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Timing of Renal Replacement Therapy

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Book cover Intensive Care Medicine

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Abstract

Acute kidney injury (AKI) defined by the sensitive Risk, Injury, Failure, Loss, and End-stage kidney disease (RIFLE) or AKI criteria occurs in 10 to 60 % of intensive care unit (ICU) patients, and is associated with increased mortality [1, 2]. Despite advances in ICU care, the mortality of patients with AKI has remained more or less stable over recent years [3]. A possible explanation for this unchanged mortality in AKI includes the plethora of definitions used to define AKI, but also differences in case mix, including more older and more seriously ill patients.

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References

  1. Hoste EA, Clermont G, Kersten A, et al (2006) RIFLE criteria for acute kidney injury are associated with hospital mortality in critically ill patients: A cohort analysis. Crit Care 10: R73

    Article  PubMed  Google Scholar 

  2. Hoste EA, De Corte W (2007) Epidemiology of AKI in the ICU. Acta Clin Belg 2: 314–317

    Google Scholar 

  3. Ympa YP, Sakr Y, Reinhart K, Vincent JL (2005) Has mortality from acute renal failure decreased? A systematic review of the literature. Am J Med 118: 827–832

    Article  PubMed  Google Scholar 

  4. Mehta LR (2001) Indications for dialysis in the ICU: Renal replacement versus renal support. Blood Purif 19: 227–232

    Article  CAS  PubMed  Google Scholar 

  5. Palevsky PM (2007) Clinical review: Timing and dose of continuous renal replacement therapy in acute kidney injury. Crit Care 11: 232

    Article  PubMed  Google Scholar 

  6. Kolff WJ (1947) New Ways of Treating Uremia: Artificial Kidney, Peritioneal Lavage, Intestinal Lavage. J&A Churchill Ltd, London.

    Google Scholar 

  7. Teschan P, Baxter C, O'Brian T, et al (1960) Prophylactic hemodialysis in the treatment of acute renal failure. Ann Intern Med 53: 992–1016

    CAS  PubMed  Google Scholar 

  8. Conger JD (1975) A controlled evaluation of prophylactic dialysis in post-traumatic acute renal failure. J Trauma 15: 1056–1063

    Article  CAS  PubMed  Google Scholar 

  9. Gillum DM, Dixon BS, Yanover MJ, et al (1986) The role of intensive dialysis in acute renal failure. Clin Nephrol 25: 249–255

    CAS  PubMed  Google Scholar 

  10. Bouman CS, Oudemans-Van Straaten HM, Tijssen JG, Zandstra DF, Kesecioglu J (2002) Effects of early high-volume continuous venovenous hemofiltration on survival and recovery of renal function in intensive care patients with acute renal failure: a prospective, randomized trial. Crit Care Med 30: 2205–2211

    Article  PubMed  Google Scholar 

  11. Gibney N, Hoste E, Burdmann EA, et al (2008) Timing of initiation and discontinuation of renal replacement therapy in AKI: Unanswered key questions. Clin J Am Soc Nephrol 3: 876–880

    Article  PubMed  Google Scholar 

  12. Liu KD, Himmelfarb J, Paganini E, et al (2006) Timing of initiation of dialysis in critically ill patients with acute kidney injury. Clin J Am Soc Nephrol 1: 915–919

    Article  CAS  PubMed  Google Scholar 

  13. Kleinknecht D, Jungers P, Chanard J, Barbanel C, Ganeval D (1972) Uremic and non-uremic complications in acute renal failure: Evaluation of early and frequent dialysis on prognosis. Kidney Int 1: 190–196

    Article  CAS  PubMed  Google Scholar 

  14. Uchino S, Kellum JA, Bellomo R, et al (2005) Acute renal failure in critically ill patients: a multinational, multicenter study. JAMA 294: 813–818

    Article  CAS  PubMed  Google Scholar 

  15. Bagshaw SM, Uchino S, Bellomo R, et al (2009) Timing of renal replacement therapy and clinical outcomes in critically ill patients with severe acute kidney injury. J Crit Care 24: 129–140

    Article  PubMed  Google Scholar 

  16. De Corte W, De Waele J, Blot S, et al (2008) Serum urea as a marker for initiation of renal replacement therapy in ICU patients with acute kidney injury. Crit Care 12: P478

    Article  Google Scholar 

  17. Waikar SS, Bonventre JV, (2006) Can we rely on blood urea nitrogen as a biomarker to determine when to initiate dialysis? Clin J Am Soc Nephrol 1: 903–904

    Article  PubMed  Google Scholar 

  18. Payen D, de Pont A, Sakr Y, et al (2008) A positive tluid balance is associated with a worse outcome in patients with acute renal failure. Crit Care 12: R74

    Article  PubMed  Google Scholar 

  19. Bouchard J, Soroko S, Chertow G, et al (2009) Fluid accumulation, survival and recovery of kidney function in critically ill patients with acute kidney injury. Kidney Int 76: 422–427

    Article  PubMed  Google Scholar 

  20. Silvester W, Bellomo R, Cole L (2001) Epidemiology, management and outcome of severe acute renal failure of critical illness in Australia. Crit Care Med 29: 1910–1915

