Potential of Nanobiotechnology in the Management of Glioblastoma Multiforme
Glioblastoma multiforme (GBM) is a challenge in management as no cure has been found for this brain cancer. Among new technologies that are being applied to improve management of GBM, nanobiotechnology plays an important role. This chapter reviews the role of new approaches based on nanobiotechnology for improving diagnosis as well as for developing new drugs. The most important challenge is targeted delivery of therapeutics across the blood–brain barrier to the tumor without damaging the normal brain. Integration of diagnosis with therapeutics will facilitate personalized management of GBM.
KeywordsBlood brain barrier Brain cancer Brain tumors Cancer chemotherapy Gene therapy Glioblastoma multiforme Nanobiotechnology Nanooncology Nanoparticles Neurooncology
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