Vascular Glucose Transport and the Metabolic Syndrome

  • Fatima Martel
  • Elisa Keating


The metabolic syndrome comprises a wide range of physiopathological abnormalities, all involved in systemic changes, occurring in different territories of the body. Glucose transporter changes throughout the body are observed in diverse degrees in the metabolic syndrome. This chapter aims to describe the alterations of glucose transport associated with the metabolic syndrome occurring at the vascular level. We will highlight the mechanisms regulating glucose transport in endothelial and vascular smooth muscle cells derived from peripheral vascular beds and from the blood-brain and blood-retinal barriers. Knowledge on this subject will contribute for understanding the physiopathology of the metabolic syndrome, as well as possible treatments for this condition.


Diabetes Endothelium Glucose transport Metabolic syndrome Vascular smooth muscle 


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Fatima Martel
    • 1
  • Elisa Keating
    • 2
  1. 1.Department of Biochemistry (U38-FCT), Faculty of MedicineUniversity of Porto, Al. Prof. Hernâni MonteiroPortoPortugal
  2. 2.Department of Biochemistry (U38-FCT), Faculty of MedicineUniversity of Porto, Al. Prof. Hernâni MonteiroPortoPortugal

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