Skip to main content

Pacemakers and Implantable Cardioverter Defibrillators in the Elderly

  • Chapter
  • First Online:
Cardiothoracic Surgery in the Elderly

Abstract

Permanent pacemakers, implantable cardioverter defibrillators (ICDs) and cardiac resynchronization (CRT) devices are commonly used in the management of cardiovascular disease. Sick sinus syndrome and atrio-ventricular block are the two most common indications for permanent pacemaker implantation, representing more than 90% of the cases, and are both strongly associated with increasing age. Understanding the cardiovascular physiology among elderly patients is critical to the selection of the optimal surgical technique and reduction of complications. In this chapter, the role of pacemakers, ICDs, CRTs as well as technical issues for cardiac rhythm device implantation, including risk of device-related complications and appropriate programming in elderly patients, is discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 169.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 249.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Healey JS, Toff WD, Lamas GA, et al. Cardiovascular outcomes with atrial-based pacing compared with ventricular pacing: meta-analysis of randomized trials, using individual patient data. Circulation. 2006;114(1):11–7.

    Article  PubMed  Google Scholar 

  2. Bristow MR, Saxon LA, Boehmer J, et al. Cardiac-resynchronization therapy with or without an implantable defibrillator in advanced chronic heart failure. N Engl J Med. 2004;350:2140–50.

    Article  PubMed  CAS  Google Scholar 

  3. Moss AJ, Zareba W, Hall WJ, et al. Prophylactic implantation of a defibrillator in patients with myocardial infarction and reduced ejection fraction. N Engl J Med. 2002;346(12):877–83.

    Article  PubMed  Google Scholar 

  4. Cleland JG, Daubert J-C, Erdmann E, et al. The effect of cardiac resynchronization on morbidity and mortalilty in heart failure. N Engl J Med. 2005;352:1539–49.

    Article  PubMed  CAS  Google Scholar 

  5. Curtis JP, Rathore SS, Wang Y, et al. The association of 6-minute walk performance and outcomes in stable outpatients with heart failure. J Card Fail. 2004;10:9–14.

    PubMed  Google Scholar 

  6. Aggarwal A, Wang Y, Rumsfeld JS, Curtis JP, Heidenreich PA. Clinical characteristics and in-hospital outcome of patients with end-stage renal disease on dialysis referred for implantable cardioverter defibrillator implantation. Heart Rhythm. 2009;6(11): 1565–71.

    Article  PubMed  Google Scholar 

  7. Bernstein AD, Parsonnet V. Survey of cardiac pacing and defibrillation in the United States in 1993. Am J Cardiol. 1996;78:187–96.

    Article  PubMed  CAS  Google Scholar 

  8. Kozak LJ, Owings MF, Hall MJ. National Hospital Discharge Survey: 2002 annual summary with detailed diagnosis and procedure data. Vital Health Stat. 2005;13(158):1–199.

    Google Scholar 

  9. Healey J, Connolly SJ, Morillo CA. The management of patients with carotid sinus hypersensitivity: is pacing the answer? Clin Auton Res. 2004;14 Suppl 1:80–6.

    Article  PubMed  Google Scholar 

  10. McIntosh S, da Costa D, Kenny RA. Benefits of an integrated approach to the investigation of dizziness, falls and syncope in the elderly. Age Ageing. 1993;22:53–8.

    Article  PubMed  CAS  Google Scholar 

  11. Lamas GA, Orav J, Stambler BS, et al. Quality of life and clinical outcomes in elderly patients treated with ventricular pacing as ­compared with dual-chamber pacing. N Engl J Med. 1998;338:1097–104.

    Article  PubMed  CAS  Google Scholar 

  12. Toff WD, Camm AJ, Skehan JD. Single-chamber versus dual-chamber pacing for high-grade atrioventricular block. N Engl J Med. 2005;353(2):145–55.

    Article  PubMed  CAS  Google Scholar 

  13. Bardy GH, Lee KL, Mark DB, et al. Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. N Engl J Med. 2005;352:225–37.

    Article  PubMed  CAS  Google Scholar 

  14. Huang DT, Sesselberg HW, McNItt S, et al. Improved survival associated with prophylactic implantable defibrillators in elderly patients with prior myocardial infarction and depressed ventricular function: a MADIT-II substudy. J Cardiovasc Electrophysiol. 2007;18(8):833–8.

    Article  PubMed  Google Scholar 

  15. Peterson PN, Daugherty SL, Wang Y, et al. Gender differences in procedure-related adverse events in patients receiving implantable cardioverter-defibrillator therapy. Circulation. 2009;119(8):1078–84.

