Autoimmune Thyroid Diseases

  • Ashraf Khan
  • Otto Walter
Chapter
Part of the Molecular Pathology Library book series (MPLB, volume 3)

Abstract

The discovery in 1956 that Hashimoto’s thyroiditis is an autoimmune disease spelled the end of the concept of horror autotoxicus and introduced the reality of human autoimmunity. Soon after, Graves’ disease was discovered to be directly caused by a serum factor, subsequently identified as an autoantibody. These diseases have served as invaluable models for the understanding of the organ specific autoimmunity. While Graves’ disease and Hashimoto’s thyroiditis are the two most common autoimmune thyroid diseases, autoimmune etiology has been also implicated in other forms of thyroiditides like Riedel’s, postpartum, silent and focal lymphocytic thyroiditis.

Keywords

Fatigue Hepatitis Europe Lymphoma Iodine 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Ashraf Khan
    • 1
  • Otto Walter
    • 1
  1. 1.Department of PathologyUMass Memorial Medical Center, University of Massachusetts Medical SchoolWorcesterUSA

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