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Mitochondria: Structure, Function and Relationship with Carcinogenesis

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Oxidation: The Cornerstone of Carcinogenesis

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References

  1. Papa S. The F0F1-H+ synthase of mitochondria. In: Tager J.M., Azzi A., Papa S., Guerrieri F. eds., Organelles in eukaryotic cell: molecular structure and interactions. New York, London, Plunum publ. Co 9–26 (1989)

    Google Scholar 

  2. Inomoto T., Tanaka A., Moris S., Jin M.B., Sato B., Yanabu N., Tokuka A., Kitai T., Ozawa K., Yamaoka Y. Biochim. Biophys. Acta 1188:311–317 (1994)

    Article  PubMed  Google Scholar 

  3. Guerrieri F., Muolo L., Cocco T., Capozza G., Turturro N., Cantatore P., Papa S. Biochim. Biophys. Acta 1272:95–100 (1995)

    PubMed  Google Scholar 

  4. Massari S., Azzone G.F. Biochim. Biophys. Acta 1241:23–29 (1972)

    Google Scholar 

  5. Halestrap A.P., Kerr P.M., Javadov S., Woodfiels K.Y. Biochim. Biophys. Acta 1366:79–94 (1998)

    Article  PubMed  CAS  Google Scholar 

  6. Vance J.E. J. Biol. Chem. 265:7248–7256 (1990)

    PubMed  CAS  Google Scholar 

  7. Ardail D., Lerme F., Luisot P. J. Biol. Chem. 266:7978–7981 (1991)

    PubMed  CAS  Google Scholar 

  8. Moynagh P.N. Essays Biochem. 30:1–14 (1995)

    PubMed  CAS  Google Scholar 

  9. Crompton M. Biochem. J. 34:233–249 (1999)

    Article  Google Scholar 

  10. Crompton M., Heid I. Eur. J. Biochem 91:599–608 (1987)

    Article  Google Scholar 

  11. Crompton M., Capano M., Carafoli E. Eur. J. Biochem. 69:453–462 (1976)

    Article  CAS  Google Scholar 

  12. Crompton M., Kunzi M., Carafoli E. Eur. J. Biochem. 79:549–558 (1977)

    Article  PubMed  CAS  Google Scholar 

  13. Crompton M. In: Calcium and the Heart (Langer G.A. ed.), Raven Press, New York 167–198 (1990)

    Google Scholar 

  14. Crompton M. In: Intracellular Calcium regulation (Bronner F. ed.), Wiley-Liss, New York 181–210 (1990)

    Google Scholar 

  15. Mitchell P. Biol. Rev. 41:445–501 (1966)

    Article  PubMed  CAS  Google Scholar 

  16. Zoratti M., Saylor A.K., Tesfai S.A., Herman B., Lemasters J.J. Biochim. Biophys. Acta 1241:139–176 (1995)

    PubMed  Google Scholar 

  17. Crompton M., Costi A., Hayat L. Biochem. J. 245:915–918 (1987)

    PubMed  CAS  Google Scholar 

  18. Petronilli V., Nicolli A., Constantini P., Colonna R., Bernardi P. Biochim. Biophys. Acta 1187:255–259 (1994)

    Article  PubMed  CAS  Google Scholar 

  19. Broekmeier K.M., Dempsey M.E., Pfeifer D.R. J. Biol. Chem. 264:7826–7830 (1989)

    Google Scholar 

  20. Gunter T.E., Gunter K.K., Shen S.S., Gavin C.E. Am. J. Physiol. 267 (Cell Physiol 36):C313–C339 (1994)

    PubMed  CAS  Google Scholar 

  21. Gunter T.E., Pfeifer D.R., Am. J. Physiol. 258 (Cell Physiol. 27):C755–C786 (1990)

    PubMed  CAS  Google Scholar 

  22. Zoratti M., Szabo I. Biochim. Biophys. Acta 1241:139–176 (1995).

    PubMed  Google Scholar 

  23. Halestrap A.P., Woodfield K.Y., Connern C.P. J. Biol. Chem. 272:3346–3354 (1997)

    Article  PubMed  CAS  Google Scholar 

  24. Novgorodov S.E., Gudz T.I., Milgron Y.M., Brierley G.P. J. Biol. Chem. 267:16274–16282 (1992)

    PubMed  CAS  Google Scholar 

  25. Duchen M., McGuinness O.M., Brown L., Cormpton M. Cardiovasc. Res. 17:1790–1794 (1993)

    Google Scholar 

  26. Petit P.Y., Susin S., Zamzami N., Mignotte B., Kroemer G. FEBS Lett. 396:7–13 (1996)

    Article  PubMed  CAS  Google Scholar 

  27. Kroemer G., Petit P., Zamzami N., Vayssiere J.L., Mignotte B. FASEB J. 9:1277–1287 (1995)

    PubMed  CAS  Google Scholar 

  28. Cohen G.M., Sun X.M., et al. Biochem. J. 286:331–334 (1992)

    PubMed  CAS  Google Scholar 

  29. Kluck R.M., Bossy-Wetzel E., Green D.R., Newmeyer D.D. Science 275:1132–1136 (1997)

    Article  PubMed  CAS  Google Scholar 

  30. Liu X., Kim C.N., Yang J., Jernnierson R., Wang X. Cell 86:147–157 (1996)

    Article  PubMed  CAS  Google Scholar 

  31. Yang J., Liu X., Bhalla K., et al. Science 275:1129–1132 (1997)

    Article  PubMed  CAS  Google Scholar 

  32. Kim C.N., Wang X., Huang Y., et al. Cancer Res. 57:3115–3120 (1997)

    PubMed  CAS  Google Scholar 

  33. Kharbanda S., Pandey P., Schofield L., Isreals S., Roncinskel L. Proc. Natl. Acad. Sci. USA 94:6939–6942 (1997)

    Article  PubMed  CAS  Google Scholar 

  34. Wang H.G., Rapp U.R., Reed J.C. Cell 87:1–20 (1996)

    Article  CAS  Google Scholar 

  35. Susin S.A., Zamzami N., Larochette N., et al. Exp. Cell Res. 236:397–403 (1997)

    Article  PubMed  CAS  Google Scholar 

  36. Susin S.A., Zamzami N., Castedo M., Hirsch T., Marchetti P., Macho A., Dongas E., Geuskens M., Kroemer G. J. Exp. Med. 184:1331–1342 (1996)

