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Where Does Campylobacter Come From? A Molecular Odyssey

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Book cover Hot Topics in Infection and Immunity in Children VI

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 659))

Abstract

Campylobacter is the most common bacterial cause of gastroenteritis, worldwide. Since the first description of the disease in the 1970 s (Skirrow, 1977 the incidence of human campylobacteriosis in the UK, measured in terms of laboratory reports, has risen steadily, peaking at 57,674 reports in the year 2000; with 46,603 reports in 2006 (http://www.hpa.org.uk). Although generally self limiting, this disease has an important economic impact (Skirrow and Blaser, 1992). More serious complications, such as motor neurone paralysis, arise in 1–2 cases per 100,000 people in the UK and USA (Nachamkin et al., 1998). The disease also has an appreciable, yet less defined, impact in developing countries. Approximately 90% of human infection is caused by C. jejuni, with C. coli accounting for much of the rest (Gillespie et al., 2002).

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References

  • Adak G.K., Meakins S.M., Yip H., Lopman B.A., & O’Brien S.J. (2005). Disease risks from foods, England and Wales, 1996–2000. Emerg Infect Dis, (11), 365–372.

    PubMed  Google Scholar 

  • Cohan F.M. (2002). What are bacterial species? Annu Rev Microbiol, (56), 457–487.

    Article  PubMed  CAS  Google Scholar 

  • Colles F.M., Jones K., Harding R.M., & Maiden M.C. (2003). Genetic diversity of Campylobacter jejuni isolates from farm animals and the farm environment. Appl Environ Microbiol, (69), 7409–7413.

    Article  PubMed  CAS  Google Scholar 

  • Colles F.M., Jones T.A., McCarthy N.D., Sheppard S.K., Cody A.J., Dingle K.E., Dawkins M.S., & Maiden M.C. (2008). Campylobacter infection of broiler chickens in a free-range environment. Environ Microbiol, (10), 2042–2050.

    Article  PubMed  Google Scholar 

  • Dingle K.E., Colles F.M., Falush D., & Maiden M.C. (2005). Sequence typing and comparison of population biology of Campylobacter coli and Campylobacter jejuni. J Clin Microbiol, (43), 340–347.

    Article  PubMed  CAS  Google Scholar 

  • Dingle K.E., McCarthy N.D., Cody A.J., Peto T.E., & Maiden M.C. (2008). Extended sequence typing of Campylobacter spp. Emerg Infect Dis, (14), 1620–1622.

    Article  PubMed  Google Scholar 

  • Dingle K.E., Colles F.M., Ure R., Wagenaar J., Duim B., Bolton F.J., Fox A.J., Wareing D.R.A., & Maiden M.C.J. (2002). Molecular characterization of Campylobacter jejuni clones: a rational basis for epidemiological investigations. Emerg Infect Dis, (8), 949–955.

    PubMed  CAS  Google Scholar 

  • Dingle K.E., Colles F.M., Wareing D.R.A., Ure R., Fox A.J., Bolton F.J., Bootsma H.J., Willems R.J.L., Urwin R., & Maiden M.C.J. (2001). Multilocus sequence typing system for Campylobacter jejuni. J Clin Microbiol, (39), 14–23.

    Article  PubMed  CAS  Google Scholar 

  • Duim B., Godschalk P.C., van den Braak N. et al. (2003). Molecular evidence for dissemination of unique Campylobacter jejuni clones in Curacao, Netherlands Antilles. J Clin Microbiol, (41), 5593–5597.

    Article  PubMed  CAS  Google Scholar 

  • Eggleston A.K. & West S.C. (1997). Recombination initiation: easy as A, B, C, D... chi? Curr Biol (7), R745–R749.

    Article  PubMed  CAS  Google Scholar 

  • El-Shibiny A., Connerton P.L., & Connerton I.F. (2005). Enumeration and diversity of campylobacters and bacteriophages isolated during the rearing cycles of free-range and organic chickens. Appl Environ Microbiol, (71), 1259–1266.