    Article  CAS  PubMed  Google Scholar 

  21. Metnitz PG, Krenn CG, Steltzer H, et al (2002) Effect of acute renal failure requiring renal replacement therapy on outcome in critically ill patients. Crit Care Med 30: 2051–2058

    Article  PubMed  Google Scholar 

  22. Mehta RL, McDonald B, Gabbai F, et al (2002) Nephrology consultation in acute renal failure: does timing matter? Am J Med 113: 456–461

    Article  PubMed  Google Scholar 

  23. Seabra V, Balk E, Liangos O, Sosa M, Cendoroglo M, Jaber B (2008) Timing of renal replacement therapy initiation in acute renal failure: A meta-analysis. Am J Kidney Dis 52: 272–284

    Article  PubMed  Google Scholar 

  24. Pearse R, Dawson G, Fawcett J, Rhodes A, Grounds RM, Bennett ED (2005) Early goaldirected therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial. Crit Care 9: R687–693

    Article  PubMed  Google Scholar 

  25. Rivers E, Nguyen B, Havstad S, et al (2001) Early goal-directed therapy in the treatment of severe sepsis and septic shock N Engl J Med 345: 1368–1377

    Article  CAS  PubMed  Google Scholar 

  26. Andrade L, Cleto S, Seguro AC (2007) Door-to-dialysis time and daily hemodialysis in patients with leptospirosis: Impact on mortality. Clin J Am Soc Nephrol 2: 739–744

    Article  PubMed  Google Scholar 

  27. Schiftl H, Fischer R (2008) Five-year outcomes of severe acute kidney injury requiring renal replacement therapy. Nephrol Dial Transplant 23: 2235–2241

    Article  Google Scholar 

  28. Ishani JL, Xue J, Himmelfarb PW, Eggers PL (2009) Acute kidney injury increases risk of ESRD among elderly. J Am Soc Nephro 120: 8–10

    Google Scholar 

  29. Parsons FM, Hobson SM, Blagg CR, et al (1961) Optimum time for dialysis in acute reversible renal failure. Description and value of an improved dialyser with large surface area. Lancet 1: 129–134

    Article  CAS  PubMed  Google Scholar 

  30. Fischer RP, Griffen WO, Reiser M, et al (1966) Early dialysis in the treatment of acute renal failure. Surg Gynecol Obstet 123: 1019–1023

    CAS  PubMed  Google Scholar 

  31. Gettings LG, Reynolds HN, Scalea T (1999) Outcome in post-traumatic acute renal failure when continuous renal replacement therapy is applied early vs. late. Intensive Care Med 25: 805–813

    Article  CAS  PubMed  Google Scholar 

  32. Foland JA, Fortenberry JD, Warshaw BL, et al (2004) Fluid overload before continuous hemofiltration and survival in critically ill children: A retrospective analysis. Crit Care Med 32: 1771–1776

    Article  PubMed  Google Scholar 

  33. Goldstein SL, Currier H, Graf C, Cosio CC, Brewer ED, Sachdeva R (2001) Outcome in children receiving continuous venovenous hemofiltration. Pediatrics 107: 1309–1312

    Article  CAS  PubMed  Google Scholar 

  34. Bent P, Tan HK, Bellomo R, et al (2001) Early and intensive continuous hemofiltration for severe renal failure after cardiac surgery. Ann Thorac Surg 71: 832–837

    Article  CAS  PubMed  Google Scholar 

  35. Demirkilic U, Kuralay E, Yenicesu M, et al (2004) Timing of replacement therapy for acute renal failure after cardiac surgery. J Cardiac Surg 19: 17–20

    Article  Google Scholar 

  36. Elahi MM, Lim MY, Joseph RN, Dhannapuneni RR, Spyt TJ (2004) Early hemofiltration improves survival in post-cardiotomy patients with acute renal failure. Eur J Cardiothorac Surg 26: 1027–1031

    Article  PubMed  Google Scholar 

  37. Dellinger RP, Carlet JM, Masur H, et al (2004) Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Crit Care Med 32: 858–873

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Anesthesia and Intensive Care, AZ Groeninge, Houtmarkt, 8500, Kortrijk, Belgium

    W. De Corte

  2. Intensive Care Unit ZiekenhuisNetwerk Antwerpen, ZNA Stuivenberg, Lange Beeldekensstraat 267, 2060, Antwerp, Belgium

    I. De Laet

  3. Department of Intensive Care, University Hospital, De Pintelaan 185, 9000, Ghent, Belgium

    E. A. J. Haste

Authors
  1. W. De Corte
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  2. I. De Laet
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  3. E. A. J. Haste
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Editor information

Editors and Affiliations

  1. Department of Intensive Care Erasme Hospital, Université libre de Bruxelles, Route de Lennik 808, 1070, Brussels, Belgium

    Jean-Louis Vincent MD, PhD, FCCM, FCCP (Head) (Head)

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De Corte, W., De Laet, I., Haste, E.A.J. (2010). Timing of Renal Replacement Therapy. In: Vincent, JL. (eds) Intensive Care Medicine. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-5562-3_35

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  • DOI: https://doi.org/10.1007/978-1-4419-5562-3_35

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-5561-6

  • Online ISBN: 978-1-4419-5562-3

  • eBook Packages: MedicineMedicine (R0)

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