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Surgical Management of Colon Cancer

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The ASCRS Textbook of Colon and Rectal Surgery

Abstract

All colorectal cancer develops from a single transformed cell which ultimately grows large enough to present as a macroscopic lesion involving the lumen of the bowel. The staging of colorectal cancer is most dependent upon the depth of penetration of the bowel wall and the involvement of regional lymph nodes. An increasingly wide variety of putative molecular markers for aggressiveness and metastatic potential have been analyzed; however, the two most important prognostic indicators remain the degree of bowel wall invasion and status of the lymph nodes. This fact has lead to the continued importance of adequate locoregional oncological principles when performing curative resections of colon cancer. The purpose of this chapter is to primarily address issues directly related to the safe and oncologically sound methods of performing a curative resection of a colonic carcinoma. Important and related issues, such as clinicopathologic staging systems, the role of adjuvant or neoadjuvant treatments, and molecular markers are addressed in detail in other sections of this text.

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Acknowledgment.

This chapter was written by Robert Fry and Anthony Senagore in the previous version of this textbook.

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Authors and Affiliations

  1. Department of Surgery, Section of Colon and Rectal Surgery, Barnes Jewish Hospital/Washington University School of Medicine, St. Louis, MO, USA

    Matthew Mutch MD

  2. Division of Colorectal Surgery, University of Rochester, Strong Memorial Hospital, Rochester, NY, USA

    Christina Cellini MD

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  1. Matthew Mutch MD
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  2. Christina Cellini MD
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Editors and Affiliations

  1. Department of Colon and Rectal Surgery, Louisiana State University Health Sciences Center, New Orleans, Louisiana, USA

    David E. Beck MD, FACS, FASCRS

  2. Department of Colorectal Surgery, Lahey Clinic, Tufts University School of Medicine, Burlington, Massachusetts, USA

    Patricia L. Roberts MD, FACS, FASCRS

  3. Section of Colon and Rectal Surgery, Rush Medical Center, Chicago, Illinois, USA

    Theodore J. Saclarides MD, FACS, FASCRS

  4. Department of Surgery, Spectrum Health, Grand Rapids, Michigan, USA

    Anthony J. Senagore MD, FACS, FASCRS

  5. Department of Surgery, UCI Medical Center, Orange, California, USA

    Michael J. Stamos MD, FACS, FASCRS

  6. Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida, USA

    Steven D. Wexner MD, FACS, FASCRS, FRCS, FRCS(Ed)

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© 2011 ASCRS (American Society of Colon and Rectal Surgeons)

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Mutch, M., Cellini, C. (2011). Surgical Management of Colon Cancer. In: Beck, D.E., Roberts, P.L., Saclarides, T.J., Senagore, A.J., Stamos, M.J., Wexner, S.D. (eds) The ASCRS Textbook of Colon and Rectal Surgery. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1584-9_41

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