Corticopetal Acetylcholine: A Role in Attentional State Transitions and the Genesis of Quasi-Attractors During Perception

  • Hiroshi Fujii
  • Kazuyuki Aihara
  • Ichiro Tsuda
Conference paper

Abstract

The Role(s) of corticopetal acetylcholine (ACh) in perception and conscious flow is largely unknown. The attention hypothesis may well be established experimentally. The aim of this talk is to give a small review, and then try to extend further the arguments, on the role of corticopetal ACh in perception from a dynamical systems standpoint, to search for its possible role in perceptual binding, and in the transient genesis of quasi-attractors through the mechanism of changing synchrony.

Keywords

Corticopetal acetylcholine nucleus basalis of Meinert complex hallucinations perceptual binding attentions binding through synchrony quasi-attractors muscarinic receptor cortical state transitions 

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Behrendt, R.-P., Young, C.: Hallucinations in schizophrenia, sensory impairment, and brain disease: A unifying model. Behav. Brain Sci. 27 (2004) 771–787.PubMedGoogle Scholar
  2. 2.
    Sarter, M., Gehring, W.J., Kozak, R.: More attention should be paid: The neurobiology of attentional effort. Brain Res. Rev. 51 (2006) 145–160.PubMedCrossRefGoogle Scholar
  3. 3.
    Perry, E.K., Perry, R.H.: Acetylcholine and hallucinations: disease-related compared to drug-induced alterations in human consciousness. Brain Cognit. 28 (1995) 240–258.CrossRefGoogle Scholar
  4. 4.
    Fries, P., Reynolds, J.H., Rorie, A.E., Desimone, R.: Modulation of oscillatory neuronal synchronization by selective visual attention. Science 291 (2001) 1560–1563.PubMedCrossRefGoogle Scholar
  5. 5.
    Buschman, T.J., Miller, E.K.: Top–down versus bottom–up control of attention in the prefrontal and posterior parietal cortices. Science 315 (2007) 1860–1862.PubMedCrossRefGoogle Scholar
  6. 6.
    Kay, L.M., Lancaster, L.R., Freeman, W.J.: Reafference and attractors in the olfactory system during odor recognition. Int. J. Neural Systems 4 (1996) 489–495.CrossRefGoogle Scholar
  7. 7.
    Golmayo, L., Nunez, A., Zaborsky, L.: Electrophysiological evidence for the existence of a posterior cortical-prefrontal-basal forebrain circuitry in modulating sensory responses in visual and somatyosensory rat cortical areas. Neuroscience 119 (2003) 597–609.PubMedCrossRefGoogle Scholar
  8. 8.
    Treisman, A. M., Gelade, G.: A feature-integration theory of attention. Cognit. Psychol. 12 (1980) 97–136.Google Scholar
  9. 9.
    Kenet, T., Bibitchkov, D., Tsodyks, M., Grinvald, A., Arieli, A.: Nerve cell activity when eyes are shut reveals internal views of the world. Nature 425 (2003) 954–956.PubMedCrossRefGoogle Scholar
  10. 10.
    Varela, F., Lachaux, J.-P., Rodriguez, E., Martinerie, J.: The Brainweb: phase synchronization and large-scale integration. Nature Rev. Neurosci. 2 (2001) 229–239.CrossRefGoogle Scholar
  11. 11.
    Hasselmo, M.E., McGaughy, J.: High acetylcholine sets circuit dynamics for attention and encoding; Low acetylcholine sets dynamics for consolidation. Prog. Brain Res. 145 (2004) 207–231.PubMedCrossRefGoogle Scholar
  12. 12.
    Gulledge, A.T., Susanna, S.B., Kawaguchi, Y., Stuart, G.J.: Heterogeneity of phasic signaling in neocortical neurons. J. Neurophysiol. 97 (2007) 2215–2229.PubMedCrossRefGoogle Scholar
  13. 13.
    Niebur, E., Hsiao, S.S., Johnson, K.O.: Synchrony: a neuronal mechanism for attentional selection?. Curr. Opin. Neurobiol. 12 (2002) 190–194.PubMedCrossRefGoogle Scholar

Copyright information

© Springer-Verlag Berlin Heidelberg 2008

Authors and Affiliations

  • Hiroshi Fujii
    • 1
  • Kazuyuki Aihara
  • Ichiro Tsuda
  1. 1.Department of Intelligent Systems Kohyama Center for NeuroscienceKyoto Sangyo UniversityKyoto 603-8555Japan

Personalised recommendations