    Article  PubMed  CAS  Google Scholar 

  • Falush D., Stephens M., & Pritchard J.K. (2003). Inference of population structure using multilocus genotype data: linked loci and correlated allele frequencies. Genetics, (164), 1567–1587.

    PubMed  CAS  Google Scholar 

  • Fraser C., Hanage W.P., & Spratt B.G. (2007). Recombination and the nature of bacterial speciation. Science, (315), 476–480.

    Article  PubMed  CAS  Google Scholar 

  • French N., Barrigas M., Brown P., Ribiero P., Williams N., Leatherbarrow H., Birtles R., Bolton E., Fearnhead P., & Fox A. (2005). Spatial epidemiology and natural population structure of Campylobacter jejuni colonizing a farmland ecosystem. Environ Microbiol, (7), 1116–1126.

    Article  PubMed  CAS  Google Scholar 

  • Gillespie I.A., O’Brien S.J., Frost J.A., Adak G.K., Horby P., Swan A.V., Painter M.J., Neal K.R., & Collaborators C.S.S.S. (2002). A case-case comparison of Campylobacter coli and Campylobacter jejuni infection: a tool for generating hypotheses. Emerg Infect Dis, (8), 937–942.

    PubMed  Google Scholar 

  • Grant P.R. & Grant B.R. (1992). Hybridization of bird species. Science, (256), 193–197.

    Article  PubMed  CAS  Google Scholar 

  • Gupta S. & Maiden M.C.J. (2001). Exploring the evolution of diversity in pathogen populations. Trends Microbiol, (9), 181–192.

    Article  PubMed  CAS  Google Scholar 

  • Hanage W.P., Spratt B.G., Turner K.M., & Fraser C. (2006). Modelling bacterial speciation. Phil Trans Roy Soc Lond B Biol Sci (361), 2039–2044.

    Article  Google Scholar 

  • Holmes E.C., Urwin R., & Maiden M.C.J. (1999). The influence of recombination on the population structure and evolution of the human pathogen Neisseria meningitidis. Mol Biol Evol, (16), 741–749.

    PubMed  CAS  Google Scholar 

  • Hopkins R.S., Olmsted R., & Istre G.R. (1984). Endemic Campylobacter jejuni infection in Colorado: identified risk factors. Am J Pub Health, (74), 249–250.

    Article  CAS  Google Scholar 

  • Humphrey T. (2006). Are happy chickens safer chickens? Poultry welfare and disease susceptibility. Br Poult Sci, (47), 379–391.

    Article  PubMed  Google Scholar 

  • Humphrey T.J. (1989). An appraisal of the efficacy of pre-enrichment for the isolation of Campylobacter jejuni from water and food. J Appl Bacteriol, (66), 119–126.

    PubMed  CAS  Google Scholar 

  • Ketley J.M. (1997). Pathogenesis of enteric infection by Campylobacter. Microbiology, (143), 5–21.

    Article  PubMed  CAS  Google Scholar 

  • Lawrence J.G. (2002). Gene transfer in bacteria: speciation without species? Theor Popul Biol, (61), 449–460.

    Article  PubMed  Google Scholar 

  • Lindqvist R. & Lindblad M. (2008). Quantitative risk assessment of thermophilic Campylobacter spp. and cross-contamination during handling of raw broiler chickens evaluating strategies at the producer level to reduce human campylobacteriosis in Sweden. Int J Food Microbiol (121), 41–52.

    Article  PubMed  Google Scholar 

  • Maiden M.C. (2006). Multilocus sequence typing of bacteria. Annu Rev Microbiol, (60), 561–588.

    Article  PubMed  CAS  Google Scholar 

  • Mallet J. (2007). Hybrid speciation. Nature, (446), 279–283.

    Article  PubMed  CAS  Google Scholar 

  • Mickan L., Doyle R., Valcanis M., Dingle K.E., Unicomb L., & Lanser J. (2007). Multilocus sequence typing of Campylobacter jejuni isolates from New South Wales, Australia. J Appl Microbiol, (102), 144–152.

    Article  PubMed  CAS  Google Scholar 

  • Nachamkin I., Allos B.M., & Ho T. (1998). Campylobacter species and Guillain-Barré syndrome. Clin Microbiol Rev, (11), 555–567.