    Article  PubMed  CAS  Google Scholar 

  37. Bernardi P., Broekemeier K.M., Pfeiffer D.R. J. Bioenerg. Biomembr. 26:509–517 (1994)

    Article  PubMed  CAS  Google Scholar 

  38. Hunter D.R., Haworth R.A. Arch. Biochem. Biophys. 195:453–459 (1979)

    Article  PubMed  CAS  Google Scholar 

  39. Nicoli A., Petronilli V., Bernardi P. Biochemistry 32:4461–4465 (1993)

    Article  Google Scholar 

  40. Steller H. Science 267:1445–1449 (1995)

    Article  PubMed  CAS  Google Scholar 

  41. Raff M.C. Nature 356:397–400 (1992)

    Article  PubMed  CAS  Google Scholar 

  42. Wyllie A.H., Kerr J.F., Currie A.R. Int. Rev. Cytol. 68:251–306 (1980)

    PubMed  CAS  Google Scholar 

  43. Shimizu S., Eguchi Y., Kamiike W., Itoh Y., et al. Cancer Res. 56:2161–2166 (1996)

    PubMed  CAS  Google Scholar 

  44. Ancarcrona M., Dypbukt J.M., Bonfoco E., et al. Neuron 15:961–973 (1995)

    Article  Google Scholar 

  45. Leist M.F., Gantner F., Kunstle G., et al. Mol. Med. 2:109–124 (1996)

    PubMed  CAS  Google Scholar 

  46. Leist M., Gantner F., Bohlinger I. Am. J. Pathol. 146:1220–1234 (1995)

    PubMed  CAS  Google Scholar 

  47. Bonfoco E., Dypbukt J.M., Aukracronera M., Burkitt M., et al. J. Biol. Chem. 269:30533–30560 (1994)

    Google Scholar 

  48. Zamzami N., Marchetti P., et al. J. Exp. Med. 181:1661–1672 (1995)

    Article  PubMed  CAS  Google Scholar 

  49. Hockenbery D.M., Oltvai X.M., Yin X.M., Milliman C.L., Korsmeyer S.J. Cell 75:241–251 (1993)

    Article  PubMed  CAS  Google Scholar 

  50. Hennet T.C., Richter C., Peterhaus E. Biochem. J. 189:587–592 (1993)

    Google Scholar 

  51. Smets L.A., Van der Berg J., et al. Blood 5:1613–1619 (1994)

    Google Scholar 

  52. Ramirez R., Carracedo J., Zamzami N., Castedo M., Kroemer G. J. Exp. Med. 180:1147–1152 (1994)

    Article  PubMed  CAS  Google Scholar 

  53. Bouilland F., Arechaga P.X., et al. EMBO (Eur. Mol. Biol. Organ.) J. 13:1990–1997 (1994)

    Google Scholar 

  54. Gonzales D.H., Neupert W. J. Bioenerg. Biomembr. 22:753–768 (1990)

    PubMed  CAS  Google Scholar 

  55. Wigdal S.S., Kirkland R.A., Franklin J.L., Haak-Frendscho M. J. Neurochem. 82:1029–1038 (2002)

    Article  PubMed  CAS  Google Scholar 

  56. Nur-E-Kamal A., Cross S.R., Pan Z., Balklava Z., Ma J., Lin L.F. J. Biol. Chem. 279:24911–24914 (2004)

    Article  PubMed  CAS  Google Scholar 

  57. Kanntt A., Lancaster C. R.D., Michel J. J. Bioenerg. Biomembr. 30:1–6 (1998)

    Article  Google Scholar 

  58. Goping I.S., Gross A., Lavoie J.N., et al. J. Cell Biol. 143:207–215 (1998)

    Article  PubMed  CAS  Google Scholar 

  59. Hsu Y.T., Wolter K.G., Youle R. J. Proc. Natl. Acad. Sci. USA 94:3668–3672 (1997)

    Article  CAS  Google Scholar 

  60. Bouilland F., Arechaga P.X., et al. EMBO (Eur. Mol. Biol. Organ.) J. 13:1990–1997 (1994)

    Google Scholar 

  61. Gonzales D.H., Neupert W. J. Bioenerg. Biomembr. 22:753–768 (1990)

    PubMed  CAS  Google Scholar 

  62. Zamzami N., Susin S.A., Marchetti P., Hirsch T., Gomez-Monterrey I., Castedo M.J., Kroemer G. Exp. Med. 183:1533–1544 (1996)

    Article  CAS  Google Scholar 

  63. Lazebnik Y.A., Kaufmann S.H., Desnoyers S., Poirier G.G., Earnshaw W.C. Nature 371:346–347 (1994)

    Article  PubMed  CAS  Google Scholar 

  64. Kaufmann S., Desnoyer S., Ottaviano Y., Davidson N., Poirier G. Cacer Res. 53:3976–3985 (1993)

    CAS  Google Scholar 

  65. Casciola-Rosen L., Miller D., Anhalt D., Rosen A. J. Biol. Chem. 8269:30757–30760 (1994)

    Google Scholar 

  66. Herbert L., Pandey S., Wang E. Exp. Cell Res. 201:10–18 (1994)

    Article  Google Scholar 

  67. Oberhammer F.A., Hochegger K., Froschl G. J. Cell Biol. 126:827–837 (1994)

    Article  PubMed  CAS  Google Scholar 

  68. Fernandes-Alnemri T., Littwack G., Alnemri E. Cancer Res. 55:2737–2742 (1995)

    PubMed  CAS  Google Scholar 

  69. Bruno S., Bino G.D., Lassota P., Giaretti W., Darzynkiewicz Z. (1992)

    Google Scholar 

  70. Sarin A., Adams D., Henkart P. J. Exp. Med. 178:1693–1700 (1993)

    Article  PubMed  CAS  Google Scholar 

  71. Ray C., Black R., Kronheim S., Greenstreet T.A., Sleath P.R., Salvesen G.S., Pickup D.J. Cell 69:597–604 (1992)

    Article  PubMed  CAS  Google Scholar 

  72. Komimayama T., Ray C., Pickup D. J. Biol. Chem. 269:19331–19337 (1994)

    Google Scholar 

  73. Zou H., Henzel W.J., Liu X.S., Lutschg A., Wang X.D. Cell 90(3):405–413 (1997)

    Article  PubMed  CAS  Google Scholar 

  74. Skulachev V.P. Rev. Biophys. 29:169–202 (1996)

    Article  CAS  Google Scholar 

  75. White E. Nature 284:555–556 (1996)

    Google Scholar 

  76. Kerr J.F.R. J. Pathol. 105:13–20 (1971)

    Article  PubMed  CAS  Google Scholar 

  77. Wyllie A.H. Nature 284:555–556 (1980)

    Article  PubMed  CAS  Google Scholar 

  78. Schlegel J., Peters I., Orrenius S., Miller D.K., Thomberry N.A., Yamin T.T., Nicholson W.D. J. Biol. Chem. 271:1841–1844 (1996)

