Abstract
Oscillatory activity in the higher (gamma) frequency range in electro- or magnetoencephalogram (EEG or MEG, respectively) has been proposed as a correlate of cortical network synchronization. This chapter reviews the evidence for an involvement of gamma-band activity in multisensory integration. The relevant studies are grouped by the level at which oscillatory EEG or MEG data were analyzed. The first section describes reports of topographically unspecific or widespread spectral activity. The second part focuses on studies demonstrating topographically local activity both at the electrode/sensor level and at the cortical source level. Finally, reports of cortico-cortical interactions as suggested by EEG/MEG coherence or phase synchrony are summarized. Gamma-band activity increases have been reported for temporally, spatially, or semantically matching bimodal stimulation. Some studies, however, have reported enhanced oscillatory signals also to incongruent stimuli, suggesting an important role of task requirements and attentional factors.
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Amedi A, von Kriegstein K, van Atteveldt NM, Beauchamp MS, Naumer MJ (2005) Functional imaging of human crossmodal identification and object recognition. Exp Brain Res 166:559–571
Bauer M, Oostenveld R, Fries P (2009) Tactile stimulation accelerates behavioral responses to visual stimuli through enhancement of occipital gamma-band activity. Vision Res 49:931–942
Bauer M, Oostenveld R, Peeters M, Fries P (2006) Tactile spatial attention enhances gamma-band activity in somatosensory cortex and reduces low-frequency activity in parieto-occipital areas. J Neurosci 26:490–501
Beauchamp MS (2005) See me, hear me, touch me: multisensory integration in lateral occipital-temporal cortex. Curr Opin Neurobiol 15:145–153
Beauchamp MS, Lee KE, Argall BD, Martin A (2004) Integration of auditory and visual information about objects in superior temporal sulcus. Neuron 41:809–823
Bhattacharya J, Shams L, Shimojo S (2002) Sound-induced illusory flash perception: role of gamma band responses. Neuroreport 13:1727–1730
Busch NA, Herrmann CS, Müller MM, Lenz D, Gruber T (2006) A cross-laboratory study of event-related gamma activity in a standard object recognition paradigm. Neuroimage 33:1169–1177
Doehrmann O, Naumer MJ (2008) Semantics and the multisensory brain: how meaning modulates processes of audio-visual integration. Brain Res 1242:136–150
Doehrmann O, Naumer MJ, Volz S, Kaiser J, Altmann CF (2008) Probing category selectivity for environmental sounds in the human auditory brain. Neuropsychologia 46:2776–2786
Doesburg SM, Emberson LL, Rahi A, Cameron D, Ward LM (2008) Asynchrony from synchrony: long-range gamma-band neural synchrony accompanies perception of audiovisual speech asynchrony. Exp Brain Res 185:11–20
Driver J, Noesselt T (2008) Multisensory interplay reveals crossmodal influences on ‘sensory-specific’ brain regions, neural responses, and judgments. Neuron 57:11–23
Eckhorn R, Bauer R, Jordan W, Brosch M, Kruse W, Munk M, Reitboeck HJ (1988) Coherent oscillations: a mechanism of feature linking in the visual cortex? Multiple electrode and correlation analyses in the cat. Biol Cybern 60:121–130
Engel AK, Singer W (2001) Temporal binding and the neural correlates of sensory awareness. Trends Cogn Sci 5:16–25
Foxe JJ, Wylie GR, Martinez A, Schroeder CE, Javitt DC, Guilfoyle D, Ritter W, Murray MM (2002) Auditory-somatosensory multisensory processing in auditory association cortex: an fMRI study. J Neurophysiol 88:540–543
Fries P (2005) A mechanism for cognitive dynamics: neuronal communication through neuronal coherence. Trends Cogn Sci 9:474–480
Fries P, Nikolic D, Singer W (2007) The gamma cycle. Trends Neurosci 30:309–316
Fries P, Roelfsema PR, Engel AK, König P, Singer W (1997) Synchronization of oscillatory responses in visual cortex correlates with perception in interocular rivalry. Proc Natl Acad Sci U S A 94:12699–12704
Ghazanfar AA, Schroeder CE (2006) Is neocortex essentially multisensory? Trends Cogn Sci 10:278–285
Ghazanfar AA, Chandrasekaran C, Logothetis NK (2008) Interactions between the superior temporal sulcus and auditory cortex mediate dynamic face/voice integration in rhesus monkeys. J Neurosci 28:4457–4469
Gray CM, König P, Engel AK, Singer W (1989) Oscillatory responses in cat visual cortex exhibit inter-columnar synchronization which reflects global stimulus properties. Nature 338:334–337