    Article  PubMed  Google Scholar 

  16. Bradley DJ, Bradley EA, Baughman KL, et al. Cardiac resynchronization and death from progressive heart failure: a meta-analysis of randomized controlled trials. JAMA. 2003;289:730–40.

    Article  PubMed  Google Scholar 

  17. Birnie D, Wiliams K, Guo A, et al. Reasons for escalating pacemaker implants. Am J Cardiol. 2006;98(1):93–7.

    Article  PubMed  Google Scholar 

  18. Shen WK, Hammill SC, Hayes DL, et al. Long-term survival after pacemaker implantation for heart block in patients >65 years. Am J Cardiol. 1994;74(6):560–4.

    Article  PubMed  CAS  Google Scholar 

  19. Sutton R, Chatterjee K, Leatham A. Heart-block following acute myocardial infarction. Treatment with demand and fixed-rate ­pacemakers. Lancet. 1968;2(7569):645–8.

    Article  PubMed  CAS  Google Scholar 

  20. Alpert MA, Curtis JJ, Sanfelippo JF, et al. Comparative survival after permanent ventricular and dual chamber pacing for patients with chronic high degree atrioventricular block with and without pre-existing congestive heart failure. J Am Coll Cardiol. 1986;7:925–32.

    Article  PubMed  CAS  Google Scholar 

  21. Shen WK, Hayes DL, Hammill SC, Bailey KR, Ballard DJ, Gersh BJ. Survival and functional independence after implantation of a permanent pacemaker in octogenarians and nonagenarians. A population-based study. Ann Intern Med. 1996;125(6):476–80.

    PubMed  CAS  Google Scholar 

  22. Lipsitz LA, Wei JY, Rowe JW. Syncope in elderly, institutionalized population: prevalence, incidence and associated risk. Q J Med. 1985;55:45–55.

    PubMed  CAS  Google Scholar 

  23. Hale WA, Delaney MJ, McGaghie WC. Characteristics and predictors of falls in elderly patients. J Fam Pract. 1992;34:577–81.

    PubMed  CAS  Google Scholar 

  24. O¢Laughlin JL, Robitaille Y, Boivin JF, Suissa S. Incidence and risk factors for falls and injurious falls among the community-dwelling elderly. Am J Epidemiol. 1993;137:342–5.

    Google Scholar 

  25. Parry SW, Baptist M, Kenny R-A. Drop attacks in older adults: ­systematic assesment has high diagnostic yield. J Am Geriatr Soc. 2005;53:74–8.

    Article  PubMed  Google Scholar 

  26. McIntosh SJ, Lawson J, Kenny RA. Clinical characteristics of vasodepressor, cardioinhibitory and mixed carotid sinus syndrome in the elderly. Am J Med. 1993;95:203–8.

    Article  PubMed  CAS  Google Scholar 

  27. Crilley JG, Herd B, Khurana CS, et al. Permanent cardiac pacing in elderly patients with recurrent falls, dizziness and syncope and a hypersensitive cardioinhibitory reflex. Postgrad Med J. 1997;73: 415–8.

    Article  PubMed  CAS  Google Scholar 

  28. Davies AJ, Kenny RA. Falls presenting to the accident and emergency department: types of presentation and risk factor profile. Ageing. 1996;25:362–5.

    CAS  Google Scholar 

  29. Parry SW, Richardson D, O'Shea D, et al. Diagnosis of carotid hypersensitivity in older adults: carotid sinus massage in the upright position is essential. Heart. 2000;83:22–3.

    Article  PubMed  CAS  Google Scholar 

  30. Parry SW, Steen IN, Baptist M, et al. Amnesia for loss of consciousness in patients with carotid sinus syndrome. J Am Coll Cardiol. 2005;45:1840–3.

    Article  PubMed  Google Scholar 

  31. Kenny RA, Richardson DA, Steen N, et al. Carotid sinus syndrome: a modifiable risk factor for non-accidental falls in older adults (SAFE PACE). J Am Coll Cardiol. 2001;38:1491–6.

    Article  PubMed  CAS  Google Scholar 

  32. Richardson DA, Bexton RS, Shaw FE, Kenny R-A. Prevalence of cardio-inhibitory carotid sinus hypersensitivity in patients 50 years or over presenting to the accident and emergency department with “unexplained” or “recurrent” falls. Pacing Clin Electrophysiol. 1997;3(2):820–3.

