Systems Level Modeling of Gene Regulatory Networks
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The perhaps most important signaling network in living cells is constituted by the interactions of proteins with the genome—the gene regulatory network of the cell. From a system level point of view, the various interactions and control loops, which form a genetic network, represent the basis upon which the vast complexity and flexibility of life processes emerges. Here we review ways by which artificial intelligence approaches can help gaining a more quantitative understanding of regulatory genetic networks at the systems level.
KeywordsRegulatory Network Bayesian Network Degree Distribution Gene Regulatory Network Genetic Network
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