Gruber T, Müller MM, Keil A, Elbert T (1999) Selective visual-spatial attention alters induced gamma band responses in the human EEG. Clin Neurophysiol 110:2074–2085
Gruber T, Tsivilis D, Montaldi D, Müller MM (2004) Induced gamma band responses: an early marker of memory encoding and retrieval. Neuroreport 15:1837–1841
Hein G, Doehrmann O, Muller NG, Kaiser J, Muckli L, Naumer MJ (2007) Object familiarity and semantic congruency modulate responses in cortical audiovisual integration areas. J Neurosci 27:7881–7887
Herrmann CS, Munk MH, Engel AK (2004) Cognitive functions of gamma-band activity: memory match and utilization. Trends Cogn Sci 8:347–355
Hummel F, Gerloff C (2005) Larger interregional synchrony is associated with greater behavioral success in a complex sensory integration task in humans. Cereb Cortex 15:670–678
Jensen O, Kaiser J, Lachaux JP (2007) Human gamma-frequency oscillations associated with attention and memory. Trends Neurosci 30:317–324
Jokisch D, Jensen O (2007) Modulation of gamma and alpha activity during a working memory task engaging the dorsal or ventral stream. J Neurosci 27:3244–3251
Kaiser J, Lutzenberger W, Ackermann H, Birbaumer N (2002) Dynamics of gamma-band activity induced by auditory pattern changes in humans. Cereb Cortex 12:212–221
Kaiser J, Ripper B, Birbaumer N, Lutzenberger W (2003) Dynamics of gamma-band activity in human magnetoencephalogram during auditory pattern working memory. Neuroimage 20:816–827
Kaiser J, Hertrich I, Ackermann H, Lutzenberger W (2006) Gamma-band activity over early sensory areas predicts detection of changes in audiovisual speech stimuli. Neuroimage 30:1376–1382
Kaiser J, Lutzenberger W, Preissl H, Ackermann H, Birbaumer N (2000) Right-hemisphere dominance for the processing of sound-source lateralization. J Neurosci 20:6631–6639
Kaiser J, Hertrich I, Ackermann H, Mathiak K, Lutzenberger W (2005) Hearing lips: gamma-band activity during audiovisual speech perception. Cereb Cortex 15:646–653
Kaiser J, Heidegger T, Wibral M, Altmann CF, Lutzenberger W (2008) Distinct gamma-band components reflect the short-term memory maintenance of different sound lateralization angles. Cereb Cortex 18:2286–2295
Kanayama N, Ohira H (2009) Multisensory processing and neural oscillatory responses: separation of visuotactile congruency effect and corresponding electroencephalogram activities. Neuroreport 20:289–293
Kanayama N, Sato A, Ohira H (2007) Crossmodal effect with rubber hand illusion and gamma-band activity. Psychophysiology 44:392–402
Kayser C, Petkov CI, Logothetis NK (2008) Visual modulation of neurons in auditory cortex. Cereb Cortex 18:1560–1574
Kayser C, Petkov CI, Augath M, Logothetis NK (2005) Integration of touch and sound in auditory cortex. Neuron 48:373–384
Lakatos P, Chen CM, O'Connell MN, Mills A, Schroeder CE (2007) Neuronal oscillations and multisensory interaction in primary auditory cortex. Neuron 53:279–292
Lewis JW, Wightman FL, Brefczynski JA, Phinney RE, Binder JR, DeYoe EA (2004) Human brain regions involved in recognizing environmental sounds. Cereb Cortex 14:1008–1021
Lutzenberger W, Pulvermüller F, Elbert T, Birbaumer N (1995) Visual stimulation alters local 40-Hz responses in humans: an EEG-study. Neurosci Lett 183:39–42
Lutzenberger W, Ripper B, Busse L, Birbaumer N, Kaiser J (2002) Dynamics of gamma-band activity during an audiospatial working memory task in humans. J Neurosci 22:5630–5638
Maier JX, Chandrasekaran C, Ghazanfar AA (2008) Integration of bimodal looming signals through neuronal coherence in the temporal lobe. Curr Biol 18:963–968
McGurk H, MacDonald J (1976) Hearing lips and seeing voices. Nature 264:746–748
Merabet LB, Swisher JD, McMains SA, Halko MA, Amedi A, Pascual-Leone A, Somers DC (2007) Combined activation and deactivation of visual cortex during tactile sensory processing. J Neurophysiol 97:1633–1641
Meredith MA (2002) On the neuronal basis for multisensory convergence: a brief overview. Cogn Brain Res 14:31–40
Meredith MA, Stein BE (1983) Interactions among converging sensory inputs in the superior colliculus. Science 221:389–391
Mesulam MM (1998) From sensation to cognition. Brain 121:1013–1052
Mishra J, Martinez A, Sejnowski TJ, Hillyard SA (2007) Early cross-modal interactions in auditory and visual cortex underlie a sound-induced visual illusion. J Neurosci 27:4120–4131
