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Ontogeny of Cl- Homeostasis in Mouse Hypoglossal Nucleus

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New Frontiers in Respiratory Control

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 669))

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Abstract

We tested the immunoreactivity of KCC2 using KCC2 antibody in the developmental mouse medulla. Age-dependent changes in immunoreactivity were remarkable in the hypoglossal nucleus, and interestingly, the immunoreactivity in the hypoglossal nucleus relative to the dorsal vagal nucleus at P0 appeared to be higher than that of P7. Thus Cl− homeostasis in the hypoglossal nucleus might be differentially regulated in the developmental stage.

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Acknowledgments

This research was partially supported by the Ministry of Education, Science, Sports and Culture, Grant-in-Aid for Young Scientists (B), 21791046, 2009.

Author information

Authors and Affiliations

  1. Division of Physiome, Department of Physiology, Hyogo College of Medicine, Nishinomiya, Hyogo, Japan

    Akihito Okabe, Akiko Arata & Yoshitaka Oku

  2. Department of Anatomy 2, Ryukyu University Faculty of Medicine, Ryukyu, Japan

    Chitoshi Takayama

  3. Department of Physiology, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan

    Atsuo Fukuda

Authors
  1. Akihito Okabe
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  2. Akiko Arata
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  3. Yoshitaka Oku
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  4. Chitoshi Takayama
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  5. Atsuo Fukuda
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Corresponding author

Correspondence to Akihito Okabe .

Editor information

Editors and Affiliations

  1. Showa University School of Medicine, Hatanodai, Shinagawa-ku 1-5-8-5-8, Tokyo, 142-8555, Japan

    Ikuo Homma

  2. Showa University School of Medicine, Hatanodai, Shinagawa-ku 1-5-8-5-8, Tokyo, 142-8555, Japan

    Hiroshi Onimaru

  3. Jyuntendo University School of Medicine, Hongo, Bunkyo-ku 2-1-1-1-1, Tokyo, 113-8421, Japan

    Yoshinosuke Fukuchi

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Okabe, A., Arata, A., Oku, Y., Takayama, C., Fukuda, A. (2010). Ontogeny of Cl- Homeostasis in Mouse Hypoglossal Nucleus. In: Homma, I., Onimaru, H., Fukuchi, Y. (eds) New Frontiers in Respiratory Control. Advances in Experimental Medicine and Biology, vol 669. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5692-7_6

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