Abstract
The Kölliker-Fuse nucleus (KF) is an integral part of the central pattern generator for breathing and shows postnatal development of synaptic functions and cyto-architectural structure. Here, we analyzed the postnatal changes in cell morphology of biocytin-labelled KF neurones. Developmental analyses revealed an increasing size of somas and dendritic length. These changes were accompanied by changes in the orientation of the main dendritic branches from a diffuse orientation in neonates to a predominant medio-lateral orientation in juveniles. These developmental changes may allow for synaptic contacts with multiple ascending fibre tracts required for the processing of multi-modal respiratory inputs in the KF.
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Acknowledgements
The study was supported by a grant from the BMBF (BCCN, 01GQ0432).
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Reuter, J., Kron, M., Dutschmann, M. (2010). Postnatal Changes in Morphology and Dendritic Organization of Neurones Located in the Area of the Kölliker-Fuse Nucleus of Rat. In: Homma, I., Onimaru, H., Fukuchi, Y. (eds) New Frontiers in Respiratory Control. Advances in Experimental Medicine and Biology, vol 669. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5692-7_8
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DOI: https://doi.org/10.1007/978-1-4419-5692-7_8
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