Perspectives On DNA Looping

  • Laura FinziEmail author
Conference paper
Part of the The IMA Volumes in Mathematics and its Applications book series (IMA, volume 150)

DNA looping is a ubiquitous regulatorymechanism which can be involved in DNA transcription, ecombination, repair, etc. Here, I will focus on protein-mediated DNA looping as a mechanism of tran-scriptional regulation. Indeed, such topological change in DNA is known to repress and/or activate many prokaryotic and viral genes [1–4] and is believed to mediate interaction between promoters and enhancers as well as insulate them in eukaryotes [5–9].


Loop Formation Negative Supercoiling Biophysical Journal Magnetic Tweezer Lambda Repressor 
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Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  1. 1.Department of PhysicsEmory UniversityAtlantaUSA

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