    Article  PubMed  CAS  Google Scholar 

  79. Duan H., Chinnaiyan A.M., Hudson P.L., Wing J.P., He W., Dixit V.M. J. Biol. Chem. 271:1621–1625 (1996)

    Article  PubMed  CAS  Google Scholar 

  80. Tewari M., Quan L., O’Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Cell 81:801–809 (1995)

    Article  PubMed  CAS  Google Scholar 

  81. Nicholson W.D., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., Gareau Y., Griffin P.R., Labelle M., Lazebnik Y.A., Munday N.A., Raju S.M., Smulsons M.E., Yamin T.T., Yu V.L., Miller D.K. Nature 376:37–43 (1995)

    Article  PubMed  CAS  Google Scholar 

  82. Hengartner M.O., Horvitz R.H. Cell 76:665–676 (1994a)

    Google Scholar 

  83. Hengartner M.O., Ellis R.E., Horcitz R.H. Nature 356:494–499 (1992)

    Article  PubMed  CAS  Google Scholar 

  84. Yuan J.Y., Horvitz R.H. Dev. Biol. 138:33–41 (1990)

    Article  PubMed  CAS  Google Scholar 

  85. Yang J., et al. Science 275:1129–1132 (1997)

    Article  PubMed  CAS  Google Scholar 

  86. Monaghan P., Robertson D., Amos T.A.S., Dyer M.J.S., Mason D.Y., Greaves M.F. J. Histochem. Cytochem 40:1819–1825 (1992)

    PubMed  CAS  Google Scholar 

  87. Krajewski S., Tanaka S., Takayama S., Schibler M.J., Fenton W., Reed J.C. Cancer Res. 53:4701–4714 (1993)

    PubMed  CAS  Google Scholar 

  88. Fernandes-Alnemri T., Litwack G., Alnemri E.S. J. Biol. Chem. 269:30761–30764 (1994)

    PubMed  CAS  Google Scholar 

  89. Wang X., Zelenski N.G., Yang J., Sakai J., Brown M.S., Goldstein J.L. EMBO J. 15:1012–1020 (1996)

    PubMed  CAS  Google Scholar 

  90. Wang X., Briggs M.R., Hua X., Yokoyama C., Goldstein J.L., Brown M.S. J. Biol. Chem. 268:14497–14504 (1993)

    PubMed  CAS  Google Scholar 

  91. Boveris A., Chance B. Biochem. J. 134:707–716 (1973)

    PubMed  CAS  Google Scholar 

  92. Turrens J.F. Biosci. Rep. 17:3–8 (1997)

    Article  PubMed  CAS  Google Scholar 

  93. Tangeras A., Flatmark T., Backtrom D., Ehrenberg A. Biochim. Biophys. Acta 589:162–175 (1980)

    Article  PubMed  CAS  Google Scholar 

  94. Minotti G., Aust S.D. Free Radic. Biol. Med. 3:379–387 (1987)

    Article  PubMed  CAS  Google Scholar 

  95. Hermes-Lima M., Castilho R.F., Meinicke A.R., Cercesi A.E. Mol. Cell Biochem. 145:53–60 (1995)

    Article  PubMed  CAS  Google Scholar 

  96. Liu S.S. Biosc. Rep. 17:259–272 (1997)

    Article  CAS  Google Scholar 

  97. Turrens J.F., Boveris A. Biochem. J. 191:421–427 (1980)

    PubMed  CAS  Google Scholar 

  98. Cadenas E., Boveris A., Ragan C.J., Stoppani A.O.M. Arch. Biochem. Biophys. 180:248–257 (1977)

    Article  PubMed  CAS  Google Scholar 

  99. Sutton H.C., Einterbourn C.C. Free Radic. Biol. Med. 6:53–60 (1989)

    Article  PubMed  CAS  Google Scholar 

  100. Halliwell B., Gutteridge J.M.C. Free Radicals in biology and medicine. Oxford: Oxford Univ. Press. (1989)

    Google Scholar 

  101. Watabe S., Hiroi T., Yamamoto Y., Fujioka Y., Hasegawa H., Yago N., Takahashi S.Y. Eur. J. Biochem. 249:52–60 (1997)

    Article  PubMed  CAS  Google Scholar 

  102. Guidot D.M., Repine J.E., Kitlowski A.D., Flores S.C., Nelson S.K., Wright R.M., McCord J.M. J. Clin. Invest. 96:1131–1136 (1995)

    PubMed  CAS  Google Scholar 

  103. Fridovich I. J. Biol. Chem. 272:18515–18517 (1997)

    Article  PubMed  CAS  Google Scholar 

  104. Radi R., Turrens J.F., Chang L.Y., Bush K.M., Crap J.D., Freeman B.A. J. Biol. Chem. 261:14081–14024 (1991)

    Google Scholar 

  105. Chance B., Sies H., Boveris A. Physiol. Rev. 59:527–605 (1979)

    PubMed  CAS  Google Scholar 

  106. Castilho R.F., Kowaltowski A.J., Meinicke A.R., Bechara E.J.H., Vercesi A.E. Free Radic. Biol. Med. 18:479–486 (1995)

    Article  PubMed  CAS  Google Scholar 

  107. Vercesi A.E., Kowaltowski A.J., Grijalba M.T., Meinicke A.R., Castilho R.F. Biosc. Rep. 17:43–53 (1997)

    Article  CAS  Google Scholar 

  108. Kowaltowski A.J., Castilho R.F., Vercesi A.E. FEBS Lett. 378:150–152 (1996)

    Article  PubMed  CAS  Google Scholar 

  109. Gunter T.E., Gunter K.K., Shen S.S., Gavin C.E. Am. J. Physiol. 267 (Cell Physiol 36): C313–C339 (1994) Bernardi P. Biochim. Biophys. Acta 1275:5–9 (1996)

    PubMed  CAS  Google Scholar 

  110. Crompton M., Andreeva L. Basic Res. Cardiol. 88:513–523 (1993)

    Article  PubMed  CAS  Google Scholar 

  111. Turrens J.F., Freeman B.A., Levit J.Z.G., Crapo J.D. Arch. Biochem. Biophys. 217:401–416 (1982)

    Article  PubMed  CAS  Google Scholar 

  112. Petronilli V., Costantini P., Scorrano L., Colonna R., Passamonti S., Bernardi P. J. Biol. Chem. 269:16638–16642 (1994)

