How Does Stress Work? The Role of Memes in Epigenesis
Stress responsiveness is affected by early experience. For example, in rats, high grooming and licking by mother in early life results in decreased reactivity to later stress by increasing the expression of glucocorticoid receptor genes in the brain. Memories of early experience and resulting changes in genes (epigenesis) determine stress sensitivity in later life. Epigenesis may result in increased or decreased susceptibility to influx of stress memes.
KeywordsGlucocorticoid Receptor Chronic Stress Maternal Behavior Adult Offspring Locus Ceruleus
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