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Lipolysaccharide-Induced Monocyte Retention in the Lung

Role of Monocyte Stiffness, Actin Assembly, and CD18-Dependent Adherence

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Progress in Scale Modeling

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References

  1. Hunt, T. K., D. R. Knighton, K. K. Thakral, W. H. Goodson, and W. S. Andrews. 1984. Studies on inflammation and wound healing: angiogenesis and collagen synthesis stimulated in vivo by resident and activated wound macrophages. Surgery 96:48.

    Google Scholar 

  2. Khalil, N., O. Bereznay, M. Sporn, and A. H. Greenberg. 1989. Macrophage production of transforming growth factor β and fibroblast collagen synthesis in chronic pulmonary inflammation. J. Exp. Med. 170:727.

    Article  Google Scholar 

  3. Khalil, N., R. O’Connor, H. Unruh, P. Warren, A. Kemp, and A. Greenberg. 1991. Enhanced expression and imunohistochemical distribution of transforming growth factor-β in idiopathic pulmonary fibrosis. Chest 99:65.

    Article  Google Scholar 

  4. Martin, B. M., M. A. Gimbrone, F. R. Unanue, and R. S. Cotran. 1981. Stimulation of nonlymphoid mesenchymal cell proliferation by a macrophage-derived growth factor. J. Immunol. 126:1510.

    Google Scholar 

  5. Piquet, P. F., M. A. Collart, G. E. Grau, A. P. Sappino, and P. Vassalli 1990. Requirement of tumor necrosis factor for development of silica-induced pulmonary fibrosis. Nature 344:245.

    Article  Google Scholar 

  6. Rappolee, D. A., D. Mark, M. J. Bander, and Z. Werb. 1988. Wound macrophages express TGF-β and other growth factors in vivo: analysis by mRNA phenotyping. Science 241:708.

    Article  Google Scholar 

  7. Engelhardt, R., A. Mackensen, C. Galanos, and R. Andreesen 1990. Biological response to intravenously administered endotoxin in patients with advanced cancer. J. Biol. Response Modif. 9:480.

    Google Scholar 

  8. Mackensen, A., C. Galanos, U. Wehr, and R. Engelhardt 1992. Endotoxin tolerance: regulation of cytokine production and cellular changes in response to endotoxin application in cancer patients, Eur. Cytokine Netw. 3:571.

    Google Scholar 

  9. Engelhardt, R., A. Mackensen, and C. Galanos. 1991. Phase I trial of intravenously administered endotoxin (Salmonella abortus equi) in cancer patients. Cancer Res. 15:2524.

    Google Scholar 

  10. Haslett, C., G. S. Worthen, P. C. Giclas, D. C. Morrison, J. E. Henson, and P. M. Henson 1987. The pulmonary vascular sequestration of neutrophils in endotoxemia is initiated by an effect of endotoxin on the neutrophil in the rabbit. Am. Rev. Respir. Dis. 130:9.

    Google Scholar 

  11. Kane, M. A., J. E. May, and M. M. Frank. 1973. Interactions of the classical and alternate complement pathway with endotoxin lipopolysaccharide effect on platelets and blood coagulation. J. Clin. Invest. 52:370.

    Article  Google Scholar 

  12. Meyrick, B., and K. L. Brigham. 1986. Repeated Escherichia coli endotoxin-induced pulmonary intlammation causes chronic pulmonary hypertension in sheep: structural and functional changes. Lab. Invest. 55:164.

    Google Scholar 

  13. Meyrick, B., and K. L. Brigham. 1983. Acute effects of Escherichia coli endotoxin on the pulmonary microcirculation of anesthetized sheep, structure: function relationships, Lab, Invest, 48:458.

    Google Scholar 

  14. Erzurum, S. C., G. P. Downey, D. E. Dohorty, B. Schwab III, E. I., Hilson, and G. S. Worthen. 1992. Mechanisms of lipopolysaccharideinduced neutrophil retention; relative contributions of adhesive and cellular mechanical properties. J. Immunol. 149:154.

    Google Scholar 

  15. Worthen, G. S., C. Haslett, A. J. Rees, R. S. Gumbay, J. E. Henson and P. M. Henson. 1987. Neutrophil mediated pulmonary vascular injury: synergistic effect of trace amounts of lipopolysaccharide and neutrophil stimuli on vascular permeability and neutrophil sequestration in the lung. Am. Rev. Respir. Dis. 136:19.

    Google Scholar 

  16. Glazier, J. B., J. M. Hughes, J. E. Maloney, and J. B. West. 1969. Measurements of capillary dimensions and blood volume in rapidly frozen lungs. J. Appl. Physiol. 26:65.

