Skip to main content

Imaging of Asthma in Children

  • Chapter
  • First Online:
Evidence-Based Imaging in Pediatrics
  • 1536 Accesses

Key Points

■ Airway inflammation is universal to all asthmatics and the degree of the inflammation corresponds to the severity of disease. Bronchoconstriction plays a limited role in the etiology of asthma (moderate evidence).

■ There has been a sharp rise in the prevalence, morbidity, mortality, and economic burden both within the United States and globally over the past 40 years, particularly in children (moderate evidence).

■ Despite the considerable knowledge with regard to the pathology of asthma, the costs of asthma represent a large burden to society, both nationally and internationally (moderate evidence).

■ The majority of patients presenting with asthma can be diagnosed clinically by medical history and physical examination; the need for chest radiographs in acute asthma is limited to a minority of patients (limited to moderate evidence).

■ Pulmonary function testing underestimates the degree of bronchial inflammation and may be insufficient for surveillance criteria (limited evidence).

■ No data were found in the medical literature that evaluate the cost-effectiveness of imaging in asthma (insufficient evidence).

■ The value of the chest radiograph should be to diagnose complications, to establish a precipitating cause for an asthmatic attack, and to exclude alternate diagnoses that resemble asthma (moderate evidence).

■ High-resolution computed tomography (HRCT) is a non-invasive technique capable of demonstrating and quantifying both the anatomic and physiologic changes in the lungs of asthmatic patients (moderate evidence).

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 84.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 109.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Osler W. The Principles and Practice of Medicine. New York: D Appleton and Company, 1892.

    Google Scholar 

  2. Warner JO, Naspitz CK. Pediatr Pulmonol 1998 Jan; 25(1):1–17. Review.

    Article  CAS  PubMed  Google Scholar 

  3. National Asthma Education and Prevention Program. Expert Panel Report 2: Guidelines for the Diagnosis and Management of Asthma. National Institutes of Health Publication No. 97-4051. Bethesda, MD, 1997.

    Google Scholar 

  4. National Asthma Education and Prevention Program. Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma. National Institutes of Health Publication No. 91-3642. Bethesda, MD, 1991.

