Abstract
Although a time-resolved near-infrared spectroscopy (TRS) system is difficult to make a measurement into 10 s or less at the moment, the system has a great advantage that it measures absolute values of hemoglobin concentrations. In the present study, using a device equipped with a TRS system, we examined individual differences in changes in cerebral oxygenated, deoxygenated, and total hemoglobin concentrations during two repetitive executions of a cognitive task, and compared these with data from our previous studies performed with a CWS system. As a result, large individual differences were also observed in changes in the cerebral hemoglobin concentrations during a cognitive task in this study using a TRS system. We therefore conclude that large individual differences observed in changes in the cerebral hemoglobin concentrations during a cognitive task in our previous studies using a continuous wave near-infrared spectroscopy (CWS) system would probably be universal, although a CWS system includes the limitation that the absolute value is unable to be measured in the system.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
References
Jöbsis FF (1977) Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. Science 198:1264–1267.
Wyatt JS, Cope M, Delpy DT et al. (1986) Quantification of cerebral oxygenation and haemodynamics in sick newborn infants by near infrared spectrophotometry. Lancet ii:1063–1066.
Chance B, Leigh JS, Miyake H et al. (1988) Comparison of time-resolved and -unresolved measurements of deoxyhemoglobin in brain. Proc Natl Acad Sci USA 85:4971–4975.
Hoshi Y, Tamura M (1993) Detection of dynamic changes in cerebral oxygenation coupled to neuronal function during mental work in man. Neurosci Lett 150:5–8 .
Kato T, Kamei A, Takashima S et al. (1993) Human visual cortical function during photic stimulation monitoring by means of nearinfrared spectroscopy. J Cereb Blood Flow Metab 13:516–520.
Villringer A et al. (1993) Near infrared spectroscopy (NIRS): a new tool to study hemodynamic changes during activation of brain function in human adults. Neurosci Lett 154:101–104.
Niioka T, Chance B (1997) Relative changes in optical path length of near infrared light during a mental task. In: Chance B, Tamura M, Zuo H and Sakatani K (eds.) Non-invasive optical diagnosis: basic science and its clinical application, pp. 3–6. Magazine Office of China-Japan Friendship Hospital, Beijing.
Koizumi H, Yamamoto T, Maki A et al. (2003) Optical topography: practical problems and new applications. Appl Opt 42:3054–3062.
Shiraiwa M, Hasegawa K, Niioka T (2000) Changes in the blood volume and oxygenation in the brain during a mental arithmetic task and their relationships to cardiovascular responses. Ther Res 21:1516–1519.
Niioka T, Shiraiwa M, Hasegawa K (2001) Changes in the regional cerebral blood volume and oxygenation during a mental arithmetic task and their relationships to personality and stress coping traits. Ther Res 22:2004–2007.
Niioka T, Sasaki M (2003) Individual cerebral hemodynamic response to caffeine was related to performance on a newly developed Stroop color-word task. Opt Rev 10:607–608.
Niioka T, Sasaki M (2004) Changes in cerebral hemodynamics during a cognitive task after caffeine ingestion. In: Nakagawa M, Hirata K, Koga Y and Nagata K (ed.) Frontiers in Human Brain Topography, Elsevier B.V., Amsterdam.
Patterson MS, Chance B, Wilson BC (1989) Time resolved reflectance and transmittance for the noninvasive measurement of tissue optical properties. Appl Opt 28:2332–2336.
Oda M, Nakano T, Suzuki A et al. (2000) Near-infrared time-resolved spectroscopy system for tissue oxygenation monitor. Proc SPIE 4160:204–210.
Stroop JR (1935) Studies of interference in serial verbal reactions. J Exp Psychol 18:643–662.
Adleman NE, Menon V, Blasey CM et al. (2002) A developmental fMRI study of the Stroop color-word task. NeuroImage 16:61–75.
Acknowledgment
This work was supported in part by Grant-in-Aid for Scientific Research (19570232).
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2010 Springer Science+Business Media, LLC
About this paper
Cite this paper
Niioka, T., Ohnuki, S., Miyazaki, Y. (2010). Individual Differences in Blood Volume and Oxygenation in the Brain during a Cognitive Task based on Time-Resolved Spectroscopic Measurements. In: Takahashi, E., Bruley, D. (eds) Oxygen Transport to Tissue XXXI. Advances in Experimental Medicine and Biology, vol 662. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1241-1_36
Download citation
DOI: https://doi.org/10.1007/978-1-4419-1241-1_36
Published:
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4419-1239-8
Online ISBN: 978-1-4419-1241-1
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)