a suitable material preserving the viability and functionality of enclosed cells becomes fundamental if a therapeutic aim is intended. Alginate, which is by far the most frequently used biomaterial in the field of cell microencapsulation, has been demonstrated to be probably the best polymer for this purpose due to its biocompatibility, easy manipulation, gel forming capacity and in vivo performance.

Keywords

Permeability Surfactant Mold Fourier Transform Infrared Spectroscopy Immobilization 

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Copyright information

© Landes Bioscience and Springer Science+Business Media 2010

Authors and Affiliations

  • Edorta Santos
    • 1
  • Jon Zarate
    • 1
  • Gorka Orive
    • 1
  • Rosa Ma Hernández
    • 1
  • José Luis Pedraz
    • 1
  1. 1.Laboratory of Pharmacy and Pharmaceutical TechnologyUniversity of the Basque CountryVitoria-GasteizSpain

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