Abstract
The development of new techniques to investigate quantitatively the expression of genes in the cell has shed light on a number of systems which display regular oscillations in protein concentration. In order to investigate the physics which controls such systems, one can make use of models based on rate equations. The models present in the literature suggest that important ingredients to describe correctly oscillations in protein expression are a feed–back loop, time delay and saturated binding. In this review we will discuss the physical aspects of the mechanism which is at the basis of the oscillations in gene expression.
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Jensen, M.H., Krishna, S., Sneppen, K., Tiana, G. (2008). Dynamical Genetic Regulation. In: Skjeltorp, A.T., Belushkin, A.V. (eds) Evolution from Cellular to Social Scales. NATO Science for Peace and Security Series B: Physics and Biophysics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8761-5_5
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