Role of Genetic Susceptibility in Environmental Exposure Induced Diseases

Conference paper
Part of the NATO Science for Peace and Security Series book series (NAPSC)

Inherited susceptibility due to a defective gene is a factor in a small percentage of people who develop cancer (<5 %), while induced susceptibility, which is due to the wide variation in individual responses to exogenous agents, is believed to result from the great diversity in responsiveness to risk factors in the environment. Interindividual variations in DNA repair capacity for specific types of DNA damage are documented.


Nitric Oxide Chronic Granulomatous Disease Extracellular Superoxide Dismutase Familial Combine Hyperlipidemia Atherogenic Lipoprotein Phenotype 
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© Springer 2007

Authors and Affiliations

  1. 1.Laboratory of Mutagens and ToxigenomicsNational Center for Radiation Research and TechnologyNasr CityEgypt

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