Molholm S, Ritter W, Murray MM, Javitt DC, Schroeder CE, Foxe JJ (2002) Multisensory auditory-visual interactions during early sensory processing in humans: a high-density electrical mapping study. Cogn Brain Res 14:115–128
Müller MM, Keil A (2004) Neuronal synchronization and selective color processing in the human brain. J Cogn Neurosci 16:503–522
Noppeney U, Josephs O, Hocking J, Price CJ, Friston KJ (2008) The effect of prior visual information on recognition of speech and sounds. Cereb Cortex 18:598–609
Osipova D, Takashima A, Oostenveld R, Fernandez G, Maris E, Jensen O (2006) Theta and gamma oscillations predict encoding and retrieval of declarative memory. J Neurosci 26:7523–7531
Sakowitz OW, Quiroga RQ, Schurmann M, Basar E (2001) Bisensory stimulation increases gamma-responses over multiple cortical regions. Cogn Brain Res 11:267–279
Sakowitz OW, Quian Quiroga R, Schurmann M, Basar E (2005) Spatio-temporal frequency characteristics of intersensory components in audiovisually evoked potentials. Cogn Brain Res 23:316–326
Schneider TR, Debener S, Oostenveld R, Engel AK (2008) Enhanced EEG gamma-band activity reflects multisensory semantic matching in visual-to-auditory object priming. Neuroimage 42:1244–1254
Schroeder CE, Smiley J, Fu KG, McGinnis T, O'Connell MN, Hackett TA (2003) Anatomical mechanisms and functional implications of multisensory convergence in early cortical processing. Int J Psychophysiol 50:5–17
Senkowski D, Talsma D, Herrmann CS, Woldorff MG (2005) Multisensory processing and oscillatory gamma responses: effects of spatial selective attention. Exp Brain Res 166:411–426
Senkowski D, Molholm S, Gomez-Ramirez M, Foxe JJ (2006) Oscillatory beta activity predicts response speed during a multisensory audiovisual reaction time task: a high-density electrical mapping study. Cereb Cortex 16:1556–1565
Senkowski D, Schneider TR, Foxe JJ, Engel AK (2008) Crossmodal binding through neural coherence: implications for multisensory processing. Trends Neurosci 31:401–409
Senkowski D, Schneider TR, Tandler F, Engel AK (2009) Gamma-band activity reflects multisensory matching in working memory. Exp Brain Res 198:363–372
Senkowski D, Talsma D, Grigutsch M, Herrmann CS, Woldorff MG (2007) Good times for multisensory integration: effects of the precision of temporal synchrony as revealed by gamma-band oscillations. Neuropsychologia 45:561–571
Shams L, Kamitani Y, Shimojo S (2000) What you see is what you hear. Nature 408:788
Singer W, Engel AK, Kreiter A, Munk MHJ, Neuenschwander S, Roelfsema PR (1997) Neuronal assemblies: necessity, signature and detectability. Trends Cogn Sci 1:252–261
Stein BE, Meredith MA (1993) The merging of the senses. MIT Press, Cambridge, MA
Tallon-Baudry C, Bertrand O, Delpuech C, Pernier J (1996) Stimulus specificity of phase-locked and non-phase-locked 40 Hz visual responses in human. J Neurosci 16:4240–4249
Tallon-Baudry C, Bertrand O, Peronnet F, Pernier J (1998) Induced gamma-band activity during the delay of a visual short-term memory task in humans. J Neurosci 18:4244–4254
Wallace MT, Meredith MA, Stein BE (1998) Multisensory integration in the superior colliculus of the alert cat. J Neurophysiol 80:1006–1010
Widmann A, Gruber T, Kujala T, Tervaniemi M, Schroger E (2007) Binding symbols and sounds: evidence from event-related oscillatory gamma-band activity. Cereb Cortex 17:2696–2702
Womelsdorf T, Schoffelen JM, Oostenveld R, Singer W, Desimone R, Engel AK, Fries P (2007) Modulation of neuronal interactions through neuronal synchronization. Science 316:1609–1612
Wyart V, Tallon-Baudry C (2008) Neural dissociation between visual awareness and spatial attention. J Neurosci 28:2667–2679
Yuval-Greenberg S, Deouell LY (2007) What you see is not (always) what you hear: induced gamma band responses reflect cross-modal interactions in familiar object recognition. J Neurosci 27:1090–1096
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Kaiser, J., Naumer, M.J. (2010). Cortical Oscillations and Multisensory Interactions in Humans. In: Kaiser, J., Naumer, M. (eds) Multisensory Object Perception in the Primate Brain. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5615-6_5
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DOI: https://doi.org/10.1007/978-1-4419-5615-6_5
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