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In Vivo Left Ventricular Geometry and Boundary Conditions

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Computational Cardiovascular Mechanics

Abstract

The first basic biomechanics modeling step outlined in the introductory chapter is to define the geometric configuration. In Chapters 12 and 14 we demonstrate the application of either simple (i.e., axisymmetric truncated ellipsoid) or complex (i.e., fully 3-D) left ventricular (LV) geometric models or finite element (FE) meshes. This chapter is primarily concerned with an instructive review of the methodology we have used to create both types of FE meshes, which relies on the “parametric” meshing software TrueGrid®. Since TrueGrid is rather expensive, Section 1.6 describes the use of free software executables available from the Pacific Northwest National Laboratory. The second basic biomechanics modeling step (determine mechanical properties) is addressed in the next three chapters. The third and fourth basic biomechanics modeling steps (governing equations and boundary conditions) are discussed briefly at the end of this chapter.

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Acknowledgments

This research was supported by National Institutes of Health grants 5R01 HL077921 (Dr. Guccione) and 5R01 HL063348 (Dr. Ratcliffe), and by CardioPolymers, Inc. (Drs. Guccione and Wenk).

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Authors and Affiliations

  1. Department of Surgery, University of California at San Francisco and San Francisco VA Medical Center, San Francisco, CA, USA

    Jonathan F. Wenk, Choon-Sik Jhun, Zhihong Zhang, Kay Sun, Mark Ratcliffe & Julius M. Guccione

  2. XYZ Scientific Applications Inc., Livermore, CA, USA

    Mike Burger

  3. Biological Monitoring and Modeling, Pacific Northwest National Laboratory, Olympia, WA, USA

    Dan Einstein

Authors
  1. Jonathan F. Wenk
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  2. Choon-Sik Jhun
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  3. Zhihong Zhang
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  4. Kay Sun
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  5. Mike Burger
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  6. Dan Einstein
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  7. Mark Ratcliffe
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  8. Julius M. Guccione
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Corresponding author

Correspondence to Julius M. Guccione .

Editor information

Editors and Affiliations

  1. Veterans Affairs Medical Center, University of California, San Francisco, Clement St. 4150, San Francisco, 94121, U.S.A.

    Julius M. Guccione

  2. Purdue University Indianapolis, Indiana University, Barnhill Drive 635, Indianapolis, 46202, U.S.A.

    Ghassan S. Kassab

  3. Veterans Affairs Medical Center, University of California, San Francisco, Clement St. 4150, San Francisco, 94121, U.S.A.

    Mark B. Ratcliffe

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Wenk, J.F. et al. (2010). In Vivo Left Ventricular Geometry and Boundary Conditions. In: Guccione, J., Kassab, G., Ratcliffe, M. (eds) Computational Cardiovascular Mechanics. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0730-1_1

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  • DOI: https://doi.org/10.1007/978-1-4419-0730-1_1

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  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4419-0729-5

  • Online ISBN: 978-1-4419-0730-1

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