Fertility Preservation in Gynecologic Malignancies

  • Christine E. Richter
  • Peter E. Schwartz


Twenty-one percent of gynecologic cancers affect women in the reproductive-age group. Since an increasing number of women are delaying childbearing and overall survival of many gynecologic malignancies has improved, fertility preservation is an important issue for these young patients. The standard treatment of gynecologic cancers often includes the removal of the ovaries and/or the uterus. Conservative surgery consists of the preservation of at least the uterine corpus and part of one ovary in order to maintain the reproductive potential. While fertility-preserving options are promising, the majority of these procedures are not considered standard of care. The selection of appropriate patients and counseling of interested patients are challenging. Close collaborations between the gynecologic oncologists, reproductive endocrinologists, geneticists, and maternal-fetal medicine specialists are necessary. This chapter presents the current standard of care for each type of gynecologic malignancy and discusses the options of fertility preservation for each type of cancer, focusing on the indications, techniques, and reproductive and oncological outcomes of fertility-preserving surgery.


Fertility preservation in gynecologic malignancy Gynecologic malignancy and fertility Ovarian cancer and fertility Uterine cancer and fertility Conservative surgery in gynecologic malignancy Ovarian preservation Trachelectomy Tumorectomy 


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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Christine E. Richter
    • 1
  • Peter E. Schwartz
    • 2
  1. 1.Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive SciencesYale University School of MedicineNew HavenUSA
  2. 2.Department of Obstetrics, Gynecology and Reproductive SciencesYale University School of MedicineNew HavenUSA

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