    PubMed  CAS  Google Scholar 

  • Newell D.G. & Fearnley C. (2003). Sources of Campylobacter colonization in broiler chickens. Appl Environ Microbiol, (69), 4343–4351.

    Article  PubMed  CAS  Google Scholar 

  • Parkhill J., Wren B.W., Mungall K. et al. (2000). The genome sequence of the food-borne pathogen Campylobacter jejuni reveals hypervariable sequences. Nature, (403), 665–668.

    Article  PubMed  CAS  Google Scholar 

  • Peabody R., Ryan M.J., & Wall P.G. (1997). Outbreaks of Campylobacter infection: rare events for a common pathogen. CDR, (7), R33–R37.

    Google Scholar 

  • Penner J.L., Hennessy J.N., & Congi R.V. (1983). Serotyping of Campylobacter jejuni and Campylobacter coli on the basis of thermostable antigens. Eur J Clin Microbiol, (2), 378–383.

    Article  PubMed  CAS  Google Scholar 

  • Sheppard S.K., McCarthy N.D., Falush D., & Maiden M.C. (2008). Convergence of Campylobacter species: implications for bacterial evolution. Science, (320), 237–239.

    Article  PubMed  CAS  Google Scholar 

  • Skirrow M.B. (1977). Campylobacter enteritis: a “new” disease. BMJ, (2), 9–11.

    Article  PubMed  CAS  Google Scholar 

  • Skirrow M.B. & Blaser M.J. (1992). Clinical and Epidemiological Considerations. Tompkins LS (Ed.), pp. 3–8. Washington, DC: American Society for Microbiology.

    Google Scholar 

  • Sopwith W., Birtles A., Matthews M., Fox A., Gee S., Painter M., Regan M., Syed Q., & Bolton E. (2006). Campylobacter jejuni multilocus sequence types in humans, northwest England, 2003–2004. Emerg Infect Dis, (12), 1500–1507.

    PubMed  CAS  Google Scholar 

  • Wareing D.R., Ure R., Colles F.M., Bolton F.J., Fox A.J., Maiden M.C., & Dingle K.E. (2003). Reference isolates for the clonal complexes of Campylobacter jejuni. Lett Appl Microbiol, (36), 106–110.

    Article  PubMed  CAS  Google Scholar 

  • Young K.T., Davis L.M., & Dirita V.J. (2007). Campylobacter jejuni: molecular biology and pathogenesis. Nat Rev Microbiol, (5), 665–679.

    Article  PubMed  CAS  Google Scholar 

  • Zhu P., van der Ende A., Falush D. et al. (2001). Fit genotypes and escape variants of subgroup III Neisseria meningitidis during three pandemics of epidemic meningitis. Proc Natl Acad Sci USA, (98), 5234–5239.

    Article  PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Zoology, University of Oxford, South Parks Road, OX1 2PS, Oxford, UK

    Alison J. Cody, Frances M. Colles, Samuel K. Sheppard & Martin C.J. Maiden

Authors
  1. Alison J. Cody
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  2. Frances M. Colles
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  3. Samuel K. Sheppard
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  4. Martin C.J. Maiden
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Corresponding author

Correspondence to Martin C.J. Maiden .

Editor information

Editors and Affiliations

  1. Institute of Child Life and Health, University of Bristol, Upper Maudlin Street, Bristol, BS2 8AE, United Kingdom

    Adam Finn

  2. Royal Children's Hosp., University of Melbourne, Parkville , 3052, Australia

    Nigel Curtis

  3. University of Oxford, Level 4,John Radcliffe Hospital, Oxford, OX3 9DU, United Kingdom

    Andrew J. Pollard

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Cody, A.J., Colles, F.M., Sheppard, S.K., Maiden, M.C. (2010). Where Does Campylobacter Come From? A Molecular Odyssey. In: Finn, A., Curtis, N., Pollard, A. (eds) Hot Topics in Infection and Immunity in Children VI. Advances in Experimental Medicine and Biology, vol 659. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0981-7_4

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