    PubMed  CAS  Google Scholar 

  113. Chernyak B.V., Bernardi P. Eur. J. Biochem. 238:623–630 (1996)

    Article  PubMed  CAS  Google Scholar 

  114. Crompton M., Virji S., Ward J.M. Eur. J. Biochem. 258:729–735 (1998)

    Article  PubMed  CAS  Google Scholar 

  115. Davis K.J. Biochem. Soc. Symp. 61:1–31 (1995)

    Google Scholar 

  116. Bernardi P. Biochim. Biophys. Acta 1275:5–9 (1996)

    Article  PubMed  Google Scholar 

  117. Zoratti M., Szabo T. J. Bioenerg. Biomembr. 26:543–553 (1994)

    Article  PubMed  CAS  Google Scholar 

  118. Duchen M.R., McGuinness O., Brown L., Crompton M. Cardiovasc. Res. 27:1780–1794 (1993)

    Google Scholar 

  119. Griffiths E., Halestrap A.P. Biochem. J. 307:96–98 (1995)

    Google Scholar 

  120. DiLisa F., Blank P.S., Colonna R., Gambassi G., Silverman H.S., Stem M.D., Hansford R.G. J. Physiol. (London) 486:1–13 (1995)

    CAS  Google Scholar 

  121. Imberti R., Nieminen A.L., Herman B., Lemasters J.J. J. Pharmacol. Exp. Ther. 265:392–400 (1993)

    PubMed  CAS  Google Scholar 

  122. Brown R.H. Curr. Opinion Neurol. 8:373–378 (1995)

    Article  CAS  Google Scholar 

  123. Westendorp M.O., Shatrov V.A., Schulze-Olstoff K., Frank R., Kraft M., Los M., Krammer P.H., Droge W., Lehmann V. EMBO J. 14:546–554 (1995)

    PubMed  CAS  Google Scholar 

  124. Crompton M., Elliuger H., Costi A. Biochem J. 255:357–360 (1988)

    PubMed  CAS  Google Scholar 

  125. Crompton M., Costi A. Biochem J. 266:33–39 (1990)

    PubMed  CAS  Google Scholar 

  126. Halliwell B., Chirico S. Am. J. Clin. Nutr. 57:7155–7255 (1993)

    Google Scholar 

  127. Kappus A. In: Sies H. ed., Oxidative Stress London: Academic Press Inc. (1985)

    Google Scholar 

  128. Vladimirov Y.A., Olenev V.I., Suslova T.B., Cheremisina Z.P. Adv. Lipid Res. 17:173–249 (1980)

    PubMed  CAS  Google Scholar 

  129. Masini A., Trenti T. Biochim. Biophys. Acta 810:20–26 (1985)

    Article  PubMed  CAS  Google Scholar 

  130. Castilho R.F., Meinicke A.R., Almeida A.M., Hermes-Lima M., Vercesi A.E. Arch. Biochem. Biophys. 308:158–163 (1994)

    Article  PubMed  CAS  Google Scholar 

  131. Nautes I.L., Cilento G., Bechara E.J.H., Vercesi A.E. Photochem. Photobiol. 62:522–527 (1995)

    Google Scholar 

  132. Kowaltowski A.J., Castilho R.F., Bechara E.J.H., Vercesi A.E. J. Biol. Chem. 271:2929–2934 (1996)

    Article  PubMed  CAS  Google Scholar 

  133. Pryor W.A., Squadrito G.L. Am. J. Physiol. 268:699–722 (1995)

    Google Scholar 

  134. Gadelha F.R., Thomson L., Fagian M.M., Costa A.D.T., Radi R., Vercesi A.E. Arch. Biochim. Biophys. 345:243–250 (1997)

    Article  CAS  Google Scholar 

  135. Henkart P.A., Grinstein S.J. Exp. Med. 183:1293–1295 (1996)

    Article  CAS  Google Scholar 

  136. Marchetti P., Catedo M., Susin S.A., Zamzami N., Hirsch T., Macho A., Haeffner A., Hirch F., Genskens M., Kroemer G. J. Exp. Med. 184:1155–1160 (1996)

    Article  PubMed  CAS  Google Scholar 

  137. Zamzami N., Marchetti P., Castedo M., Hirsch T., Susin S.A., Mass B., Kroemer G. FEBS Lett. 384:53–57 (1996)

    Article  PubMed  CAS  Google Scholar 

  138. Kim C.N., Way X., Huang Y., Ibrado A.M., Lin L., Fang G., Bhalla K. Cancer Res. 57:3115–3120 (1997)

    PubMed  CAS  Google Scholar 

  139. Antonson B., Conti F., Ciavatta A.M., Montessuit S., Lewis S., Martinou I., Bernasconi L., Bernand A., Mermod J.J., Mazzei G., Maundrell K., Gambale F., Sadoul R., Martinon J.C. Science 288:370–373 (1977)

    Google Scholar 

  140. Brunnori M., Guiffre A., et al. Cell Mol. Life Sci. 56:549–557 (1999)

    Article  Google Scholar 

  141. Gauch I. In: Azzi A., Nalecz K.A., Nalecz M.J., Wojtczak L. eds., Anion carriers of mitochondrial membranes. Berlin: Springer-Verlag 133–146 (1989)

    Google Scholar 

  142. Stefanelli C., Bonavita F., Stanic I., Farruggia G., Falicieri C., Calarera C.M., Biochem J. 322:909–917 (1997)

    PubMed  CAS  Google Scholar 

  143. Schweizer M., Richter C. Biochemistry 35:4524–4528 (1996)

    Article  PubMed  CAS  Google Scholar 

  144. Vieira H.L., Belzaq A.S., et al. Oncogene 20:4305–4316 (2001)

    Article  PubMed  CAS  Google Scholar 

  145. Giron-Calle J., Schmid H.H. Biochemistry 35:15440–15446 (1996)

    Article  PubMed  CAS  Google Scholar 

  146. Borutaite V., Morkuniene R., Brown G.C. Biochim. Biophys. Acta 1453:41–18 (1999)

    PubMed  CAS  Google Scholar 

  147. Scarlett J.L., Packer M.A., Porteous C.M., Murphy M.P. Biochem. Pharmacol. 52:1047–1055 (1996)

    Article  PubMed  CAS  Google Scholar 

  148. Aulak K.S., Miyagi M., et al. Proc. Natl. Acad. Sci. USA 98:12056–12061 (2001)

    Article  PubMed  CAS  Google Scholar 

  149. Richter C., Schweizer M., Cossarizza A., Franceshi C. FEBS Lett. 371:107–110 (1996)

    Article  Google Scholar 

  150. Leist M., Single B., Castoldi A.F., Kuhule S., Nicotera P. J. Exp. Med. 185(8):1481–1486 (1997)

    Article  PubMed  CAS  Google Scholar 

  151. Simbula G., Glascott P.A., Akita A., Hock J.B., Farber J.L. Am. J. Physiol 273:C479–C488 (1997)

    PubMed  CAS  Google Scholar 

  152. Sanchez-Alcazart J.A., Ruiz-Callego J., Hermandez-Munot I., Sanchez-Pobre P., de la Torre P., Siles-Rivas E., Garcia I., Kaplan O., Munoz-Yage M.T., Solis-Herruzo J.A. J. Biol. Chem 272:30167–30177 (1997)

