Impulse conduction in the jellyfish Aglantha digitale
In the jellyfish Aglantha digitale two forms of swimming arise from two separate propagating axonal impulses: a fast, overshooting action potential that depends on TTX-resistant Na+ channels, and a lowamplitude spike that depends on T-type Ca2+ channels. While the Na+ action potential is propagated simply and without distortion, the shape of the Ca2+ spike depends on the past history of the axon; it is processed as well as propagated. Patch- and voltage-clamp experiments show how three classes of K+ channels contribute to this apparently unique system. A dual Na+/Ca2+ impulse mechanism may increase the bandwidth of an axonal line of communication but it also places restrictions on the form of the synaptic input needed for spike initiation.
Key words: T-type Ca2+ channel, TTX-insensitive Na+ channel, voltage-clamp, macropatch, K+ channel clusters, jellyfish swimming
KeywordsSynaptic Input Patch Pipette Motor Axon Nerve Ring Giant Axon
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