Preparation of Hydrophilic Antioxidant-Loaded Poly(Vinyl Alcohol) Nanoweb by Electrospinning and Its Wound Healing Effect
Poly(vinyl alcohol) (PVA) has been used as a material for electrospinning due to its good properties in forming membranes and fibers. [1,2] Beside, it has attracted particular attention because of its inherent low toxicity, good biocompatibility, and desirable physical properties.  In this study, at first, electrospinning was utilized to fabricate a PVA nanoweb with antioxidant which has been used to prevent apoptosis in neuronal cells for wound dressing application. Also, PVA nanowebs with various contents of antioxidant were characterized. In the end, the wound healing effect of antioxidant-loaded PVA nanoweb was examined using male Spraque-Dawley rats with excisional wounds.
KeywordsToxicity Amide Vinyl Thiol