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Individual Differences in Blood Volume and Oxygenation in the Brain during a Cognitive Task based on Time-Resolved Spectroscopic Measurements

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Oxygen Transport to Tissue XXXI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 662))

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Abstract

Although a time-resolved near-infrared spectroscopy (TRS) system is difficult to make a measurement into 10 s or less at the moment, the system has a great advantage that it measures absolute values of hemoglobin concentrations. In the present study, using a device equipped with a TRS system, we examined individual differences in changes in cerebral oxygenated, deoxygenated, and total hemoglobin concentrations during two repetitive executions of a cognitive task, and compared these with data from our previous studies performed with a CWS system. As a result, large individual differences were also observed in changes in the cerebral hemoglobin concentrations during a cognitive task in this study using a TRS system. We therefore conclude that large individual differences observed in changes in the cerebral hemoglobin concentrations during a cognitive task in our previous studies using a continuous wave near-infrared spectroscopy (CWS) system would probably be universal, although a CWS system includes the limitation that the absolute value is unable to be measured in the system.

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Acknowledgment

This work was supported in part by Grant-in-Aid for Scientific Research (19570232).

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Correspondence to Tadashi Niioka .

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Niioka, T., Ohnuki, S., Miyazaki, Y. (2010). Individual Differences in Blood Volume and Oxygenation in the Brain during a Cognitive Task based on Time-Resolved Spectroscopic Measurements. In: Takahashi, E., Bruley, D. (eds) Oxygen Transport to Tissue XXXI. Advances in Experimental Medicine and Biology, vol 662. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-1241-1_36

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