    Google Scholar 

  17. Gumheroth, W. G., D. L. Lachrer, and I. Kawabori, 1982. Pulmonary microcirculation: tubules rather than sheet and post. J. Appl. Physiol. 53:510.

    Google Scholar 

  18. Duersehuk, C. M., N. Beyers, H. O. Cosson, B. Wiggs, and J. C. Hogg. 1993. Comparison of neutrophil and capillary diameters and their relation to neutrophil sequestration in the lung. J. Appl. Physiol. 74:3040.

    Google Scholar 

  19. Downey, G. P., D. E. Doherry, B. Schwab III, E. L. Elson. P. M. Henson, and G. S. Worthen. 1990. Retention of leukocyles in capillaries: role of cell size and deformability. J. Appl. Physiol. 69: 1767.

    Google Scholar 

  20. Schmidt-Schonbein, G. W., Y. Y. Shih, and S. Chien. 1985. Morphometry of human leukocytes, Blood 56:866.

    Google Scholar 

  21. Worthen, G. S., B. Schwab, E. L. Elson, and G. P. Downey. 1989. Mechanics of stimulated neutrophils: cell stiffoning retention in capillaries. Science 245:183.

    Article  Google Scholar 

  22. Downey, G. P., E. L. Elson, B. Schwab III. S. C. Erzurum, S. K. Young, and G. S. Worthen. 1991. Biophysical properties and microfilament assembly in neutrophils: modulation by cyclic AMP. J. Cell Biol. 114:1179.

    Article  Google Scholar 

  23. Larrick, J. W., D. Graham, K. Toy, L. S. Lin, G. Senyk, and B. M. Fendly. 1987. Recombinant tumor necrosis factor causes activation of human granulocytes. Blood 69:640.

    Google Scholar 

  24. Smith, C. M., D. P. Tukey, D. Mundshenk, W. Krivit, J. G. White, J. E. Repine, and J. R. Hoidal. 1982. Filtration deformability at rabbit pulmonary macrophage, J. Lab. Clin. Med. 99:568.

    Google Scholar 

  25. Howard. T. H., and W. H. Meyer. 1984. Chemotactic peptide modulation of actin assembly and locomotion in neutrophils. J. Cell Biol. 98:1265.

    Article  Google Scholar 

  26. Downey, G. P., and G. S. Worthett. 1988. Neutrophil retention in model capillaries: deformability, geometry, and hydrodynamic forces. J. Appl. Physiol. 65:1861.

    Google Scholar 

  27. Osborn, L. 1990. Leukocyte adhesion to endothelium in inflammation. Cell 62:3.

    Article  Google Scholar 

  28. Mentzer, S. J., M. A. V. Crimmins, S. J. Burakoff, and D. V. Faller. 1987. Alpha and beta subunits of the LFA-l membrane molecule are involved in human monocyte-endothelial cell adhesion. J. Cell. Phys. 130:410.

    Article  Google Scholar 

  29. Wallis, W. J., P. G. Beatry. H. D. Ochs, and J. M. Harlan. 1985. Human monocyte adherence to cultured vascular endothelium; monoclonal antibody-defined mechanisms. J. Immunol, 135:2323.

    Google Scholar 

  30. Doherty, D. E., L. Zagarella, P. M. Henson, and G. S. Worthen. 1989. Lipopolysaceharide stimulates monocyte adherence by effects on both the monocyte and the endothelial cell. J. Immunol. 143:3673.

    Google Scholar 

  31. Bevilacqua, M. P., J. S. Pober, M. E. Wheeler, R. S. Cotran, and M. A. Gimbrone, Jr. 1985. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J. Clin. Invest. 76:2003.

    Article  Google Scholar 

  32. Bevilacqua, M. P., J. S. Pober, M. E. Wheeler, R. S. Cotran, and M. A. Gimbrone, Jr. 1985. Interleukin-J. activation of vascular endothelium: effects on procoagulant activity and leukocyte adhesion. Am. J. Pathol. 121:393.

    Google Scholar 

  33. Pohlman, T. H., K. A. Stanness, B. G. Beatty, H. D. Ochs, and J. M. Harlan. 1986. An endothelial cell surface factor(s) induced in vitro by lipopolysaccharide. IL-1, and tumor necrosis factor increases neutrophil adherence by CDW18-dependent mechanism. J. Immunol, 130:4545.

