EEG Theta Regulates Eye Saccade Generation During Human Object-place Memory Encoding

  • Naoyuki Sato
  • Yoko Yamaguchi
Conference paper


In this paper, we proposed a computational theory of human memory formation in the hippocampus and determined if electroencephalography (EEG) theta power is associated with eye saccades during object-place memory encoding. EEG theta power and saccade rate is significantly correlated with subsequent recall performance. This result suggests that information acquisition for object-place memory is processed by the theta rhythm network for memory system, attentional regulation and saccades.


Theta Rhythm Theta Power Ocular Artifact Theta Range Theta Phase 
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  1. 1.
    O’Keefe, J., Recce, M.L.: Phase relationship between hippocampal place units and the EEG theta rhythm. Hippocampus 3 (1993) 317–330.PubMedCrossRefGoogle Scholar
  2. 2.
    Skaggs, W.E., McNaughton, B.L., Wilson, M.A., Barnes, C.A.: Theta phase precession in hippocampal neuronal populations and the compression of temporal sequences. Hippocampus 6 (1996) 149–172.PubMedCrossRefGoogle Scholar
  3. 3.
    Bi, G.Q., Poo, M.M.: Synaptic modifications in cultured hippocampal neurons: dependence on spike timing, synaptic strength, and postsynaptic cell type. J. Neurosci. 18 (1998) 10464–10472.PubMedGoogle Scholar
  4. 4.
    Yamaguchi, Y.: A theory of hippocampal memory based on theta phase precession. Biol. Cybern. 89 (2003) 1–9.PubMedGoogle Scholar
  5. 5.
    Yamaguchi, Y., Aota, Y., Sato, N., Wagatsuma, H., Wu, Z.: Synchronization of neural oscillations as a possible mechanism underlying episodic memory: a study of theta rhythm in the hippocampus. J. Integ. Neurosci. 3 (2004) 143–157.CrossRefGoogle Scholar
  6. 6.
    Smith, M.L., Milner, B.: The role of the right hippocampus in the recall of spatial location. Neuropsychologia 19 (1981) 781–793.PubMedCrossRefGoogle Scholar
  7. 7.
    Stepankova, K., Fenton, A.A., Pastalkova, E., Kalina, M., Bohbot, V.D.: Object-location impairment in patient with thermal lesions to the right or left hippocampus. Neuropsychologia 42 (2004) 1017–1028.PubMedCrossRefGoogle Scholar
  8. 8.
    Sato, N., Yamaguchi, Y.: On-line formation of a hierarchical cognitive map for object-place association by theta phase coding. Hippocampus 15 (2005) 963–978.PubMedCrossRefGoogle Scholar
  9. 9.
    Sato, N., Yamaguchi, Y.: Theta synchronization networks emerge during human object-place memory encoding. NeuroReport 18 (2007) 419–424.PubMedCrossRefGoogle Scholar
  10. 10.
    Sato, N., Yamaguchi, Y.: An evidence of a hierarchical representation of object-place memory based on theta phase coding: a computational model-human experiment combined analysis, Program No. 366.25, Society for Neuroscience Abstracts, (2006).Google Scholar
  11. 11.
    Croft, R.J., Barry, R.J.: Removal of ocular artifact from EEG: a review. Neurophysiol. Clin. 30 (2000) 5–19.PubMedCrossRefGoogle Scholar
  12. 12.
    Ekstrom, A.D., Caplan, J.B., Ho, E., Shattuck, K., Fried, I., Kahana, M.J.: Human hippocampal theta activity during virtual navigation. Hippocampus. 15 (2005) 881–889.PubMedCrossRefGoogle Scholar
  13. 13.
    Ulanovsky, N., Moss, C.F.: Hippocampal cellular and network activity in freely moving echolocating bats. Nat. Neurosci. 10 (2007) 224–233.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Naoyuki Sato
    • 1
  • Yoko Yamaguchi
  1. 1.Laboratory for Dynamics of Emergent IntelligenceRIKEN Brain Science InstituteSaitama 351-0198

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