    Article  Google Scholar 

  153. Lemasters J.J., Neiminen A.L., Quian T., Trost L.C., Herman B. Mol. Cell Biochem. 174:159–165 (1997)

    Article  PubMed  CAS  Google Scholar 

  154. Pastorino J.G., Sinder J.W., Hoek J.B., Farber J.L. Am. J. Physiol. 268:C676–C685 (1995)

    PubMed  CAS  Google Scholar 

  155. Pastorino J.G., Simula G., Yamamoto K., Glascott P.A., Rothman R.J., Farber J.L., Simula G., Yamomoto K., Glascott P.A., Rothman R.J., Farber J.L. J. Biol. Chem 271(47):29792–29798 (1996)

    Article  PubMed  CAS  Google Scholar 

  156. Petronelli V., Costantini P., Scorrano L., Colonna R., Passamonti S., Bernardi P. J. Biol. Chem. 269(24):16638–16642 (1994)

    Google Scholar 

  157. Salet C., Moreno G., Ricchelli F., Bernardi P. J. Biol. Chem. 272(35):21938–21943 (1997)

    Article  PubMed  CAS  Google Scholar 

  158. Eriksson O., Fontaine E., Petrollini V., Bernardi P. FEBS Lett. 409(3):361–364 (1997)

    Article  PubMed  CAS  Google Scholar 

  159. Hortelano S., Dallaporta B., Zamzami N., Hirch T., Susin S.A., Mazzo I., Vosca L., Kroemer G. FEBS Lett. 410:373–377 (1997)

    Article  PubMed  CAS  Google Scholar 

  160. Hockenbery D., Nunez G., Milliman C., Schewiber R.D., Korsmeyer S.J. Nature 348:334–336 (1990)

    Article  PubMed  CAS  Google Scholar 

  161. Kane F.J., Sarafian T.A., Anton R., Hahn H., Gralla E.B., Valentine J.S., Ord T., Bredesen D.E. Science 262:1274–1277 (1993)

    Article  PubMed  CAS  Google Scholar 

  162. Buttke T.M., Sandstrom P.A. Immunol. Today 15:7–10 (1994)

    Article  PubMed  CAS  Google Scholar 

  163. Goosens V., Grooten J., De Vos K., Fiers W. Proc. Natl. Acad. Sci. USA 92:8115–8119 (1995)

    Article  Google Scholar 

  164. Jacobson M.D., Raff M.C. Nature 374:814–816 (1995)

    Article  PubMed  CAS  Google Scholar 

  165. Muschel R.J., Bernhard E.J., Gazza L., McKenna W.G., Koch C.J. Cancer Res. 55:995–998 (1995)

    PubMed  CAS  Google Scholar 

  166. Shimizu S., Eguchi Y., Kosaka Y., Kamike W., Matsuda H., Tsujimoto Y. Nature 374:811–813 (1995)

    Article  PubMed  CAS  Google Scholar 

  167. Jacobson M.D. Trends Biochem. Sci. 21:83–86 (1996)

    PubMed  CAS  Google Scholar 

  168. Yang E., Korsmeyer S.J. Blood 88:386 (1996)

    PubMed  CAS  Google Scholar 

  169. Xie K., Huang S., et al. Cancer Immunol. Immunother 43:109 (1996)

    Article  PubMed  CAS  Google Scholar 

  170. Messmer U.K., Reed U.K., Brune B. J. Biol. Chem. 271:20192 (1996)

    Article  PubMed  CAS  Google Scholar 

  171. Zhivotovski B., Orrenius S., Brustugun O.T., Doskeland S.O. Nature 391:449 (1998)

    Article  Google Scholar 

  172. Malins D.C., Haimanot R. Cancer Res. 51:5430–5432 (1991)

    PubMed  CAS  Google Scholar 

  173. Olinski R., Zastawny T., Skokowski J., Zegarski W., Disdaroglu M. FEBS Lett. 309:193–198 (1992)

    Article  PubMed  CAS  Google Scholar 

  174. Olinski R., Zastawny T., Foksinski M., Barecki A., Dizdaroglu M. Free Radic. Biol. Med. 18:807–813 (1995)

    Article  PubMed  CAS  Google Scholar 

  175. Jaruga P., Zastawny T.H., Skokowski J., Olinski R., Dizdaroglu M. FEBS Lett. 341:59–64 (1994)

    Article  PubMed  CAS  Google Scholar 

  176. Berstain H., Gensler H.L. Biochem. Biophys. Acta 1271(1):165–170 (1995)

    Google Scholar 

  177. Gerschenson M., Low R.L., Loehr J. J. Mol. Cell Cardiol. 26:31–40 (1994)

    Article  PubMed  CAS  Google Scholar 

  178. deHaan J.B., Wolvetang E.J., Cristiano F., Iannello R., Bladier C., Kelner M., Kola M. Adv. Pharmacol. 38:379–387 (1997)

    CAS  Google Scholar 

  179. de Haan J.B., Cristiano F., Iannello R.C., Kola I. Biochem. Mol. Biol. Int. 35:1281–1292 (1995)

    PubMed  Google Scholar 

  180. de Haan J.B., Newman J.D., Kola I. Brain Res. Mol. Brain Res. 13:179–186 (1992)