    Google Scholar 

  34. Doherty, D. E., C. Haslett, M. G. Tonnesen, and P. M. Henson, 1987. Human monocyte adherence: a primary effect of chemotactic factors on the monocyte to stimulate adherence to human endothelium, J. Immunol. 138:1762.

    Google Scholar 

  35. Doherty, D. E., G. Downey, G. S. Worthen, C. Haslett, and P. M. Henson. 1988. Monocyte retention and migration in pulmonary inflammation; requirement for neutrophils. Lab. Invest. 59:200.

    Google Scholar 

  36. Doherty, D. E., P. M. Henson, and R. A. F. Clark. 1990. Fibronectin fragments containing the RGDS cell-binding domain mediate monocyte migration into the rabbit lung: a potential mechanism for C5 fragment-induced monocyte lung accumulation. J. Clin. Invest. 86:1065.

    Article  Google Scholar 

  37. Clark. R. A. F., N. E. Wickner, D. E. Doherty, and D. A. Norris. 1988. Cryptic chemotactic activity of fibronectin for human monocytes resides in the 120 kDa fibroblastic cell-binding fragment. J. Biol. Chem. 263:12115.

    Google Scholar 

  38. Shaw, R. J., D. E. Doherty, A. G. Ritter, S. H. Benedict, and R. A. F. Clark. 1990. Adherence-dependent increase in human monocyte PDGF(B) mRNA is associated with increases in c-fos, c-jun, and EGR2 mRNA, J. Cell Biol. 111:2139.

    Article  Google Scholar 

  39. Doherty, D. E., N. Hirose, and R. M. Cherniack. 1992. Monocyte lung accumulation during the acute phase of bleomycin-induced lung inflammation in the rabbit noninvasive assessment by external scintigraphy. Lab Invest. 66:231.

    Google Scholar 

  40. Ohgami, M., C. M. Doerschuk, R. P. Gie, D. English, and J. C. Hogg. 1991. Monocyte kinetics in rabbits. J. Appl. Physiol. 70:152.

    Google Scholar 

  41. Doerschuk, C. M., R. K. Winn, H. O. Coxson, and J. M. Harlan, 1990. CD18-dependent and -independent mechanisms of neutrophil emigration in the pulmonary and systemic microcirculation of rabbits. J. Immunol. 144:2327.

    Google Scholar 

  42. Arfors, K.-E., C. Lundberg, L. Lindbom, K. Lundberg, P. G. Beally, and J. M. Harlan. 1987. A monoclonal antibody to the membrane glycoprotein complex CD18 inhibits polymorphonuclear leukocyte accumulation and plasma leakage in vivo. Blood 69:338.

    Google Scholar 

  43. Vedder, N. B., R. K. Winn, C. L. Rice, E. Y. Chi, K. E. Arfors, and J. M. Harlan. 1988. A monoclonal antibody to the adherence-promoting jeukocyte glycoprotein. CD18, reduces organ injury and improves survival from hemorrhagic shock and resuscitation in rabbits. J. Clin. Invest. 81:939.

    Article  Google Scholar 

  44. Muirhead, K. A., L. C. Schmitt, and A. R. Muirhead. 1983. Determination of linear fluorescence intensities from flow cytometric data accumulated with logarithmic amplifiers. Cytometry 3:251.

    Article  Google Scholar 

  45. Petersen, N. O., W. B. McConnaughey, and E. L. Elson. 1982. Dependence of locally measured cellular deformability on position on the cell, temperature, and cytochalasin B. Proc. Natl. Acad. Sci. USA 79:5327.

    Article  Google Scholar 

  46. Pasternak, C., and E. L. Elson. 1985. Lymphocyre mechanical response triggered by cross-linking surface receptors. J. Cell Biol. 108:860.

    Article  Google Scholar 

  47. Zar. J. H. 1984. Biostatistical Analysis, 2nd Ed. Prentice-Hall. Englewood Cliffs, NJ.

    Google Scholar 

  48. Litrell, R. C., R. J. Freund, and P. C. Spector. 1991. SAS System for Linear Models. 3rd Ed. SAS Institute, Cary. NC.

    Google Scholar 

  49. Pasternack, M. S., and H. N. Eisen. 1985. A novel serine esierase expressed by cytotoxic T-lymphocytes. Nuture 314:743.

    Article  Google Scholar 

  50. Erzurum, S. C., C. Kus, C. Bohse, E. L. Elson, and G. S. Worthen. 1991. Mechanical properties of H1.60 cells: Role of stimulation and differentiation in retention in capillary-sized pores. Am. J. Respir. Cell Mol. Biol. 5:230.

