Large-scale Expansion of Cells for Use as Therapeutic Agents
Expansion of cell population in vitro has become an essential step for the tissue engineering processing of articular cartilage and there is an urgent need to develop optimal culture conditions for chondrocytes. This presentation focuses on using a mathematical approach coupled with small-scale experiments to determine the optimal process parameters for cell expansion of chondroprogenitor cells and comparing the process to CHO cells expansion.
KeywordsArticular Cartilage Specific Growth Rate Cell Expansion Seeding Density Optimal Process Parameter
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