The Environment and Reproduction: Endocrine Disruption, Reproductive Impairment, and Epigenetics

  • C. Matthew Peterson
  • Douglas T. Carrell
  • Michael Varner
  • Joseph Stanford
  • Mary Croughan
  • Germaine Buck Louis
Chapter

Abstract

This chapter reviews the evidence that environmental factors have a role in the etiology of reproductive abnormalities. The actions of hormonally active agents, such as endocrine disrupting chemicals, that may alter the synthesis, secretion, transport, binding, or elimination of natural hormones are highlighted. This chapter also highlights the need for and organized collection of data to further analyze the involvemnet of environmental factors in reproductive anomalies.

Keywords

Endocrine disruptor Epigenetics Endometriosis Environment Reproductive impairment Biomarkers Chemical substance inventory Chemicals Contaminants 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • C. Matthew Peterson
    • 1
  • Douglas T. Carrell
    • 2
  • Michael Varner
    • 3
  • Joseph Stanford
    • 4
  • Mary Croughan
    • 5
  • Germaine Buck Louis
    • 6
  1. 1.Utah Center for Reproductive Medicine, Department of Obstetrics and GynecologyUniversity of Utah School of MedicineSalt Lake CityUSA
  2. 2.Departments of Surgery (Urology), Obstetrics and Gynecology, and PhysiologyUniversity of Utah School of MedicineSalt Lake CityUSA
  3. 3.Department of Obstetrics and GynecologyUniversity of Utah school of MedicineSalt Lake CityUSA
  4. 4.Department of Family and Preventive MedicineUniversity of Utah Health Sciences CenterSalt Lake CityUSA
  5. 5.Departments of Obstetrics, Gynecology, Reproductive Sciences, and Epidemiology and BiostatisticsUniversity of CaliforniaSan FranciscoUSA
  6. 6.Epidemiology Branch, Division of Epidemiology, Statistics, and Prevention ResearchEunice Kennedy Shriver National Institute of Child Health and Human DevelopmentBethesdaUSA

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