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Localized Forms of Scleroderma

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Scleroderma

Abstract

Morphea, also called localized scleroderma, is a fibrosing disorder that resembles scleroderma (systemic sclerosis) microscopically, but typically has a quite different clinical presentation, course and possible pathophysiology. The individual with morphea has single or multiple circumscribed indurated cutaneous plaques that can have variable appearances, depending on the subtype (see classification below and Table 12.1). The main variants are circumscribed or plaque-type morphea (Fig. 12.1a), generalized morphea (Fig. 12.1b), linear morphea (Figs. 12.1c–f and 12.2a–d), and deep morphea or morphea profunda. Unlike scleroderma, systemic disease and involvement of internal organs are uncommon in morphea.

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Acknowledgment

We appreciate the expertise of Geralyn Bodeker, MS AHP in the Palo Alto Medical Foundation Group library and her help with obtaining reference material.

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Authors and Affiliations

  1. Department of Dermatology, Palo Alto Medical Foundation Group, Palo Alto, CA, 94301, USA

    Amy E. Gilliam MD

  2. Department of Dermatology and Dermatopathology, Palo Alto Medical Foundation Group, Palo Alto, CA, 94301, USA

    Anita C. Gilliam MD, PhD

Authors
  1. Amy E. Gilliam MD
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  2. Anita C. Gilliam MD, PhD
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Corresponding author

Correspondence to Amy E. Gilliam MD .

Editor information

Editors and Affiliations

  1. Feinberg School of Medicine, Northwestern University, E. Huron Street 240, Chicago, 60611-2909, Illinois, USA

    John Varga

  2. Royal Free and University College, Medical School, University College London, Rowland Street, London, NW3 2PF, United Kingdom

    Christopher P. Denton

  3. School of Medicine, Div. Rheumatology, Johns Hopkins University, Eastern Avenue 5200, Baltimore, 21224, Maryland, USA

    Fredrick M. Wigley

Additional information

This chapter is dedicated to James N. Gilliam, MD, a loving husband and father, who inspired our careers and our mutual interests in autoimmunity.

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© 2012 Springer Science+Business Media, LLC

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Gilliam, A.E., Gilliam, A.C. (2012). Localized Forms of Scleroderma. In: Varga, J., Denton, C., Wigley, F. (eds) Scleroderma. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-5774-0_12

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  • DOI: https://doi.org/10.1007/978-1-4419-5774-0_12

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