Versatile chip-based tool for the controlled manipulation of microparticles in biology using high Frequency Electromagnetic Fields

  • C. Duschl
  • P. Geggier
  • M. Jäger
  • M. Stelzle
  • T. Müller
  • T. Schnelle
  • G. R. Fuhr

Cell-based approaches in medicine, biotechnology and in the pharmaceutical research offer unique prospects to cope with future challenges in the field of public health. Stem cells, autologous cell therapies, tissue engineering and therapeutic cloning are only a few fields that are much discussed not only in the scientific community but also in the public. Progress in these fields will depend on the successful development of versatile and flexible tools for the gentle manipulation and characterisation of cells. We have developed lab-onchip microsystems based on dielectrophoresis and microfluidics that allow the contactless handling of single cells. In this chapter we overview results recently obtained in our group with an emphasis towards practical applications.

Keywords

lab-on-chip dielectrophoresis single cell manipulation microfluidics field cage stem cells cell therapy 

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Copyright information

© Springer 2004

Authors and Affiliations

  • C. Duschl
    • 1
  • P. Geggier
    • 1
  • M. Jäger
    • 1
  • M. Stelzle
    • 3
  • T. Müller
    • 2
  • T. Schnelle
    • 2
  • G. R. Fuhr
    • 1
  1. 1.Fraunhofer-Institut für Biomedizinische TechnikGermany
  2. 2.Evotec Technologies GmbHGermany
  3. 3.Naturwissenschaftliches und MedizinischesInstitut an der Universität TübingenGermany

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