    Article  Google Scholar 

  33. Morley CA, Perrins EJ, Grant P, et al. Carotid sinus syncope treated by pacing. Analysis of persistent symptoms and role of atrioventricular sequential pacing. Br Heart J. 1982;47:411–8.

    Article  PubMed  CAS  Google Scholar 

  34. Fitzpatrick A, Theodorakis G, Ahmed R, Williams T, Sutton R. Dual chamber pacing aborts vasovagal syncope induced by head-up tilt. Pacing Clin Electrophysiol. 1991;4:13–9.

    Article  Google Scholar 

  35. Brignole M, Menozzi C, Lolli G, Oddone D, Gianfranchi L, Bertulla A. Validation of a method of pacing mode in carotid sinus syndrome with or without sinus bradycardia. Pacing Clin Electrophysiol. 1991;14:196–203.

    Article  PubMed  CAS  Google Scholar 

  36. Brignole M, Menozzi C, Lolli G, Bottoni N, Gagglioli G. Long-term outcome of paced and nonpaced patients with severe carotid sinus syndrome. Am J Cardiol. 1992;69:1039–43.

    Article  PubMed  CAS  Google Scholar 

  37. McAnulty J. Carotid sinus massage in patients who fall: will it define the role of pacing? J Am Coll Cardiol. 2001;38:1497.

    Article  PubMed  CAS  Google Scholar 

  38. Parry SW, Steen N, Bexton RS, Tynan M, Kenny R-A. Pacing in elderly recurrent fallers with carotid sinus hypersenstivity: a randomised, double-blind, placebo controlled crossover trial. Heart. 2009;95(5):405–9.

    Article  PubMed  CAS  Google Scholar 

  39. Sheldon R. Components of clinical trials for vasovagal syncope. Europace. 2001;3:233–40.

    Article  PubMed  CAS  Google Scholar 

  40. Connolly SJ, Sheldon R, Roberts RS, Gent M. The North American vasovagal pacemaker study (VPS): a randomized trial of permanent cardiac pacing for the prevention of vasovagal syncope. J Am Coll Cardiol. 1999;33(1):16–20.

    Article  PubMed  CAS  Google Scholar 

  41. Connolly SJ, Sheldon R, Thorpe KE, et al. Pacemaker therapy for prevention of syncope in patients with recurrent severe vasovagal syncope: second vasovagal pacemaker study (VPS II): a randomized trial. JAMA. 2003;289(17):2224–9.

    Article  PubMed  Google Scholar 

  42. Ammirati F, Colivicchi F, Santini M. Permanent cardiac pacing ­versus medical treatment for the prevention of recurrent vasovagal syncope: a multi-centre, randomized-controlled trial. Circulation. 2001;104:52–7.

    Article  PubMed  CAS  Google Scholar 

  43. Sutton R, Brignole M, Menozzi C, et al. The vasovagal syncope international study (VASIS) investigators. Dual-chamber pacing in the treatment of neurally mediated tilt-positive cardioinhibitory syncope: pacemaker versus no therapy: a multi-centre randomized study. Circulation. 2000;102:294–9.

    Article  PubMed  CAS  Google Scholar 

  44. Raviele A, Giada F, Menozzi C, et al. A randomized, double-blind, placebo-controlled study of permanent cardiac pacing for the treatment of recurrent tilt-induce vasovagal syncope. The vasovagal syncope and pacing trial (SYNPACE). Eur Heart J. 2004;25:1741–8.

    Article  PubMed  Google Scholar 

  45. Aggarwal RK, Connelly DT, Ray SG, Ball J, Charles RB. Early complications of permanent pacemaker implantation: no difference between dual and single chamber systems. Br Heart J. 1995;73: 571–5.

    Article  PubMed  CAS  Google Scholar 

  46. Chauhan A, Grace AA, Newell SA, et al. Early complications after dual-chamber versus single chamber pacemaker implantation. Pacing Clin Electrophysiol. 1994;17:2012–5.

    Article  PubMed  CAS  Google Scholar 

  47. Lee DS, Birinie D, Cameron D, et al. Design and implementation of a population-based registry of implantable cardioverter defibrillators (ICDs) in Ontario. Heart Rhythm. 2008;5(9):1250–6.

    Article  PubMed  Google Scholar 

  48. Curtis JP, Leubbert JJ, Wang Y, et al. Association of physician certification and outcomes among patients receiving an implantable cardioverter-defibrillator. JAMA. 2009;301(16):1661–70.

