Global Oscillations of CA3 Neural Fields
The conditions which cause in the hippocampal CA3 field global oscillatory activities behaviorally important for their links to learning and memory, such as theta and gamma rhythms, have been analyzed with great details. To this aim, the theoretical framework devised years ago by the present author for the study of activities of large neural fields, has been enhanced in such a way to take into account basic biological features. By using that methodology, a two-dimensional model of the entire CA3 field has been described and its activity, originated by the several external inputs impinging on it, has been computer simulated. As a consequence of these investigations, a hypothesis has been elaborated on the relationship between global oscillatory activities of CA3 and engram formation.
KeywordsDentate Gyrus Pyramidal Neuron Entorhinal Cortex Medial Septum Neural Field
Unable to display preview. Download preview PDF.
- 1.Milner B.: Disorders of learning and memory after temporal lobe lesions in man. Clinical Neurosurg. 19 (1972) 421–446Google Scholar
- 3.Squire L. R., Shimamura A.P. and Amaral D. G.: Memory and the hippocampus. In Neural Models of Plasticity (eds Byrne J. H. and Berry W. O.) Academic Press, San Diego (1989) 208–239Google Scholar
- 5.Ventriglia F.: Towards a kinetic theory of cortical-like neural fields. In Neural Modeling and Neural Networks (ed Ventriglia F.) Pergamon Press, Oxford-New York (1994) 217–249Google Scholar
- 6.Ventriglia F.: Kinetic approach to neural systems. I. Bull. Math. Biol. 36 (1974) 534–544Google Scholar
- 8.Paxinos G. and Watson C.: The rat brain in stereotaxic coordinates. Academic Press, San Diego (1986)Google Scholar
- 10.Vertes R. P.: Brainstem modulations of hippocampus: anatomy, physiology, and significance. In The Hippocampus (eds Isaacson R. L. and Pribram K. L.), Vol. 4 Plenum Press, New York (1986) 41–75Google Scholar