    PubMed  Google Scholar 

  181. Zhang Y., Marcillat O., Guillivi C., Ernster L., Davies K.J.A. J. Biol. Chem. 265:16330–16336 (1990)

    PubMed  CAS  Google Scholar 

  182. Farber J.L., Kyle M.E., Coleman J.B. Lab. Invest. 62:670–679 (1990)

    PubMed  CAS  Google Scholar 

  183. Bindoli A. Free Rad. Biol. Med. 5:247–261 (1998)

    Article  Google Scholar 

  184. Davis K.J.A., Doroshow J.H. J. Biol. Chem. 261:3060–3067 (1986)

    Google Scholar 

  185. Crawford D.R., Wang Y., Schools G.P., Kocheiser J., Davis K.J.A. Free Radic. Biol. Med. 22:551–559 (1997)

    Article  PubMed  CAS  Google Scholar 

  186. Wiese A.G., Pacific R.E., Davis K.J.A. Arch. Biochem. Biophys. 318:231–240 (1995)

    Article  PubMed  CAS  Google Scholar 

  187. Crawford D.R., Lauzon R.J., Wang Y., Mazurkiewicz J.E., Davies K.J.A. Free Radic. Biol. Med. 22:1295–1300 (1997)

    Article  PubMed  CAS  Google Scholar 

  188. Vincent F., Corral-Debrinski M., Adolphe M. J. Cell. Physiol. 158:128–132 (1994)

    Article  PubMed  CAS  Google Scholar 

  189. Kristal B.S., Chen J., Yu B.P. Free Radic. Biol. Med. 16:323–329 (1994)

    Article  PubMed  CAS  Google Scholar 

  190. Marcillat O., Zhang Y., Lin S.W., Davies K.J.A. Biochem. J. 254:667–683 (1998)

    Google Scholar 

  191. Wolosker H., Panizzutti R., Engelender S. FEBS Lett. 392:274–276 (1996)

    Article  PubMed  CAS  Google Scholar 

  192. Konorev E.A., Kalyanazaman B. FEBS Lett. 427:171–174 (1998)

    Article  PubMed  CAS  Google Scholar 

  193. Brown G.C. Biochim. Biophys. Acta 1504:46–57 (2001)

    Article  PubMed  CAS  Google Scholar 

  194. Cooper C.E. Trends Biochem. Sci. 27:33–39 (2002)

    Article  PubMed  CAS  Google Scholar 

  195. Brunnori M., Guiffre A., et al. Cell. Mol. Life Sci. 56:549–557 (1999)

    Article  Google Scholar 

  196. Cassina A., Radi R. Arch. Biophys. Biochem. 328:309–316 (1996)

    Article  CAS  Google Scholar 

  197. Cleeter M.W.J., Cooper J.M., et al. FEBS Lett. 345:50–54 (1994)

    Article  PubMed  CAS  Google Scholar 

  198. Brudvig O.W., Stevens O.H., Chan O.I. Biochemistry 19:5275–5285 (1980)

    Article  PubMed  CAS  Google Scholar 

  199. Drapier J.C., Hibbs Jr. J.B. J. Clin. Invest. 78:790–797 (1986)

    PubMed  CAS  Google Scholar 

  200. Wharton M., Granger D.L., Durck D.T. J. Immunol. 141:1311–1317 (1988)

    PubMed  CAS  Google Scholar 

  201. Stadler J., Curran R.D., Ochoa J.B., et al. Arch. Surg. 126:186–191 (1991)

    PubMed  CAS  Google Scholar 

  202. Brown G.C., Cooper C.E. FEBS Lett. 356:295–298 (1994)

    Article  PubMed  CAS  Google Scholar 

  203. Clementi E., Brown G.C., et al. Proc. Natl. Acad. Sci. USA 96:1559–1562 (1999)

    Article  PubMed  CAS  Google Scholar 

  204. Brown G.C., Foxwell N., Moncada S. FEBS Lett. 439:321–324 (1998)

    Article  PubMed  CAS  Google Scholar 

  205. Rotutaite V., Matthias A., et al. Am. J. Physiol. 281:H2256–H2260 (2001)

    Google Scholar 

  206. Richter C., Gogvadze V., et al. Biochem. Biophys. Res. Commun. 205:1143–1150 (1994)

    Article  PubMed  CAS  Google Scholar 

  207. Brown G.C. FEBS Lett. 369:136–139 (1995)

    Article  PubMed  CAS  Google Scholar 

  208. Clementi E., Brown G.C., Feelisch M., Moncada S. Proc. Natl. Acad. Sci. USA 95:7631–7636 (1998)

    Article  PubMed  CAS  Google Scholar 

  209. Riobo N.A., Clementi E., et al. Biochem. J. 359:139–145 (2001)

    Article  PubMed  CAS  Google Scholar 

  210. Granger D.L., Lehninger A.L. J. Cell Biol. 95:527–535 (1982)

    Article  PubMed  CAS  Google Scholar 

  211. Huie R.E., Radmaja S. Free Rad. Res. Commun. 18:195–199 (1993)

    CAS  Google Scholar 

  212. Beckman J.S., Beckman T.W., Chen J. Proc. Natl. Acad. Sci. USA 87:1620–1624 (1990)

    Article  CAS  Google Scholar 

  213. Radi R., Beckman T.W., Bush K.M., Freeman B.A. J. Biol. Chem. 266:4244–4250 (1991)

    PubMed  CAS  Google Scholar 

  214. Koppenol W.H., Pryor W.A., Moreno J.J., Ischiropoulos H., Beckman J.S. Chem. Res. Toxicol. 5:834–842 (1992)

    Article  PubMed  CAS  Google Scholar 

  215. Clementi-Borutaite V., Budriunaite A., Brown G.C. Biochim. Biophys. Acta 1459:405–412 (2000)

    Article  Google Scholar 

  216. Drapier J.C., Hibbs J.B. Jr. J. Immunol. 140:2829–2838 (1988)

    PubMed  CAS  Google Scholar 

  217. Stuehr D.J., Nathan C.F. J. Exp. Med. 169:1543–1555 (1989)

    Article  PubMed  CAS  Google Scholar 

  218. Castro L.A., Rovalinho R.L., et al. Arch. Biochem. Biophys. 359:215–224 (1998)

    Article  PubMed  CAS  Google Scholar 

  219. Brown G.C. Biochim. Biophys. Acta 1411:351–369 (1999)

    Article  PubMed  CAS  Google Scholar 

  220. Vassina A., Radi R. Arch. Biophys. Biochem. 328:309–316 (1996)

    Article  Google Scholar 

  221. Bolanos J.P., Heales S.J.R., et al. J. Neurochem 64:1965–1972 (1995)

    Article  PubMed  CAS  Google Scholar 

  222. Yamamoto T., Maruyama W., et al. J. Neurol. Transm. 109:1–13 (2002)

    Article  CAS  Google Scholar 

  223. Poderoso J.J., Carreras M.C., et al. Arch. Biochem. Biophys. 328:85–92 (1996)

    Article  PubMed  CAS  Google Scholar 

  224. McMillan-Crow L.A., Crow J.P., Kerby J.D., Beckman J.S., Thompson J.A. Proc. Natl. Acad. Sci. USA 93:11853–11858 (1996)

    Article  Google Scholar 

  225. Radi R., Rodriguez M., Castro L., Telleri R. Arch. Biochem. Biophys. 308:89–95 (1994)

    Article  PubMed  CAS  Google Scholar 

  226. Rubbo H., Denicola A., Radi R. Arch. Biochem. Biophys. 308:96–102 (1994)

    Article  PubMed  CAS  Google Scholar 

  227. Szabo C., Salzman A.L. Biochem. Biophys. Res. Commun. 209:739–743 (1995)

    Article  PubMed  CAS  Google Scholar 

  228. Vedia L.M., McDonald B., et al. J. Biol. Chem. 267:24929–24932 (1992)

    Google Scholar 

  229. Packer M.A., Murphy M.P. FEBS Lett. 345:237–240 (1994)

    Article  PubMed  CAS  Google Scholar 

  230. Packer M.A. Eur. J. Biochem 234:231–239 (1995)

    Article  PubMed  CAS  Google Scholar 

  231. Scweizer M., Richter C. Biochemistry 35:4524–4528 (1996)

    Article  Google Scholar 

  232. Nicotera P., Ankarcrona M., et al. Adv. Neurol. 72:95–101 (1997)

    PubMed  CAS  Google Scholar 

  233. Nicotera P., Orrenius S. Ann. NY Acad. Sci. 648:17–27 (1992)

    Article  PubMed  CAS  Google Scholar 

  234. Poderoso J.P., Peralta J.G., et al. Am. J. Physiol. 274:C112–C119 (1998)

    Google Scholar 

  235. Poderoso J.J., Carreras M.C., et al. Free Radic. Biol. Med. 26:925–935 (1999)

    Article  PubMed  CAS  Google Scholar 

  236. Brown G.C. Eur. J. Biochem. 232:188–191 (1995)

    Article  PubMed  CAS  Google Scholar 

  237. Ignarro L.J. ed., Nitric Oxide; Biology and Pathobiology. San Diego: Academic Press (2000)

    Google Scholar 

  238. McBride A.G., Borutaite V., Brown G.C. Biochim. Biophys. Acta 1454:275–288 (1999)

    Google Scholar 

  239. Bernardi P. Biochim. Biophys. Acta 238:623–630 (1999)

    Google Scholar 

  240. Bernardi P., Petronilli V., Di Lisa F., Forte M. Trends Biochem. Sci. 26:112–117 (2001)

    Article  PubMed  CAS  Google Scholar 

  241. Halestrap A.D. Biochem. Soc. Sym. 66:181–203 (1999)

    CAS  Google Scholar 

  242. Takuma K., Phuagphong P., et al. J. Biol. Chem. 276:48093–48099 (2001)

    PubMed  CAS  Google Scholar 

  243. Viveira H.L., Belzacq A.S., et al. Oncogene 20:4305–4316 (2001)

    Article  CAS  Google Scholar 

  244. Piantadosi C.A., Tatro C.A., Whorton A.R. Nitric Oxide 6:45–60 (2002)

    Article  PubMed  CAS  Google Scholar 

  245. Ghafourifar P., Schenk U., Klein S.D., Richter C. J. Biol. Chem. 274:31185–31188 (1999)

    Article  PubMed  CAS  Google Scholar 

  246. Schmidt H.H.H.W. FEBS Lett. 307:102–107 (1992)

    Article  PubMed  CAS  Google Scholar 

  247. Schmidt H.H.H.W., Walter H.W. Cell 78:919–925 (1994)

    Article  PubMed  CAS  Google Scholar 

  248. Schmidt H.H.H.W., Lohmann S.M., Walter U. Biochim. Biophys. Acta 1178:153–175 (1993)

    Article  PubMed  CAS  Google Scholar 

  249. Messmer U.K., Reimer D.M., Reed J.C., Brune B. FEBS Lett. 384:162–166 (1996)

    Article  PubMed  CAS  Google Scholar 

  250. Stefanelli C., Pignatti C., Tantini B., Stanic I., Bonavita F., Muscari C., Guarnieri C., Clo C., Caldarera C.M. Biochim. Biophys. Acta. 1450(3):406–413 (1999)

    Google Scholar 

  251. Messmer U.K., Brune B. Biochem. J. 319:299–305 (1996)

    PubMed  CAS  Google Scholar 

  252. Balakirev M.Y., Khramtsov V.V., Zimmer G. Eur. J. Biochem. 246:710–718 (1997)

    Article  PubMed  CAS  Google Scholar 

  253. Loweth A.C., Williams G.T., Scarpello J.H.B., Morgan N.G. FEBS Lett. 400:285–288 (1997)

    Article  PubMed  CAS  Google Scholar 

  254. Ushmorov A., Ratter F., et al. Blood 93:2342–2352 (1999)

    PubMed  CAS  Google Scholar 

  255. Richter C. Biosci. Rep. 17:53–66 (1997)

    Article  PubMed  CAS  Google Scholar 

  256. Gotz C., Montenarch M. Rev. Physiol. Biochem. Pharmacol. 127:65–95 (1995)

    Google Scholar 

  257. Caelles C., Helmberg A., Karin M. Nature (London) 370:220–223 (1994)

    Article  CAS  Google Scholar 

  258. Miyashita T., Krajewski S., et al. Oncogene 9:1799–1805 (1994)

    PubMed  CAS  Google Scholar 

  259. Jun C.D., Choi B.M., Ryu H., et al. J. Immunol. 153:3684–3689 (1994)

    PubMed  CAS  Google Scholar 

  260. So H.S., Park R.K., Kim M.S., et al. Biochem. Biophys. Res. Commun. 247:809–813 (1998)

    Article  PubMed  CAS  Google Scholar 

  261. Jun C.D., Oh C.D., Kwak H.J., et al. J. Immunol. 162:3395–3401 (1999)

    PubMed  CAS  Google Scholar 

  262. Takeda Y., Tashim M., Takahashi A., Wchiyama T., Okazaki T. J. Biol. Chem. 274:10654–10660 (1999)

    Article  PubMed  CAS  Google Scholar 

  263. Verheij M., Bose R., Lin X.H., Yao B., Jarvis W.D., Grant S., Birrer M.J., et al. Nature 380:75–79 (1996)

    Article  PubMed  CAS  Google Scholar 

  264. Di Nardo A., Benassi L., Magnoni C., Cossauzza A., Seidenari S., Giannetti A. Br. J. Dermatol. 143:491–497 (2000)

    Article  PubMed  Google Scholar 

  265. Kim Y.M., de Vera M.E., Watkins S.C., Billiar T.R. J. Biol. Chem. 272:1402–1411 (1997)

    Article  PubMed  CAS  Google Scholar 

  266. Kim Y.M., Bergonia H., Lancaster J.R. FEBS Lett. 374:228–232 (1995)

    Article  PubMed  CAS  Google Scholar 

  267. Kim Y.M., Chung H.T., Kim S.S., Han J.A., Yoo Y.M., Kim K.M., Lee G.H., Yun H.Y., Green A., Li J., Simmons R.L., Billiar T.R. J. Neurosci 19:6740–6747 (1999)

    PubMed  CAS  Google Scholar 

  268. DeNadal C., Sestilli P., Cantoni O., Lievremont J.P., Sciorati C., et al. Proc. Natl. Acad. Sci. USA 97:5480–5485 (2000)

    Article  Google Scholar 

  269. Kim Y.M., Talanian R.V., Billiar T.K. J. Biol. Chem. 272:31138–31148 (1997)

    Article  PubMed  CAS  Google Scholar 

  270. Genaro A.M., Hortelano S., Alvarez A., Martinez C., Bosca L. J. Clin. Invest. 95:1884–1890 (1995)

    PubMed  CAS  Google Scholar 

  271. Li J., Yang S., Billiar T.R. J. Biol. Chem. 275:13026–13034 (2000)

    Article  PubMed  CAS  Google Scholar 

  272. Kim Y.M., Kim T.H., Chung H.T., Talanian R.V., Yin Y.M., Billiar T.R. Hepatology 32:770–778 (2000)

    Article  PubMed  CAS  Google Scholar 

  273. Kim Y.M., Chung H.T., Simmons R.L., Billiar T.R. J. Biol. Chem. 275:10954–10961 (2000)

    Article  PubMed  CAS  Google Scholar 

  274. Souza J.M., Radi R. Arch. Biochem. Biophys. 360:187–194 (1998)

    Article  PubMed  CAS  Google Scholar 

  275. Leist M., Single B., et al. Exp. Cell Res. 249:396–403 (1999)

    Article  PubMed  CAS  Google Scholar 

  276. Bal-Price A., Brown G.C. J. Neurochem. 75:1455–1464 (2000)

    Article  PubMed  CAS  Google Scholar 

  277. Hibbs J.B., Jr. Taintor R.R., et al. Biochem. Biophys. Res. Commun. 157:87–94 (1988)

    Article  PubMed  CAS  Google Scholar 

  278. Szabo C. Eur. J. Pharmacol. 350:1–19 (1998)

    Article  PubMed  CAS  Google Scholar 

  279. Yu S.W., Wang H., Poitres M.F., Coombs C., Bowers W.J., et al. Science 297:259–263 (2002)

    Article  PubMed  CAS  Google Scholar 

  280. Borutaite V., Morkuniene R., Brown G.C. FEBS Lett. 467:155–159 (2000)

    Article  PubMed  CAS  Google Scholar 

  281. Moriya R., Uehara T., Momura Y. FEBS Lett. 484:253–260 (2000)

    Article  PubMed  CAS  Google Scholar 

  282. Yabuki M., Tsusui K., et al. Free Radic. Res. 32:507–514 (1999)

    Article  Google Scholar 

  283. Uchara T., Kikuchi Y., Nomura Y. J. Neurochem. 72:196–205 (1999)

    Article  Google Scholar 

  284. Bosca L., Hortelano S. Cell Signal. 11:239–244 (1999)

    Article  PubMed  CAS  Google Scholar 

  285. Shidoji Y., Hayashi K., et al. Biochem. Biophys. Res. Commun. 264:343–347 (1999)

    Article  PubMed  CAS  Google Scholar 

  286. Brune B., vonKnethen A., Sandan K.B. Cell Death Differ. 6:969–975 (1999)

    Article  PubMed  CAS  Google Scholar 

  287. Tamatani M., Ogawa S., Niitsu Y., Tohyama M. J. Neurochem. 71:1588–1596 (1998)

    Article  PubMed  CAS  Google Scholar 

  288. Ghatan S., Larner S., et al. J. Cell Biol. 150:335–347 (2000)

    Article  PubMed  CAS  Google Scholar 

  289. Kawahara K., Oyadomari S., et al. FEBS Lett. 506:135–139 (2001)

    Article  PubMed  CAS  Google Scholar 

  290. Oyadomari S., Takeda K., et al. Proc. Natl. Acad. Sci. USA 98:10845–10850 (2001)

    Article  PubMed  CAS  Google Scholar 

  291. Nomura K., Imai H., et al. J. Biol. Chem. 274:29294–29302 (1999)

    Article  PubMed  CAS  Google Scholar 

  292. Mikhailov V., Mikhailova M., et al. J. Biol. Chem. 276:18361–18374 (2001)

    Article  PubMed  CAS  Google Scholar 

  293. Kiebish M.A., Seyfried T.N. Absence of pathogenic mitochondrial DNA mutations in mouse brain in tumors. BMC cancer, 5:102, 1–8 (2005)

    Google Scholar 

  294. Wolstenholme D.R. Animal mitochondrial DNA: Structure and evolution. Int. Rev. Cytol. 141:173–216 (1992)

    Article  PubMed  CAS  Google Scholar 

  295. Barrell B.G., Bankier A.T., Drouin J. A different genetic code in human mitochondria. Nature, 282:189–194 (1979)

    Article  PubMed  CAS  Google Scholar 

  296. Neckelmann N., Li K., Wade R.P., Shuster R., Wallace D.C. cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes. Proc. Natl. Acad. Sci. USA 84:7580–7584 (1987).

    Google Scholar 

  297. Wallace D.C., Ye J.H., Neckelmann S.N., Singh G., Webster K.A., Greenberg B.D. Sequence analysis of cDNAs for the human and bovine ATP synthase beta subunit: mitochondrial DNA genes sustain seventeen times more mutations. Curr. Genet. 12:81–90 (1987).

    Article  PubMed  CAS  Google Scholar 

  298. Allen J.A., Coombs M.M. Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA. Nature 287:244–245 (1980).

    Article  PubMed  CAS  Google Scholar 

  299. Shidara Y., Yamagata K., et al. Positive contribution of pathogenic mutations in the mitochondrial genome to the promotion of cancer by prevention from apoptosis. Cancer Res. 65(5):1655–1663 (2005)

    Article  PubMed  CAS  Google Scholar 

  300. Cote C., Boulet D., Poirier J. J. Biol. Chem. 265:7532–7538 (1990)

    PubMed  CAS  Google Scholar 

  301. Neupert W., Hartl F.U., Craig E.A., Pfanner, N. Cell. 63:447–450 (1990).

    Article  PubMed  CAS  Google Scholar 

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Stavridis, J.C. (2008). Mitochondria: Structure, Function and Relationship with Carcinogenesis. In: Oxidation: The Cornerstone of Carcinogenesis. Springer, Dordrecht. https://doi.org/10.1007/978-1-4020-6704-4_4

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