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Intracrine Function from Angiotensin to Stem Cells

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The Local Cardiac Renin-Angiotensin Aldosterone System

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Abstract

Intracrine action is increasingly being appreciated as a physiologically relevant signaling mechanism. Growing out of the study of angiotensin biology, intracrine physiology is becoming better understood and general principles of intracrine action have been proposed. Here the field will be briefly reviewed and some predictions of intracrine theory discussed to illustrate these principles of intracrine action. The potential relevance of these ideas to the working of the local renin–angiotensin systems and to diverse other biological processes such as differentiation and neoplasia is discussed.

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Authors and Affiliations

  1. Ochsner Clinic Foundation, 70121, New Orleans, LA, USA

    Richard N. Re & Julia L. Cook (Co-Director Molecular Genetics)

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  1. Richard N. Re
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  2. Julia L. Cook
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Editors and Affiliations

  1. Ochsner Clinic Foundation, Jefferson Highway 1514 , New Orleans, 70121, U.S.A.

    Edward D. Frohlich

  2. Ochsner Clinic Foundation, Jefferson Highway 1514 , New Orleans, 70121, U.S.A.

    Richard N. Re

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Re, R.N., Cook, J.L. (2009). Intracrine Function from Angiotensin to Stem Cells. In: Frohlich, E., Re, R. (eds) The Local Cardiac Renin-Angiotensin Aldosterone System. Springer, Boston, MA. https://doi.org/10.1007/978-1-4419-0528-4_9

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  • DOI: https://doi.org/10.1007/978-1-4419-0528-4_9

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