    Google Scholar 

  51. Doerschuk, C. M., G. P. Downey, D. E. Doherty, D. English, R. P, Gie, M. Ohgami, G. S. Worthen, P. M. Henson, and J. C. Hogg. 1990. Leukocyte and platelet margination within the microvasculature of rabbit lungs. J. Appl. Physiol, 68:1956.

    Google Scholar 

  52. Doerschuk, C. M., M. F. Allard, B. A. Martin, A. MacKenzie, A. P. Autor, and J. C. Hogg. 1987. Marginated pool of neutrophils in rabbit lungs. J. Appl. Physiol. 63:1806.

    Google Scholar 

  53. Pasternak, C., J. A. Spudich, and E. L. Elson. 1989. Capping of surface receptors and concornitant cortical tension are generated by conventional myosin. Nature 341:549.

    Article  Google Scholar 

  54. Rosen, H., and S. Gordon. 1987. Monoclonal antibody to the murine type 3 complement receptor inhibits adhesion of myelomonocytic cells in vitro and inflammatory cell recruitment in vivo. J. Exp. Med. 166:1685.

    Article  Google Scholar 

  55. Hakkert, B. C., T. W. Kuijpers, J. F. M. Leeuwenberg. J. A. van Mourik, and D. Roos. 1991. Neutrophil and monocyte adherence to and migration across monolayers of cylokine-activated endothelial cells: the contribution of CD18. ELAM-1, and VLA-4. Blood 78:2721.

    Google Scholar 

  56. Van Furth, R., and W. Sluiter. 1986. Distribution of blood monocytes between a marginating and a circulating pool. J. Exp. Med. 163:474.

    Article  Google Scholar 

  57. Winn. R. K., and J. M. Harlan. 1993. CD18-independent neutrophil and mononuclear leukocyte emigration into the peritoneum of rabbits. J. Clin. Invest. 92:1168.

    Article  Google Scholar 

  58. Doherty, D. E., P. S. Tobias, R. J. Ulevitch, and G. S. Worthen. 1992. The role of LPS-binding protein and CD14 in LPS-induced monocyte adherence. Am. Rev. Respir. Dis. 145:A660.

    Google Scholar 

  59. Doherty, D. E., J. Leadbeater, and L. Zagarella, 1993. LPS induced monocyte retention in model capillaries: role of plasma and the LPS receptor CD14. Am. Rev. Respir. Dis. 147:A245.

    Google Scholar 

  60. Schumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevich. 1990. Structure and function of lipopolysaccharide binding protein. Science 249:1429.

    Article  Google Scholar 

  61. Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysacchraride (LPS) and LPS-binding protein. Science 249:1431.

    Article  Google Scholar 

  62. Kirkland, T. N., F. Finley, D. Leturcq, A. Moriarty, J.-D. Lee, R. J. Ulevitch, and P. S. Tobias. 1993. Analysis of lipopolysaccharide binding by CD14, J. Biol. Chem. 268:24818.

    Google Scholar 

  63. Worthen, G. S., N. Avdi, S. Vukajlovich, and P. S. Tobias. 1992. Neutrophil adherence induced by lipopolysaccharide in vitro: role of plasma component interaction with lipopolysaccharide. J. Clin. Invest. 90:2526.

    Article  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of Medicine, National Jewish Center for Immunology and Respiratory Medicine, 1400 Jackson St., Denver, CO 80206

    Dennis E. Doherty (Dr.), Gregory P. Downey & G. Scott Worthen

  2. University of Colorado School of Medicine, and the Denver Veterans Administration Medical Center, Denver, CO 80206

    Dennis E. Doherty (Dr.) & G. Scott Worthen

  3. Denver Veterans Administration Medical Center, Denver, CO 80206

    Dennis E. Doherty (Dr.)

  4. Department of Biochemistry and Molecular Biophysics, Washington University, St. Louis, MO 63110

    Bill Schwab III & Elliot Elson

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  1. Dennis E. Doherty
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  2. Gregory P. Downey
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  3. Bill Schwab III
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  4. Elliot Elson
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  5. G. Scott Worthen
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Editor information

Editors and Affiliations

  1. Dept. Mechanical Engineering and Institute of Research for Technology Development, University of Kentucky, 151 RGAN Bldg., Lexington, KY 40506-0503, USA

    Kozo Saito

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Doherty, D.E., Downey, G.P., Schwab, B., Elson, E., Worthen, G.S. (2008). Lipolysaccharide-Induced Monocyte Retention in the Lung. In: Saito, K. (eds) Progress in Scale Modeling. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8682-3_37

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