    Google Scholar 

  5. Willis-Karp M. Annu Rev Immunol 1999; 17:255–281. Review.

    Article  Google Scholar 

  6. Bramam SS. Chest 2006 Jul; 130(1 Suppl):4S–12S. Review.

    Article  Google Scholar 

  7. Masoli M, Fabian D, Holt S et al. Allergy 2004; 59:469–478.

    Article  PubMed  Google Scholar 

  8. From the Centers of Disease Control and Prevention. MMWR Morb Mortal Wkly Rep 2000; 49(40):908–911.

    Google Scholar 

  9. Akinbami LJ, Schoendorf KC, Parker J. Am J Epidemiol 2003; 158(2):99–104.

    Article  PubMed  Google Scholar 

  10. From the Centers for Disease Control and Prevention. JAMA 2000; 284(18):2312–2313.

    Article  Google Scholar 

  11. Akinbami L. Adv Data 2006 Dec 12;(381):1–24.

    Google Scholar 

  12. Mannino DM, Homa DM, Pertowski CA et al. MMWR CDC Surveill Summ 1998; 47(1):1–27.

    CAS  Google Scholar 

  13. Akinbami LJ, Schoendorf KC. Pediatrics 2002 Aug; 110(2 Pt 1):315–322.

    Article  PubMed  Google Scholar 

  14. Weiss KB, Sullivan SD. J Allergy Clin Immunol 2001; 107:3–8.

    Article  CAS  PubMed  Google Scholar 

  15. Weiss KB, Sullivan SD. J Allergy Clin Immunol Sept 2000.

    Google Scholar 

  16. Stanford R, McLaughlin T, Okamoto LJ. Am J Respir Crit Care Med 1999; 160:211–215.

    CAS  PubMed  Google Scholar 

  17. Malone DC, Lawson KA, Smith DH. Pharm Pract Manage Q 2000; 20:12–20.

    CAS  Google Scholar 

  18. Smith DH, Malone DC, Lawson KA et al. Am J Respir Crit Care Med 1997; 156:787–793.

    CAS  PubMed  Google Scholar 

  19. Buckmaster A, Boon R. J Paediatr Child Health 2005 Mar; 41(3):107–111.

    Article  CAS  PubMed  Google Scholar 

  20. Alford BA, Armstrong P. Curr Probl Diagn Radiol 1983 May–Jun ; 12(3):1–38.

    Article  CAS  PubMed  Google Scholar 

  21. Royle H. Br Med J 1952 Mar 15; 1(4758):577–580.

    Article  CAS  PubMed  Google Scholar 

  22. Richards W, Patrick JR. Am J Dis Child 1965 Jul; 110:4–23.

    CAS  PubMed  Google Scholar 

  23. Dworetsky M, Philson AD. J Allergy 1968 Apr; 41(4):181–194.

    Article  Google Scholar 

  24. Simon G. In: Principles of Chest X-ray Diagnosis, 3rd ed. London: Butterworths.

    Google Scholar 

  25. Rebuck AS. Australas Radiol 1970 Aug; 14(3):264–268.

    Article  CAS  PubMed  Google Scholar 

  26. Simon G, Connolly N, Littlejohns DW et al. Thorax 1973 Mar; 28(2):115–123.

    Article  CAS  PubMed  Google Scholar 

  27. Hodson ME, Simon G, Batten JC. Thorax 1974 May; 29(3):296–303.

    Article  CAS  PubMed  Google Scholar 

  28. Eggleston PA, Ward BH, Pierson WE et al. Pediatrics 1974 Oct; 54(4):442–449.

    CAS  PubMed  Google Scholar 

  29. Gillies JD, Reed MH, Simons FE. Can Assoc Radiol 1978 Mar; 29(1):28–33.

    CAS  Google Scholar 

  30. Gillies JD, Reed MH, Simons FE. J Can Assoc Radiol 1980 Mar; 31(1):45–47.

    CAS  PubMed  Google Scholar 

  31. Brooks LJ, Cloutier MM, Afshani E. Chest 1982 Sep; 82(3):315–318.

    Article  CAS  PubMed  Google Scholar 

  32. Rushton AR. Clin Pediatr (Phila) 1982 Jun ; 21(6):325–328.

    Article  CAS  Google Scholar 

  33. Zieverink SE, Harper AP, Holden RW et al. Radiology 1982 Oct; 145(1):27–29.

    CAS  PubMed  Google Scholar 

  34. Gershel JC, Goldman HS, Stein RE et al. N Engl J Med 1983 Aug 11; 309(6):336–339.

    Article  CAS  PubMed  Google Scholar 

  35. Dalton AM. Arch Emerg Med 1991 Mar; 8(1):36–40.

    CAS  PubMed  Google Scholar 

  36. Dawson KP, Capaldi N. Aust Clin Rev 1993; 13(4):153–156.

    CAS  PubMed  Google Scholar 

  37. Ismail Y, Loo CS, Zahary MK. Singapore Med J 1994 Apr; 35(2):171–172.

    Google Scholar 

  38. Tsai SL, Crain EF, Silver EJ et al. Pediatr Radiol 2002 Jul; 32(7):498–504. Epub 2002 Mar 29.

    Article  PubMed  Google Scholar 

  39. Hederos CA, Janson S, Andersson JS et al. Pediatr Allergy Immunol 2004 Apr; 15(2):163–165.

    Article  PubMed  Google Scholar 

  40. Blair DN, Coppage L, Shaw C. J Thorac Imaging 1986 Mar; 1(2):23–35.

    Article  CAS  PubMed  Google Scholar 

  41. Joregensen JR, Falliers CJ, Bukantz SC. Pediatrics 1963 May; 31:824–832.

    Google Scholar 

  42. Zulkifli A, Kamal AA. Med J Malaysia 1980 Dec; 35(2):164–165.

    CAS  PubMed  Google Scholar 

  43. Bierman CW. Am J Dis Child 1967 Jul; 114(1):42–50.

    CAS  PubMed  Google Scholar 

  44. Jensen SP, Lynch DA, Brown KK et al. Clin Radiol 2002 Dec; 57(12):1078–1085.

    Article  CAS  PubMed  Google Scholar 

  45. Silva CI, Colby TV, Muller NL. Am J Roentgenol 2004 Sep; 183(3):817–824.

    Google Scholar 

  46. Stern EJ, Frank MS. AJR Am J Roentgenol 1994 Jul; 163(1):37–41.

    CAS  PubMed  Google Scholar 

  47. Ketai L, Coutsias C, Williamson S et al. Acad Radiol 2001 Mar; 8(3):257–264.

    Article  CAS  PubMed  Google Scholar 

  48. Goldin JG, McNitt-Gray MF, Sorenson SM et al. Radiology 1998 Aug; 208(2):321–329.

    CAS  PubMed  Google Scholar 

  49. Nuhoglu Y, Bahceciler N, Yuksel M et al. Ann Allergy Asthma Immunol 1999 Mar; 82(3):311–314.

    Article  CAS  PubMed  Google Scholar 

  50. Pifferi M, Caramella D, Ragazzo V et al. J Pediatr 2002 Jul; 141(1):104–108.

    Article  PubMed  Google Scholar 

  51. Marchac V, Emond S, Mamou-Mani T et al. Am J Roentgenol 2002 Nov; 179(5):1245–1252.

    Google Scholar 

  52. de Blic J, Tillie-Leblond I, Emond S et al. J Allergy Clin Immunol 2005 Oct; 116(4):750–754.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2010 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Bates, D.G. (2010). Imaging of Asthma in Children. In: Medina, L., Applegate, K., Blackmore, C. (eds) Evidence-Based Imaging in Pediatrics. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0922-0_28

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-0922-0_28

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0921-3

  • Online ISBN: 978-1-4419-0922-0

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics