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History of Vaccine Development pp 73–82Cite as

The History of Pertussis Vaccination: From Whole-Cell to Subunit Vaccines

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Abstract

A review of all studies and trials cannot be made in this context, but two sources are recommended, i.e., Whooping cough by Joseph E. Lapin [1] and a review by Fine and Clarkson [2]. In the early years of the twentieth century, attempts were made to develop whole-cell vaccines, but for these early studies, the current definition of vaccination may not be valid since many workers have considered prophylaxis to include preventive treatment in the incubation period of the disease, as noted by Lapin.

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References

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Authors and Affiliations

  1. Department of Clinical Microbiology, Karolinska Hospital, 171 76, Stockholm, Sweden

    Marta Granström

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  1. Marta Granström
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Correspondence to Marta Granström .

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Editors and Affiliations

  1. , Emeritus Professor of Pediatrics, University of Pennsylvania, Philadelphia, 19104, Pennsylvania, USA

    Stanley A. Plotkin

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Granström, M. (2011). The History of Pertussis Vaccination: From Whole-Cell to Subunit Vaccines. In: Plotkin, S. (eds) History of Vaccine Development. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-1339-5_10

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