Post-Radiated and Post-Stressed Volatile Secretions: Secondary Immune and Behavioral Reactions in Groups of Animals
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It was shown that the irradiated mice gave off with urine immunosuppressive components which possessed of high volatility. With their help even the one irradiated individual can induce in intact mice the disturbance of immunity and alteration of number of blood cells. Moreover, the predominant mouse from exposed group of mice also was capable to elicit disturbance of immunity in next group of intact animals. The same effects could be received by transfer of the urine samples from irradiated mice or from intact mice exposed with urine of irradiated animals to the box with intact individuals. It was established that ionizing radiation (4–6 Gy) of male mice increase their scent attractiveness to intact singenic male conspecifics. The carried out experiments have shown existence of the mediated by volatile chemosignals mechanism of multiplication second post-radiated disturbances of immunity in the groups of animals. The immunosuppressive volatile components were induced also by stress and some immunodepressants (dexametasone and cyclophosphamide).
KeywordsVolatile Component Bystander Effect Irradiate Mouse Intact Mouse Stressed Mouse
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