Introduction

Abstract

At first glance one may wonder why an entire book is devoted to Müller cells, a cell type that clearly represents a minority in our central nervous system (CNS): Out of an estimated total number of about 200 billions of cells in our CNS, the 8–10 millions of Müller cells in our two eyes constitute not more than some 0.005%. To make things even worse – Müller cells do not belong to the highly esteemed neurons but to the glia, a family of cells which for more than a century had been thought of as a sort of mere filling material between the neurons… So one may wonder even more why our research group – together with an increasing number of scientists worldwide – focuses their research on these cells now for a quarter of a century, with no end in sight.