Homeotic miRNAs: From Development to Pathologies

  • Maya Ameyar-Zazoua
  • Irina Naguibneva
  • Linda Pritchard
  • Annick Harel-Bellan

Abstract Hox genes are key elements for anterio-posterior morphogenesis. Hox genes are tightly regulated at the transcriptional level. This level of regulation, however, is by far not unique, and non-coding RNAs, and in particular micro-RNAs, provide an important supplementary level of regulation. This review recapitulates what is known about Hox-related microRNAs, describes a technique that can be used to address miRNA function and attempts to speculate on the function of regulation by miRNAs and how it may impact on medicine.


miRNA Hox LNA 


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Copyright information

© Springer Science + Business Media B.V 2008

Authors and Affiliations

  • Maya Ameyar-Zazoua
    • 1
  • Irina Naguibneva
    • 1
  • Linda Pritchard
    • 1
  • Annick Harel-Bellan
    • 1
  1. 1.Centre National de la Recherche Scientifique (CNRS) FRE 2944, Institut André Lwoff, Villejuif F-94801France; Université Paris-SudVillejuifFrance

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