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Hybrid Siloxane-Polyaminoamides for the Absorption of Heparin from Blood

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Abstract

Heparin is an anticoagulant which is widely used during blood-dialysis. To now, there is not a commercial device able to “filter” heparin from blood after or during the medical treatment. Heparin can give, on life-long treatments, several health problems. We prepared siloxane-modified hybrid poly(aminoamides) which can be obtained from water solution. They shown good heparin absorption properties.

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References

  1. W. Li, D. J. D. Johnson, C. T. Esmon, J. A. Huntington, Nat. Struct. Mol. Biol., 11, 857 (2004); I. Bjork, U. Lindahl, Mol. Cell. Biochem., 48, 161 (1982).

    Google Scholar 

  2. L. K. Von Segesser, T. Mihailevic, M. Toenz, B. Leskosek, A. Von Felten, M. Turina, Asaio J., 40, M565 (1994); D. Jegger, H. T. Tevaerai, J. Horisberger, X.M. Mueller, I. Seigneuil, N. Pierrel, Y. Boone, L. K. von Segesser, Perfusion, 15, 453 (2000); H. T. Tevaearai, D. Jegger, X.M. Mueller, J. Horisberger, L. K. von Segesser, Thorac. Cardiov. Surg., 46, 303 (1998).

    Google Scholar 

  3. P. Ferruti, E. Ranucci, G. Di Silvestro, C. Yuan, N. Caronzolo, R. Donetti, M. Marchisio, La Chimica e L’Industria, 739 (1999); P. Ferruti, M. Marchisio, R. Duncan, Macromol. Rapid Commun., 23, 332 (2002).

    Google Scholar 

  4. D. Cauzzi, G. Predieri, A. Stercoli, L. Balzano Patent (2004). “Composti xerogel polimerici reticolati inorganico-organici di poliammidoammine silossanizzate, loro metodo di prepar-azione e loro utilizzo come materiali eparino-assorbenti.” MI2004A000503. C.O.M.E.F. S.r.l. Carpi (MO).

    Google Scholar 

  5. P. K. Smith, A. K. Mallia, G. T. Hermanson, Anal. Biochem., 10, 466 (1980); M. S. Ahola et al., Biomaterials, 22, 2163 (2001).

    Google Scholar 

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Correspondence to Daniele Cauzzi .

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© 2008 Springer Science + Business Media B.V

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Cauzzi, D., Stercoli, A., Predieri, G. (2008). Hybrid Siloxane-Polyaminoamides for the Absorption of Heparin from Blood. In: Innocenzi, P., Zub, Y.L., Kessler, V.G. (eds) Sol-Gel Methods for Materials Processing. NATO Science for Peace and Security Series C: Environmental Security. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-8514-7_17

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