The Application of Cell Based Biosensor and Biochip for EnvironmentalMonitoring

  • Junhong Min
  • Cheol-Heon Yea
  • Waleed Ahmed El-Said
  • Jeong-Woo Choi


The cell based biosensor has outstanding advantages in aspect of environmental monitoring, comparing with DNA or protein based biosensor. Various cell based biosensors to detect toxic chemicals have been researched in few decades and applied directly to environmental fields. In this study, some key technologies such as cell immobilization technology, on-chip cell cultivation technology, and cell viability detection technology required to develop cell based biosensors are categorized and briefly discussed. We suggests that cell based biochip can be applied to environmental monitoring by demonstrating that phenol can be successfully measured by two distinct cell based label-free biochips, SPR based cell chip and electric based cell chip, developed using key technologies.


Cell chip Electrochemical detection SPR HepG2 


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Copyright information

© Springer Science+Business Media B.V. 2009

Authors and Affiliations

  • Junhong Min
    • 1
  • Cheol-Heon Yea
    • 2
  • Waleed Ahmed El-Said
    • 3
  • Jeong-Woo Choi
    • 4
  1. 1.College of Bionano technologyKyungwon UniversitySeongnamKorea
  2. 2.Department of Chemical and Bomolecular EngineeringSogang UniversityKorea
  3. 3.Interdisciplenary Program of Integrated BiotechnologySogang UniversityKorea
  4. 4.College of Bionano technologyKyungwon UniversitySeongnamKorea

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