Abstract
Within the field of clinical epidemiology bias is always a concern and the field is plagued by studies which have not taken this into account. Lack of insights in problems caused by confounding by indication, differential misclassification of exposure, differential misclassification of outcome, and selection bias have resulted in premature claims of causality. However, it is fair to say that during the last decade there has been a growing awareness of the problems, but it is still too easy to find many examples of a suboptimal study design where bias has led to wrong results.
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References
Lagergren J, Ye W, Ekbom A. Intestinal cancer after cholecystectomy: is bile involved in carcinogenesis? Gastroenterology 2001;121(3):542–547.
Ye W, Lagergren J, Nyrén O, Ekbom A. Risk of pancreatic cancer after cholecystectomy: a cohort study in Sweden. Gut 2001;49(5):678–681.
Rosenberg L, Palmer JR, Zauber AG, Warshauer ME, Stolley PD, Shapiro S. Vasectomy and the risk of prostate cancer. Am J Epidemiol 1990;132(6):1051–1055.
Giovannucci E, Tosteson TD, Speizer FE, Ascherio A, Vessey MP, Colditz GA. A retrospective cohort study of vasectomy and prostate cancer in US men. JAMA 1993;269(7):878–882.
Giovannucci E, Ascherio A, Rimm EB, Colditz GA, Stampfer MJ, Willett WC. A prospective cohort study of vasectomy and prostate cancer in US men. JAMA 1993;269(7):873–877.
Lynge E. Prostate cancer is not increased in men with vasectomy in Denmark. J Urol 2002;168(2):488–490.
Daling JR, Malone KE, Voigt LF, White E, Weiss NS. Risk of breast cancer among young women: relationship to induced abortion. J Natl Cancer Inst 1994;86(21):1584–1592.
Rookus MA, van Leeuwen FE. Induced abortion and risk for breast cancer: reporting (recall) bias in a Dutch case-control study. J Natl Cancer Inst 1996;88(23):1759–1764.
Melbye M, Wohlfartht J, Olsen JH, Frisch M, Westergaard T, Helweg-Larsen K, Andersen PK. Induced abortion and the risk of breast cancer. N Engl J Med 1997;336(2):81–85.
Geborek P, Bladström A, Turesson C, Gulfe A, Petersson IF, Saxne T, Olsson H, Jacobsson LT. Tumour necrosis factor blockers do not increase overall tumour risk in patients with rheumatoid arthritis, but may be associated with an increased risk of lymphomas. Ann Rheum Dis 2005;64(5):699–703.
Askling J, Baecklund E, Granath F, Geborek P, Fored M, Backlin C, Bertilsson L, Cöster L, Jacobsson LT, Lindblad S, Lysholm J, Rantapää-Dahlqvist S, Saxne T, van Vollenhoven R, Klareskog L, Feltelius N. Anti-tumour necrosis factor therapy in rheumatoid arthritis and risk of malignant lymphomas: relative risks and time trends in the Swedish Biologics Register. Ann Rheum Dis 2009;68(5):648–653.
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Olsen, J., Christensen, K., Murray, J., Ekbom, A. (2010). Sources of Error in Clinical Epidemiology. In: An Introduction to Epidemiology for Health Professionals. Springer Series on Epidemiology and Public Health, vol 1. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1497-2_23
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DOI: https://doi.org/10.1007/978-1-4419-1497-2_23
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