    Article  PubMed  CAS  Google Scholar 

  49. Pickett 3rd RA, Saavedra P, Ali MF, Darbar D, Rottman JN. Implantable cardioverter-defibrillator malfunction due to mechanical failure of the header connection. J Cardiovasc Electrophysiol. 2004;15(9):1095–9.

    Article  PubMed  Google Scholar 

  50. Gillis AM, MacQuarrie DS, Wilson SL. The impact of pulse generator longevity on the long-term costs of cardiac pacing. Pacing Clin Electrophysiol. 1996;19:1459–68.

    Article  PubMed  CAS  Google Scholar 

  51. Rusanov A, Spotnitz HM. A 15-year experience with permanent pacemaker and defibrillator lead and patch extractions. Ann Thorac Surg. 2010;89(1):44–50.

    Article  PubMed  Google Scholar 

  52. Mahapatra S, Bybee KA, Bunch TJ, et al. Incidence and predictors of cardiac perforation after permanent pacemaker placement. Heart Rhythm. 2005;2(9):907–11.

    Article  PubMed  Google Scholar 

  53. Connolly SJ, Hallstrom AP, Cappato R, et al. Meta-analysis of the implantable cardioverter defibrillator secondary prevention trials. Eur Heart J. 2000;21:2071–8.

    Article  PubMed  CAS  Google Scholar 

  54. Sanders GD, Hlatky MA, Owens DK. Cost-effectiveness of implantable cardioverter-defibrillators. N Engl J Med. 2005;353:1471–80.

    Article  PubMed  CAS  Google Scholar 

  55. Mark DB, Anstrom KJ, Sun JL, et al. Quality of life with defibrillator therapy or amiodarone in heart failure. N Engl J Med. 2008;359(10):1058–9.

    Article  Google Scholar 

  56. Poole JE, Johnson GW, Hellkamp AS, et al. Prognostic importance of defibrillator shocks in the sudden cardiac death in heart failure trial. N Engl J Med. 2008;359:1009–17.

    Article  PubMed  CAS  Google Scholar 

  57. Healey JS, Hallstrom AP, Kuck KH, et al. Role of the implantable defibrillator in elderly patients with a history of life-threatening ventricular arrhythmias. Eur Heart J. 2008;28(14):174–1749.

    Google Scholar 

  58. Krahn A, Connolly SJ, Roberts RS, Gent M, ATMA Investigators. Diminishing proportional risk of sudden death with advancing age: implications for prevention of sudden death. Am Heart J. 2004;147(5):837–40.

    Article  PubMed  Google Scholar 

  59. Duray G, Richter S, Manegold J, Israel CW, Gronefeld G, Hohnloser SH. Efficacy and safety of ICD therapy in a population of elderly patients treated with optimal background medication. J Interv Card Electrophysiol. 2005;14:169–73.

    Article  PubMed  Google Scholar 

  60. Kleman JM, Pinski SL, Morant VA. ICDs in the very elderly: short and long-term outcome. Pacing Clin Electrophysiol. 1994;17:835.

    Article  Google Scholar 

  61. Noseworthy PA, Lashevsky I, Dorian P, Greene M, Cvitkovic S, Newman D. Feasibility of implantable cardioverter-defibrillator use in elderly patients. Pacing Clin Electrophysiol. 2004;27:373–8.

    Article  PubMed  Google Scholar 

  62. Feinberg WM, Blackshear JL, Laupacis A, Kronmal R, Hart RG. Prevalence, age distribution and gender of patients with atrial ­fibrillation: analysis and implications. Arch Intern Med. 1995;155:469–73.

    Article  PubMed  CAS  Google Scholar 

  63. Baranchuk A, Healey JS, Thorpe KE, et al. The effect of atrial-based pacing on exercise capacity as measured by the 6-minute walk test: a sub-study of the Canadian trial of physiologic pacing (CTOPP). Heart Rhythm. 2007;4(8):1024–8.

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Luciana Armaganijan .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2011 Springer Science+Business Media, LLC

About this chapter

Cite this chapter

Armaganijan, L., Healey, J.S. (2011). Pacemakers and Implantable Cardioverter Defibrillators in the Elderly. In: Katlic, M. (eds) Cardiothoracic Surgery in the Elderly. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0892-6_35

Download citation

  • DOI: https://doi.org/10.1007/978-1-4419-0892-6_35

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4419-0891-9

  • Online ISBN: 978-1-4419-0892-6

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics