Advertisement

Preparation of Hydrophilic Antioxidant-Loaded Poly(Vinyl Alcohol) Nanoweb by Electrospinning and Its Wound Healing Effect

  • Sung Jim Lee
  • Se Geun Lee
  • Hoyoimg Kim
  • Jae Ryong Kim
  • Cha Young
  • Sun Gil Kim
  • Won Seok Lyoo
Conference paper

Abstract

Poly(vinyl alcohol) (PVA) has been used as a material for electrospinning due to its good properties in forming membranes and fibers. [1,2] Beside, it has attracted particular attention because of its inherent low toxicity, good biocompatibility, and desirable physical properties. [3] In this study, at first, electrospinning was utilized to fabricate a PVA nanoweb with antioxidant which has been used to prevent apoptosis in neuronal cells for wound dressing application. Also, PVA nanowebs with various contents of antioxidant were characterized. In the end, the wound healing effect of antioxidant-loaded PVA nanoweb was examined using male Spraque-Dawley rats with excisional wounds.

Keywords

Good Biocompatibility Vinyl Alcohol Wound Size Excisional Wound Cutaneous Wound Healing 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

References

  1. 1.
    Koski, A., Yim, K., Shivkumar, S., Mater. Lett., vol. 58, 493, 2004.CrossRefGoogle Scholar
  2. 2.
    Lee, J. S., Choi, K., Chim, H. D., Kim, S. S., Chun, D. H., Kim, H. Y., Lyoo, W. S., J. Appl. Polym. Sci., vol. 93, 1638, 2004.CrossRefGoogle Scholar
  3. 3.
    Briscoe, B., Luckham, P., Whu, S., Polymer, vol. 41, 3851, 2000.CrossRefGoogle Scholar
  4. 4.
    Zong, X. H., Kim, K., Fand, D. F., Ran, S. F., Hsiao, B. S., Chu, B., Polymer, vol. 43, 4403, 2002.CrossRefGoogle Scholar

Copyright information

© Springer 2007

Authors and Affiliations

  • Sung Jim Lee
    • 1
  • Se Geun Lee
    • 1
  • Hoyoimg Kim
    • 1
  • Jae Ryong Kim
    • 2
  • Cha Young
    • 2
  • Sun Gil Kim
    • 3
  • Won Seok Lyoo
    • 3
  1. 1.Advanced Nano Material Research TeamDaegu Gyeongbuk Institute of Science & TechnologyDaeguKorea
  2. 2.Biochemistry & Molecular Biology, College of MedicineYeungnam UniversityGyeongsanKorea
  3. 3.Division of Advanced Organic Materials, School of TextilesYeungnam UniversityGyeongsanKorea

Personalised recommendations