Abstract
Can functional vision be restored in blind human subjects using a microelectronic retinal prosthesis? The initial indications suggest that, yes, it is possible. However, the visual experience of these subjects is nothing like a digital scoreboard-like movie, with each electrode acting as an independent pixel. The work described here in this chapter suggests that there are interactions between pulses and across electrodes, at the electrical, retinal, or even cortical level that influence the quality of the percept. In particular, this work addresses the question, “how does the percept change as a function of pulse timing on single and multiple electrodes”? The motivation for the work described here is that these interactions must be understood and predictable if we are to develop a functional tool for blind human patients. In this chapter, we review work evaluating perceptual effects using chronic electric stimulation in three different implantable systems.
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- AltFC:
-
Alternative forced-choice
- AMD:
-
Age-related macular degeneration
- BLP:
-
Bare light perception
- ChR2:
-
Channelrhodopsin-2
- DS:
-
Direct stimulation
- IMI:
-
Intelligent medical implants
- IRI:
-
Intelligent retinal implant
- LGN:
-
Lateral geniculate nucleus
- LP:
-
Light perception
- MPDA:
-
Microphotodiode array
- NLP:
-
No light perception
- OCT:
-
Optical coherence tomography
- rd1:
-
Retinal degeneration 1
- RP:
-
Retinitis pigmentosa
- RPE65:
-
Retinal pigment epithelium-specific 65 kDa protein
- SSMP:
-
Second Sight Medical Products, Inc.
- V1:
-
Primary visual cortex
- VPU:
-
Visual processing unit
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Horsager, A., Fine, I. (2011). The Perceptual Effects of Chronic Retinal Stimulation. In: Dagnelie, G. (eds) Visual Prosthetics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0754-7_14
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