Myoglobin and Hemoglobin
Hemoglobin is the vital protein that conveys oxygen from the lungs to the tissues and facilitates the return of carbon dioxide from the tissues back to the lungs –. Myoglobin accepts and stores the oxygen released by hemoglobin and transports it to the mitochondria. The pathways are shown in Fig. 10.1. Together, these two proteins show how protein structure determines function and how Nature uses components, in this case myoglobin, to build more complex proteins consisting of functional subunits. In Part III we explore myoglobin dynamics in more depth; this chapter provides a brief overview of a very complex system and points to why Part III will concentrate on myoglobin rather than hemoglobin.
KeywordsPartial Oxygen Pressure Hill Plot Species Adaptation Binding Curve Functional Subunit
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- 3.J. M. Berg, J. L. Tymoczko, and L. Stryer. Biochemistry, 6th edition. W. H. Freeman, New York, 2006.Google Scholar
- 4.M. F. Perutz. Species adaptation in a protein molecule. Mol. Bio. Evol., 1:1–28, 1983.Google Scholar
- 6.R. E. Dickerson and I. Geis. Hemoglobin. Benjamin/Cumming, Menlo Park, CA, 1983.Google Scholar