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Lymphomas of the gastrointestinal tract

  • Conference paper
Pathogenesis and Clinical Practice in Gastroenterology

Part of the book series: Falk Symposium ((FASS,volume 160))

  • 625 Accesses

Abstract

The gastrointestinal tract is the most frequently involved extranodal localization, representing 30–40% of extranodal lymphomas and from 4% to 20% of all non-Hodgkin’s lymphoma (NHL) cases1, 2. In Western countries the most common location is the stomach (approximately 50–60%), followed by the small intestines (30%) and the large intestine (around 10%)3. Involvement of the oesophagus is very rare. These proportions can differ geographically, with small intestinal lymphomas being more common in the Middle East. The most common histological subtype in localized gastrointestinal tract presentations is diffuse large B-cell lymphoma which is present in approximately 60% of the gastric and 70% of the intestinal cases. Mucosa-associated lymphoid tissue (MALT) lymphoma represents about 35% of primary gastric lymphoma but less than 10% of the intestinal ones. Follicular lymphomas are very rare in the stomach but have been reported in up to 17% of intestinal cases. The other histological subtypes include T-cell lymphomas, Burkitt’s lymphoma and mantle cell lymphomas (which in the gastrointestinal tract often present as a multiple lymphomatous polyposis) and are much less common and taken together comprise approximately 5% of the cases3, 4. The incidence of gastrointestinal lymphoma may have increased over recent decades5, 6. This is probably due to an actual increase, but more efficient case registration and improved diagnostic tools have also played a role.

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Authors and Affiliations

  1. IOSI-Oncology Institute of Southern Switzerland, Ospedale San Giovanni, 6500, Bellinzona, Switzerland

    E. Zucca

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  1. E. Zucca
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Editor information

Editors and Affiliations

  1. Department of Gastroenterology, Medical Centre Ljubljana, Slovenia

    I. Ferkolj

  2. University of Vienna, Vienna, Austria

    A. Gangl

  3. University of Mainz, Mainz, Germany

    P. R. Galle

  4. University Hospital Rebro, Zagreb, Croatia

    B. Vucelic

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Zucca, E. (2008). Lymphomas of the gastrointestinal tract. In: Ferkolj, I., Gangl, A., Galle, P.R., Vucelic, B. (eds) Pathogenesis and Clinical Practice in Gastroenterology. Falk Symposium, vol 160. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8767-7_12

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  • DOI: https://doi.org/10.1007/978-1-4020-8767-7_12

  • Publisher Name: Springer, Dordrecht

  • Print ISBN: 978-1-4020-8766-0

  • Online ISBN: 978-1-4020-8767-7

  • eBook Packages: MedicineMedicine (R0)

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