Novel Alternative Scaffolds and Their Potential Use for Tumor Targeted Radionuclide Therapy

  • Fredrik Y. Frejd


The class of macromolecules referred to as “Alternative Scaffolds” is reviewed in this chapter. A general introduction to alternative scaffolds is presented, and groups of alternative scaffolds are described according to structural folds. The properties of these biomolecules as molecular recognition tools are presented, scaffolds of special interest for targeted radionuclide therapy are highlighted and tumor targeting data is discussed.


Tumor Target Tumor Uptake Ankyrin Repeat Affibody Molecule Target Radionuclide Therapy 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science + Business Media B.V 2008

Authors and Affiliations

  • Fredrik Y. Frejd
    • 1
    • 2
  1. 1.Unit of Biomedical Radiation Sciences, Department of Oncology, Radiology and Clinical Immunology, Rudbeck LaboratoryUppsala UniversityUppsalaSweden
  2. 2.Affibody ABBrommaSweden

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