The cancer gene theory has provided an intellectual framework for understanding how cancers arise and how they grow. That mutated genes provide selective advantages at various stages of tumor growth explains how tumorigenesis is related to both our environment and our inborn genetic makeup. These insights rank among the great accomplishments of modern science. Most importantly, the cancer gene theory guides the most promising efforts to prevent, diagnose, treat and cure cancer.
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(2008). Cancer Genetics in the Clinic. In: Principles of Cancer Genetics. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6784-6_7
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DOI: https://doi.org/10.1007/978-1-4020-6784-6_7
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