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Narcolepsy pp 99–103Cite as

REM Sleep Behavior Disorder in Narcolepsy with Cataplexy

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Abstract

Narcolepsy with cataplexy (NC) is a chronic disease characterized by excessive daytime sleepiness, striking transitions from wakefulness into rapid eye movement (REM) sleep, typically associated with cataplexy and other phenomena due to the abnormal occurrence of REM sleep elements during wakefulness (sleep paralysis and hallucinations) and frequent sleep/wake transitions. Nocturnal sleep in NC is usually disturbed by a large cohort of phenomena: vivid frightening dreams, several nocturnal awakenings, REM sleep behavior disorder (RBD), periodic leg movement (PLM), obstructive sleep apnea (OSA), sleep-related eating disorders and other parasomnias. Several clinical and polysomnographic aspects seem to differentiate RBD in patients with narcolepsy from idiopathic or secondary RBD, suggesting the involvement of specific neurophysiological, neurochemical and neuropathological substrates.

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Author information

Authors and Affiliations

  1. Dipartimento di Scienze Neurologiche, Università di Bologna, Via Ugo Foscolo 7, 40123, Bologna, Italy

    Giuseppe Plazzi

Authors
  1. Giuseppe Plazzi
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  2. Yves Dauvilliers
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Corresponding author

Correspondence to Giuseppe Plazzi .

Editor information

Editors and Affiliations

  1. Narcolepsy Institute, Montefiore Medical Center, East 210 Street 111, Bronx, 10467, U.S.A.

    Meeta Goswami

  2. Dept. Pharmacology, Columbia University, West 168th St. 630, New York, 10032, U.S.A.

    S. R. Pandi-Perumal

  3. Sleep-Wake Disorders Center, Montefiore Hospital, East 210th Street 111, Bronx, 10467, U.S.A.

    Michael J. Thorpy

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Plazzi, G., Dauvilliers, Y. (2010). REM Sleep Behavior Disorder in Narcolepsy with Cataplexy. In: Goswami, M., Pandi-Perumal, S., Thorpy, M. (eds) Narcolepsy. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-0854-4_9

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  • DOI: https://doi.org/10.1007/978-1-4419-0854-4_9

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  • Online ISBN: 978-1-4419-0854-4

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